| # | Title | Journal | Year | Citations |
|---|
| 1 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 2 | Diagnosis of multiple sclerosis: 2017 revisions of the McDonald criteria | Lancet Neurology, The | 2018 | 4,605 |
| 3 | A Hexanucleotide Repeat Expansion in C9ORF72 Is the Cause of Chromosome 9p21-Linked ALS-FTD | Neuron | 2011 | 3,833 |
| 4 | Knockout of Glutamate Transporters Reveals a Major Role for Astroglial Transport in Excitotoxicity and Clearance of Glutamate | Neuron | 1996 | 2,332 |
| 5 | Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing | Nature Genetics | 2019 | 1,962 |
| 6 | Localization of neuronal and glial glutamate transporters | Neuron | 1994 | 1,575 |
| 7 | Clinical diagnosis of progressive supranuclear palsy: The movement disorder society criteria | Movement Disorders | 2017 | 1,402 |
| 8 | β-Lactam antibiotics offer neuroprotection by increasing glutamate transporter expression | Nature | 2005 | 1,379 |
| 9 | Selective loss of glial glutamate transporter GLT‐1 in amyotrophic lateral sclerosis | Annals of Neurology | 1995 | 1,356 |
| 10 | Oligodendroglia metabolically support axons and contribute to neurodegeneration | Nature | 2012 | 1,287 |
| 11 | Decreased Glutamate Transport by the Brain and Spinal Cord in Amyotrophic Lateral Sclerosis | New England Journal of Medicine | 1992 | 1,125 |
| 12 | Restless legs syndrome/Willis–Ekbom disease diagnostic criteria: updated International Restless Legs Syndrome Study Group (IRLSSG) consensus criteria – history, rationale, description, and significance | Sleep Medicine | 2014 | 1,123 |
| 13 | Restless Legs Syndrome Prevalence and Impact | Archives of Internal Medicine | 2005 | 1,046 |
| 14 | The gene for neuronal apoptosis inhibitory protein is partially deleted in individuals with spinal muscular atrophy | Cell | 1995 | 969 |
| 15 | European Federation of Neurological Societies/Peripheral Nerve Society Guideline on management of chronic inflammatory demyelinating polyradiculoneuropathy: Report of a joint task force of the European Federation of Neurological Societies and the Peripheral Nerve Society — First Revision | European Journal of Neurology | 2010 | 851 |
| 16 | The C9orf72 repeat expansion disrupts nucleocytoplasmic transport | Nature | 2015 | 835 |
| 17 | Rituximab in patients with primary progressive multiple sclerosis: Results of a randomized double‐blind placebo‐controlled multicenter trial | Annals of Neurology | 2009 | 815 |
| 18 | RNA Toxicity from the ALS/FTD C9ORF72 Expansion Is Mitigated by Antisense Intervention | Neuron | 2013 | 785 |
| 19 | Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease | Nature Genetics | 2017 | 783 |
| 20 | C9orf72 nucleotide repeat structures initiate molecular cascades of disease | Nature | 2014 | 779 |
| 21 | Electrophysiological classification of guillain‐barré syndrome: Clinical associations and outcome | Annals of Neurology | 1998 | 778 |
| 22 | Measuring Sleep: Accuracy, Sensitivity, and Specificity of Wrist Actigraphy Compared to Polysomnography | Sleep | 2013 | 740 |
| 23 | Reduction of Hippocampal Hyperactivity Improves Cognition in Amnestic Mild Cognitive Impairment | Neuron | 2012 | 736 |
| 24 | Guillain-Barré syndrome in northern China Relationship to Campylobacter jejuni infection and anti-glycolipid antibodies | Brain | 1995 | 725 |
| 25 | NG2+ CNS Glial Progenitors Remain Committed to the Oligodendrocyte Lineage in Postnatal Life and following Neurodegeneration | Neuron | 2010 | 681 |
| 26 | Immunocytochemical quantitation of human immunodeficiency virus in the brain: Correlations with dementia | Annals of Neurology | 1995 | 661 |
| 27 | Differences between human and mouse embryonic stem cells | Developmental Biology | 2004 | 656 |
| 28 | The spectrum of neuropathy in diabetes and impaired glucose tolerance | Neurology | 2003 | 645 |
| 29 | Aberrant RNA Processing in a Neurodegenerative Disease: the Cause for Absent EAAT2, a Glutamate Transporter, in Amyotrophic Lateral Sclerosis | Neuron | 1998 | 642 |
| 30 | Chronic inhibition of glutamate uptake produces a model of slow neurotoxicity. | Proceedings of the National Academy of Sciences of the United States of America | 1993 | 607 |
| 31 | Behavioural abnormalities in male mice lacking neuronal nitric oxide synthase | Nature | 1995 | 606 |
| 32 | Impact, diagnosis and treatment of restless legs syndrome (RLS) in a primary care population: the REST (RLS epidemiology, symptoms, and treatment) primary care study | Sleep Medicine | 2004 | 588 |
| 33 | Diagnosis and management of spinal muscular atrophy: Part 1: Recommendations for diagnosis, rehabilitation, orthopedic and nutritional care | Neuromuscular Disorders | 2018 | 584 |
| 34 | Nitric Oxide Synthase in Models of Focal Ischemia | Stroke | 1997 | 578 |
| 35 | Interrater reliability in myofascial trigger point examination | Pain | 1997 | 574 |
| 36 | Reduced Striatal Dopamine Transporter Density in Abstinent Methamphetamine and Methcathinone Users: Evidence from Positron Emission Tomography Studies with [11C]WIN-35,428 | Journal of Neuroscience | 1998 | 570 |
| 37 | The Metabolic Profile of Tumors Depends on Both the Responsible Genetic Lesion and Tissue Type | Cell Metabolism | 2012 | 553 |
| 38 | Interoception and Mental Health: A Roadmap | Biological Psychiatry: Cognitive Neuroscience and Neuroimaging | 2018 | 524 |
| 39 | Genome-wide Analyses Identify KIF5A as a Novel ALS Gene | Neuron | 2018 | 517 |
| 40 | Microtubule Stabilization Reduces Scarring and Causes Axon Regeneration After Spinal Cord Injury | Science | 2011 | 503 |
| 41 | Dimethyl fumarate targets GAPDH and aerobic glycolysis to modulate immunity | Science | 2018 | 489 |
| 42 | Reconstructing Speech from Human Auditory Cortex | PLoS Biology | 2012 | 486 |
| 43 | Wallerian degeneration in the peripheral nervous system: participation of both Schwann cells and macrophages in myelin degradation | Journal of Neurocytology | 1989 | 485 |
| 44 | Inhibition of neuronal ferroptosis protects hemorrhagic brain | JCI Insight | 2017 | 483 |
| 45 | Diagnostic criteria for psychosis in Parkinson's disease: Report of an NINDS, NIMH work group | Movement Disorders | 2007 | 474 |
| 46 | Synphilin-1 associates with α-synuclein and promotes the formation of cytosolic inclusions | Nature Genetics | 1999 | 473 |
| 47 | Human sensorimotor learning: adaptation, skill, and beyond | Current Opinion in Neurobiology | 2011 | 425 |
| 48 | Diagnosis and management of spinal muscular atrophy: Part 2: Pulmonary and acute care; medications, supplements and immunizations; other organ systems; and ethics | Neuromuscular Disorders | 2018 | 421 |
| 49 | Associations Between Midlife Vascular Risk Factors and 25-Year Incident Dementia in the Atherosclerosis Risk in Communities (ARIC) Cohort | JAMA Neurology | 2017 | 404 |
| 50 | Neural subsystems for object knowledge | Nature | 1992 | 403 |
