| # | Title | Journal | Year | Citations |
|---|
| 1 | Acute-on-Chronic Liver Failure Is a Distinct Syndrome That Develops in Patients With Acute Decompensation of Cirrhosis | Gastroenterology | 2013 | 2,211 |
| 2 | 2019 update of the EULAR recommendations for the management of systemic lupus erythematosus | Annals of the Rheumatic Diseases | 2019 | 1,265 |
| 3 | Patient-derived organoids model treatment response of metastatic gastrointestinal cancers | Science | 2018 | 1,199 |
| 4 | Peripheral cytokine and chemokine alterations in depression: a meta‐analysis of 82 studies | Acta Psychiatrica Scandinavica | 2017 | 946 |
| 5 | Joint European League Against Rheumatism and European Renal Association–European Dialysis and Transplant Association (EULAR/ERA-EDTA) recommendations for the management of adult and paediatric lupus nephritis | Annals of the Rheumatic Diseases | 2012 | 868 |
| 6 | Risk thresholds for alcohol consumption: combined analysis of individual-participant data for 599 912 current drinkers in 83 prospective studies | Lancet, The | 2018 | 858 |
| 7 | Whole-genome landscape of pancreatic neuroendocrine tumours | Nature | 2017 | 716 |
| 8 | Visceral and ectopic fat, atherosclerosis, and cardiometabolic disease: a position statement | Lancet Diabetes and Endocrinology,the | 2019 | 687 |
| 9 | Bacterial infections in cirrhosis: A position statement based on the EASL Special Conference 2013 | Journal of Hepatology | 2014 | 685 |
| 10 | EULAR recommendations for women's health and the management of family planning, assisted reproduction, pregnancy and menopause in patients with systemic lupus erythematosus and/or antiphospholipid syndrome | Annals of the Rheumatic Diseases | 2017 | 590 |
| 11 | Rivaroxaban vs warfarin in high-risk patients with antiphospholipid syndrome | Blood | 2018 | 573 |
| 12 | Integrated genomic characterization of adrenocortical carcinoma | Nature Genetics | 2014 | 560 |
| 13 | Systemic inflammation in decompensated cirrhosis: Characterization and role in acute‐on‐chronic liver failure | Hepatology | 2016 | 550 |
| 14 | Long-term study of patients with type 2 diabetes and moderate renal impairment shows that dapagliflozin reduces weight and blood pressure but does not improve glycemic control | Kidney International | 2014 | 532 |
| 15 | Acute kidney injury | Nature Reviews Disease Primers | 2021 | 509 |
| 16 | Somatic mutations in ATP1A1 and ATP2B3 lead to aldosterone-producing adenomas and secondary hypertension | Nature Genetics | 2013 | 460 |
| 17 | Inflammation and sarcopenia: A systematic review and meta-analysis | Maturitas | 2017 | 451 |
| 18 | Androgen-deprivation therapies for prostate cancer and risk of infection by SARS-CoV-2: a population-based study (N = 4532) | Annals of Oncology | 2020 | 447 |
| 19 | Mapping and predicting mortality from systemic sclerosis | Annals of the Rheumatic Diseases | 2017 | 410 |
| 20 | Mismatch Repair Deficiency, Microsatellite Instability, and Survival | JAMA Oncology | 2017 | 398 |
| 21 | Recurrence after resection for ductal adenocarcinoma of the pancreas | World Journal of Surgery | 1997 | 381 |
| 22 | Prevalence and impact of diabetes among people infected with SARS-CoV-2 | Journal of Endocrinological Investigation | 2020 | 371 |
| 23 | 2021 European Society of Hypertension practice guidelines for office and out-of-office blood pressure measurement | Journal of Hypertension | 2021 | 349 |
| 24 | Long-term albumin administration in decompensated cirrhosis (ANSWER): an open-label randomised trial | Lancet, The | 2018 | 345 |
| 25 | Recommendations on Acute Kidney Injury Biomarkers From the Acute Disease Quality Initiative Consensus Conference | JAMA Network Open | 2020 | 335 |
| 26 | Diagnosis, Evaluation, and Management of Ascites, Spontaneous Bacterial Peritonitis and Hepatorenal Syndrome: 2021 Practice Guidance by the American Association for the Study of Liver Diseases | Hepatology | 2021 | 311 |
| 27 | Epidemiology and Effects of Bacterial Infections in Patients With Cirrhosis Worldwide | Gastroenterology | 2019 | 296 |
| 28 | How much physical activity do people with schizophrenia engage in? A systematic review, comparative meta-analysis and meta-regression | Schizophrenia Research | 2016 | 284 |
| 29 | Hypoalbuminemia | Internal and Emergency Medicine | 2012 | 283 |
| 30 | The PREDICT study uncovers three clinical courses of acutely decompensated cirrhosis that have distinct pathophysiology | Journal of Hepatology | 2020 | 282 |
| 31 | SGLT2 Inhibitors and the Diabetic Kidney | Diabetes Care | 2016 | 279 |
| 32 | Coronavirus disease 2019 in patients with inborn errors of immunity: An international study | Journal of Allergy and Clinical Immunology | 2021 | 278 |
| 33 | CCL2/CCR2, but not CCL5/CCR5, mediates monocyte recruitment, inflammation and cartilage destruction in osteoarthritis | Annals of the Rheumatic Diseases | 2017 | 277 |
| 34 | Three Decades of Comprehensive Geriatric Assessment: Evidence Coming From Different Healthcare Settings and Specific Clinical Conditions | Journal of the American Medical Directors Association | 2017 | 277 |
| 35 | News in pathophysiology, definition and classification of hepatorenal syndrome: A step beyond the International Club of Ascites (ICA) consensus document | Journal of Hepatology | 2019 | 272 |
| 36 | A framework for remission in SLE: consensus findings from a large international task force on definitions of remission in SLE (DORIS) | Annals of the Rheumatic Diseases | 2017 | 268 |
| 37 | Impact of Diabetes on Epidemiology, Treatment, and Outcomes of Patients With Heart Failure | JACC: Heart Failure | 2015 | 265 |
| 38 | Association of Office and Ambulatory Blood Pressure With Mortality and Cardiovascular Outcomes | JAMA - Journal of the American Medical Association | 2019 | 265 |
| 39 | European Practical and Patient-Centred Guidelines for Adult Obesity Management in Primary Care | Obesity Facts | 2019 | 260 |
| 40 | Characteristics, risk factors, and mortality of cirrhotic patients hospitalized for hepatic encephalopathy with and without acute-on-chronic liver failure (ACLF) | Journal of Hepatology | 2014 | 259 |
| 41 | Management of the critically ill patient with cirrhosis: A multidisciplinary perspective | Journal of Hepatology | 2016 | 243 |
| 42 | NETosis Delays Diabetic Wound Healing in Mice and Humans | Diabetes | 2016 | 233 |
| 43 | Evaluation of the Acute Kidney Injury Network criteria in hospitalized patients with cirrhosis and ascites | Journal of Hepatology | 2013 | 232 |
| 44 | Cobalamin Deficiency: Clinical Picture and Radiological Findings | Nutrients | 2013 | 232 |
| 45 | Gitelman syndrome: consensus and guidance from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference | Kidney International | 2017 | 230 |
| 46 | 2018 updated European League Against Rheumatism evidence-based recommendations for the diagnosis of gout | Annals of the Rheumatic Diseases | 2020 | 225 |
| 47 | Blood metabolomics uncovers inflammation-associated mitochondrial dysfunction as a potential mechanism underlying ACLF | Journal of Hepatology | 2020 | 223 |
| 48 | Hepatic encephalopathy: Novel insights into classification, pathophysiology and therapy | Journal of Hepatology | 2020 | 219 |
| 49 | Klinefelter syndrome (KS): genetics, clinical phenotype and hypogonadism | Journal of Endocrinological Investigation | 2017 | 210 |
| 50 | Survival after resection for ductal adenocarcinoma of the pancreas | British Journal of Surgery | 2005 | 207 |
