| # | Title | Journal | Year | Citations |
|---|
| 1 | The Immune Landscape of Cancer | Immunity | 2018 | 3,706 |
| 2 | Genetic effects on gene expression across human tissues | Nature | 2017 | 3,500 |
| 3 | Improved metagenomic analysis with Kraken 2 | Genome Biology | 2019 | 2,909 |
| 4 | Phased diploid genome assembly with single-molecule real-time sequencing | Nature Methods | 2016 | 1,658 |
| 5 | The complete sequence of a human genome | Science | 2022 | 1,222 |
| 6 | Some Computer Organizations and Their Effectiveness | IEEE Transactions on Computers | 1972 | 1,076 |
| 7 | Accurate circular consensus long-read sequencing improves variant detection and assembly of a human genome | Nature Biotechnology | 2019 | 1,010 |
| 8 | Advances in computational stereo | IEEE Transactions on Pattern Analysis and Machine Intelligence | 2003 | 900 |
| 9 | Transcriptome assembly from long-read RNA-seq alignments with StringTie2 | Genome Biology | 2019 | 897 |
| 10 | Saturated Reconstruction of a Volume of Neocortex | Cell | 2015 | 870 |
| 11 | The grand challenges of Science Robotics | Science Robotics | 2018 | 787 |
| 12 | A Complete Electron Microscopy Volume of the Brain of Adult Drosophila melanogaster | Cell | 2018 | 731 |
| 13 | Fast and globally convergent pose estimation from video images | IEEE Transactions on Pattern Analysis and Machine Intelligence | 2000 | 686 |
| 14 | On Comparing Classifiers: Pitfalls to Avoid and a Recommended Approach | Data Mining and Knowledge Discovery | 1997 | 653 |
| 15 | Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression | Nature Genetics | 2021 | 590 |
| 16 | Zerocoin: Anonymous Distributed E-Cash from Bitcoin | | 2013 | 565 |
| 17 | Wireless Sensor Networks for Healthcare | Proceedings of the IEEE | 2010 | 516 |
| 18 | Genetic CNN | | 2017 | 504 |
| 19 | Transient structural variations have strong effects on quantitative traits and reproductive isolation in fission yeast | Nature Communications | 2017 | 472 |
| 20 | RaGOO: fast and accurate reference-guided scaffolding of draft genomes | Genome Biology | 2019 | 469 |
| 21 | Scaling read aligners to hundreds of threads on general-purpose processors | Bioinformatics | 2019 | 467 |
| 22 | Major Impacts of Widespread Structural Variation on Gene Expression and Crop Improvement in Tomato | Cell | 2020 | 464 |
| 23 | Comparing Physician and Artificial Intelligence Chatbot Responses to Patient Questions Posted to a Public Social Media Forum | JAMA Internal Medicine | 2023 | 455 |
| 24 | Charm: a framework for rapidly prototyping cryptosystems | Journal of Cryptographic Engineering | 2013 | 451 |
| 25 | Adversarial Examples for Semantic Segmentation and Object Detection | | 2017 | 435 |
| 26 | A weighted nearest neighbor algorithm for learning with symbolic features | Machine Learning | 1993 | 415 |
| 27 | Reproducible RNA-seq analysis using recount2 | Nature Biotechnology | 2017 | 395 |
| 28 | Piercing the dark matter: bioinformatics of long-range sequencing and mapping | Nature Reviews Genetics | 2018 | 395 |
| 29 | A targeted real-time early warning score (TREWScore) for septic shock | Science Translational Medicine | 2015 | 389 |
| 30 | Rcorrector: efficient and accurate error correction for Illumina RNA-seq reads | GigaScience | 2015 | 381 |
| 31 | Supervised autonomous robotic soft tissue surgery | Science Translational Medicine | 2016 | 374 |
| 32 | A public turbulence database cluster and applications to study Lagrangian evolution of velocity increments in turbulence | Journal of Turbulence | 2008 | 373 |
| 33 | Medical robotics—Regulatory, ethical, and legal considerations for increasing levels of autonomy | Science Robotics | 2017 | 349 |
| 34 | Design and Integration of a Telerobotic System for Minimally Invasive Surgery of the Throat | International Journal of Robotics Research | 2009 | 342 |
| 35 | A Weighted Nearest Neighbor Algorithm for Learning with Symbolic Features | Machine Learning | 1993 | 339 |
| 36 | Combining Search, Social Media, and Traditional Data Sources to Improve Influenza Surveillance | PLoS Computational Biology | 2015 | 338 |
| 37 | The impact of structural variation on human gene expression | Nature Genetics | 2017 | 334 |
| 38 | The impact of sex on gene expression across human tissues | Science | 2020 | 329 |
| 39 | Almost optimal set covers in finite VC-dimension | Discrete and Computational Geometry | 1995 | 314 |
| 40 | MR-PDP: Multiple-Replica Provable Data Possession | | 2008 | 312 |
| 41 | An open-source research kit for the da Vinci® Surgical System | | 2014 | 309 |
| 42 | Using Smartphones and Machine Learning to Quantify Parkinson Disease Severity | JAMA Neurology | 2018 | 303 |
| 43 | Assemblytics: a web analytics tool for the detection of variants from an assembly | Bioinformatics | 2016 | 295 |
| 44 | Surgical data science for next-generation interventions | Nature Biomedical Engineering | 2017 | 283 |
| 45 | Whole-brain serial-section electron microscopy in larval zebrafish | Nature | 2017 | 282 |
| 46 | CHESS: a new human gene catalog curated from thousands of large-scale RNA sequencing experiments reveals extensive transcriptional noise | Genome Biology | 2018 | 263 |
| 47 | Minimum information about clinical artificial intelligence modeling: the MI-CLAIM checklist | Nature Medicine | 2020 | 262 |
| 48 | Adaptive and Generic Corner Detection Based on the Accelerated Segment Test | Lecture Notes in Computer Science | 2010 | 256 |
| 49 | Patient geometry‐driven information retrieval for IMRT treatment plan quality control | Medical Physics | 2009 | 250 |
| 50 | Public Key Encryption with Conjunctive Keyword Search and Its Extension to a Multi-user System | Lecture Notes in Computer Science | 2007 | 232 |
