| # | Title | Journal | Year | Citations |
|---|
| 1 | The Galaxy platform for accessible, reproducible and collaborative biomedical analyses: 2018 update | Nucleic Acids Research | 2018 | 3,003 |
| 2 | The Galaxy platform for accessible, reproducible and collaborative biomedical analyses: 2016 update | Nucleic Acids Research | 2016 | 1,751 |
| 3 | Carbohydrate analysis by a phenol–sulfuric acid method in microplate format | Analytical Biochemistry | 2005 | 1,665 |
| 4 | Resonance Energy Transfer: Methods and Applications | Analytical Biochemistry | 1994 | 1,248 |
| 5 | The synthesis of complex carbohydrates by multiglycosyltransferase systems and their potential function in intercellular adhesion | Chemistry and Physics of Lipids | 1970 | 1,231 |
| 6 | The complete sequence of a human genome | Science | 2022 | 1,222 |
| 7 | S. cerevisiae genes required for cell cycle arrest in response to loss of microtubule function | Cell | 1991 | 1,098 |
| 8 | MetaWRAP—a flexible pipeline for genome-resolved metagenomic data analysis | Microbiome | 2018 | 1,098 |
| 9 | ER-to-Golgi transport visualized in living cells | Nature | 1997 | 1,053 |
| 10 | The proximo-distal sequence of origin of the parts of the chick wing and the role of the ectoderm | The Journal of Experimental Zoology | 1948 | 1,036 |
| 11 | Mitochondrial Fusion Is Required for mtDNA Stability in Skeletal Muscle and Tolerance of mtDNA Mutations | Cell | 2010 | 997 |
| 12 | Energetics of Protein Structure | Advances in Protein Chemistry | 1995 | 933 |
| 13 | HIV-1 evades antibody-mediated neutralization through conformational masking of receptor-binding sites | Nature | 2002 | 832 |
| 14 | ADP-ribose gating of the calcium-permeable LTRPC2 channel revealed by Nudix motif homology | Nature | 2001 | 815 |
| 15 | Mitochondrial Fusion Protects against Neurodegeneration in the Cerebellum | Cell | 2007 | 796 |
| 16 | The rapid intermixing of cell surface antigens after formation of mouse human heterokaryons | Journal of Cell Science | 1970 | 786 |
| 17 | PEYER'S PATCHES: AN ENRICHED SOURCE OF PRECURSORS FOR IGA-PRODUCING IMMUNOCYTES IN THE RABBIT | Journal of Experimental Medicine | 1971 | 768 |
| 18 | Time-Resolved Fluorescence of Proteins | Annual Review of Biochemistry | 1985 | 756 |
| 19 | Structural Basis of Mitochondrial Tethering by Mitofusin Complexes | Science | 2004 | 756 |
| 20 | Melanopsin cells are the principal conduits for rod–cone input to non-image-forming vision | Nature | 2008 | 734 |
| 21 | The Gompertz Curve as a Growth Curve | Proceedings of the National Academy of Sciences of the United States of America | 1932 | 725 |
| 22 | The dynamin-related GTPase Dnm1 regulates mitochondrial fission in yeast | Nature Cell Biology | 1999 | 708 |
| 23 | Light as a central modulator of circadian rhythms, sleep and affect | Nature Reviews Neuroscience | 2014 | 695 |
| 24 | The nucleosomal core histone octamer at 3.1 A resolution: a tripartite protein assembly and a left-handed superhelix. | Proceedings of the National Academy of Sciences of the United States of America | 1991 | 682 |
| 25 | Lactate Dehydrogenase Isozymes: Dissociation and Recombination of Subunits | Science | 1963 | 680 |
| 26 | TDP-43 Is Intrinsically Aggregation-prone, and Amyotrophic Lateral Sclerosis-linked Mutations Accelerate Aggregation and Increase Toxicity | Journal of Biological Chemistry | 2009 | 651 |
| 27 | Ca(2+)-induced Ca2+ release in sea urchin egg homogenates: modulation by cyclic ADP-ribose | Science | 1991 | 648 |
| 28 | Dnm1p Gtpase-Mediated Mitochondrial Fission Is a Multi-Step Process Requiring the Novel Integral Membrane Component Fis1p | Journal of Cell Biology | 2000 | 643 |
| 29 | Interaction of Wnt and a Frizzled homologue triggers G-protein-linked phosphatidylinositol signalling | Nature | 1997 | 622 |
| 30 | The MutT Proteins or “Nudix” Hydrolases, a Family of Versatile, Widely Distributed, “Housecleaning” Enzymes | Journal of Biological Chemistry | 1996 | 619 |
| 31 | Protein interactions with urea and guanidinium chloride | Journal of Molecular Biology | 1992 | 610 |
| 32 | Dynactin increases the processivity of the cytoplasmic dynein motor | Nature Cell Biology | 2000 | 599 |
| 33 | Intracellular Localization of Liver Sugar Nucleotide Glycoprotein Glycosyltransferases in a Golgi-rich Fraction | Journal of Biological Chemistry | 1970 | 598 |
| 34 | Receptor-mediated pinocytosis of mannose glycoconjugates by macrophages: Characterization and evidence for receptor recycling | Cell | 1980 | 585 |
| 35 | Monosaccharide analysis of glycoconjugates by anion exchange chromatography with pulsed amperometric detection | Analytical Biochemistry | 1988 | 583 |
| 36 | DYNACTIN | Annual Review of Cell and Developmental Biology | 2004 | 583 |
| 37 | Melanopsin-Expressing Retinal Ganglion-Cell Photoreceptors: Cellular Diversity and Role in Pattern Vision | Neuron | 2010 | 544 |
| 38 | Kinesin-related gene unc-104 is required for axonal transport of synaptic vesicles in C. elegans | Cell | 1991 | 537 |
| 39 | Thermodynamics of Structural Stability and Cooperative Folding Behavior in Proteins | Advances in Protein Chemistry | 1992 | 528 |
| 40 | Phosphorylation of histone H3: a balancing act between chromosome condensation and transcriptional activation | Trends in Genetics | 2004 | 516 |
| 41 | Localization of cytoplasmic dynein to mitotic spindles and kinetochores | Nature | 1990 | 509 |
| 42 | Miscarriage matters: the epidemiological, physical, psychological, and economic costs of early pregnancy loss | Lancet, The | 2021 | 508 |
| 43 | The Bacterial Phosphoenol-Pyruvate: Glycose Phosphotransferase System | Annual Review of Biochemistry | 1990 | 498 |
| 44 | Transcripts of the six Drosophila actin genes accumulate in a stage- and tissue-specific manner | Cell | 1983 | 491 |
| 45 | Reduced Nm23/Awd protein in tumour metastasis and aberrant Drosophila development | Nature | 1989 | 488 |
| 46 | Total Synthesis of a Functional Designer Eukaryotic Chromosome | Science | 2014 | 486 |
| 47 | Diffusional Mobility of Golgi Proteins in Membranes of Living Cells | Science | 1996 | 482 |
| 48 | The Parkinson's disease protein α-synuclein disrupts cellular Rab homeostasis | Proceedings of the National Academy of Sciences of the United States of America | 2008 | 479 |
| 49 | Lactate dehydrogenase isozyme patterns of fish | The Journal of Experimental Zoology | 1965 | 474 |
| 50 | Lipids on the frontier: a century of cell-membrane bilayers | Nature Reviews Molecular Cell Biology | 2003 | 473 |
