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Center for Genome Engineering
›
top-articles
Center for Genome Engineering
108
(top 1%)
papers
10.0K
(top 1%)
citations
45
(top 1%)
h
-index
100
(top 1%)
g
-index
123
all documents
11.3K
doc citations
1.7K
citing journals
Top Articles
#
Title
Journal
Year
Citations
1
Microbial Hub Taxa Link Host and Abiotic Factors to Plant Microbiome Variation
PLoS Biology
2016
1,065
2
A guide to genome engineering with programmable nucleases
Nature Reviews Genetics
2014
990
3
DNA-free genome editing in plants with preassembled CRISPR-Cas9 ribonucleoproteins
Nature Biotechnology
2015
975
4
Digenome-seq: genome-wide profiling of CRISPR-Cas9 off-target effects in human cells
Nature Methods
2015
850
5
Correction of a pathogenic gene mutation in human embryos
Nature
2017
781
6
CRISPR/Cpf1-mediated DNA-free plant genome editing
Nature Communications
2017
386
7
Adenine base editing in mouse embryos and an adult mouse model of Duchenne muscular dystrophy
Nature Biotechnology
2018
345
8
Microhomology-based choice of Cas9 nuclease target sites
Nature Methods
2014
336
9
Highly efficient RNA-guided base editing in mouse embryos
Nature Biotechnology
2017
330
10
Cas-analyzer: an online tool for assessing genome editing results using NGS data
Bioinformatics
2017
313
11
DNA-free two-gene knockout in Chlamydomonas reinhardtii via CRISPR-Cas9 ribonucleoproteins
Scientific Reports
2016
253
12
Precision genome engineering through adenine base editing in plants
Nature Plants
2018
227
13
Targeted mutagenesis in mice by electroporation of Cpf1 ribonucleoproteins
Nature Biotechnology
2016
191
14
Genome-wide target specificities of CRISPR-Cas9 nucleases revealed by multiplex Digenome-seq
Genome Research
2016
184
15
Measuring and Reducing Off-Target Activities of Programmable Nucleases Including CRISPR-Cas9
Molecules and Cells
2015
181
16
CRISPR RNAs trigger innate immune responses in human cells
Genome Research
2018
177
17
Genome-wide target specificity of CRISPR RNA-guided adenine base editors
Nature Biotechnology
2019
151
18
Direct observation of DNA target searching and cleavage by CRISPR-Cas12a
Nature Communications
2018
148
19
Stem-piped light activates phytochrome B to trigger light responses in
Arabidopsis thaliana
roots
Science Signaling
2016
145
20
Genome surgery using Cas9 ribonucleoproteins for the treatment of age-related macular degeneration
Genome Research
2017
136
21
Web-based design and analysis tools for CRISPR base editing
BMC Bioinformatics
2018
127
22
Evaluating and Enhancing Target Specificity of Gene-Editing Nucleases and Deaminases
Annual Review of Biochemistry
2019
120
23
The road ahead in genetics and genomics
Nature Reviews Genetics
2020
118
24
Efficient delivery of nuclease proteins for genome editing in human stem cells and primary cells
Nature Protocols
2015
113
25
Systemic Immunity Requires SnRK2.8-Mediated Nuclear Import of NPR1 in Arabidopsis
Plant Cell
2015
104
26
Targeted A-to-G base editing in human mitochondrial DNA with programmable deaminases
Cell
2022
102
27
Adenine base editors catalyze cytosine conversions in human cells
Nature Biotechnology
2019
95
28
Structural roles of guide RNAs in the nuclease activity of Cas9 endonuclease
Nature Communications
2016
94
29
Chloroplast and mitochondrial DNA editing in plants
Nature Plants
2021
91
30
CRISPR
/Cas9‐mediated editing of 1‐aminocyclopropane‐1‐carboxylate oxidase1 enhances
Petunia
flower longevity
Plant Biotechnology Journal
2020
90
31
Mitochondrial DNA editing in mice with DddA-TALE fusion deaminases
Nature Communications
2021
86
32
Genome editing comes of age
Nature Protocols
2016
85
33
CUT-PCR: CRISPR-mediated, ultrasensitive detection of target DNA using PCR
Oncogene
2017
84
34
Transcriptional regulatory framework for vascular cambium development in Arabidopsis roots
Nature Plants
2019
81
35
CRISPR
/Cas9 searches for a protospacer adjacent motif by lateral diffusion
EMBO Journal
2019
80
36
Rescue of high-specificity Cas9 variants using sgRNAs with matched 5’ nucleotides
Genome Biology
2017
73
37
Silencing
Nicotiana attenuata
LHY
and
ZTL
alters circadian rhythms in flowers
New Phytologist
2016
71
38
CRISPR-LbCpf1 prevents choroidal neovascularization in a mouse model of age-related macular degeneration
Nature Communications
2018
71
39
Precision genome engineering through adenine and cytosine base editing
Nature Plants
2018
69
40
Targeted mutagenesis in mouse cells and embryos using an enhanced prime editor
Genome Biology
2021
66
41
A simple, flexible and high‐throughput cloning system for plant genome editing via CRISPR‐Cas system
Journal of Integrative Plant Biology
2016
61
42
PE-Designer and PE-Analyzer: web-based design and analysis tools for CRISPR prime editing
Nucleic Acids Research
2021
57
43
N-terminal arginylation generates a bimodal degron that modulates autophagic proteolysis
Proceedings of the National Academy of Sciences of the United States of America
2018
56
44
Generation of cloned adult muscular pigs with myostatin gene mutation by genetic engineering
RSC Advances
2017
55
45
Phase 1 clinical trial of CRISPR-engineered CAR19 universal T cells for treatment of children with refractory B cell leukemia
Science Translational Medicine
2022
52
46
dCas9-mediated Nanoelectrokinetic Direct Detection of Target Gene for Liquid Biopsy
Nano Letters
2018
50
47
Adenine base editor engineering reduces editing of bystander cytosines
Nature Biotechnology
2021
50
48
Arrayed CRISPR screen with image-based assay reliably uncovers host genes required for coxsackievirus infection
Genome Research
2018
45
49
Nuclear and mitochondrial DNA editing in human cells with zinc finger deaminases
Nature Communications
2022
43
50
Synaptotagmin 1 Negatively Controls the Two Distinct Immune Secretory Pathways to Powdery Mildew Fungi in Arabidopsis
Plant and Cell Physiology
2016
39
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