| # | Title | Journal | Year | Citations |
|---|
| 1 | Risk-adapted targeted intraoperative radiotherapy versus whole-breast radiotherapy for breast cancer: 5-year results for local control and overall survival from the TARGIT-A randomised trial | Lancet, The | 2014 | 740 |
| 2 | Targeted intraoperative radiotherapy versus whole breast radiotherapy for breast cancer (TARGIT-A trial): an international, prospective, randomised, non-inferiority phase 3 trial | Lancet, The | 2010 | 677 |
| 3 | Magnetic Resonance Imaging for the Detection, Localisation, and Characterisation of Prostate Cancer: Recommendations from a European Consensus Meeting | European Urology | 2011 | 642 |
| 4 | Neoantigen-directed immune escape in lung cancer evolution | Nature | 2019 | 639 |
| 5 | International consensus statement on the peri‐operative management of anaemia and iron deficiency | Anaesthesia | 2017 | 571 |
| 6 | Osteoinduction of bone grafting materials for bone repair and regeneration | Bone | 2015 | 469 |
| 7 | Automatic Multi-Organ Segmentation on Abdominal CT With Dense V-Networks | IEEE Transactions on Medical Imaging | 2018 | 436 |
| 8 | Overexpression of LSD1 contributes to human carcinogenesis through chromatin regulation in various cancers | International Journal of Cancer | 2011 | 420 |
| 9 | Focal therapy for localised unifocal and multifocal prostate cancer: a prospective development study | Lancet Oncology, The | 2012 | 359 |
| 10 | Complications After Systematic, Random, and Image-guided Prostate Biopsy | European Urology | 2017 | 353 |
| 11 | Injectable Stem Cell‐Laden Photocrosslinkable Microspheres Fabricated Using Microfluidics for Rapid Generation of Osteogenic Tissue Constructs | Advanced Functional Materials | 2016 | 309 |
| 12 | Detection of Mycoplasma in cell cultures | Nature Protocols | 2010 | 303 |
| 13 | Liver ischemia/reperfusion injury: Processes in inflammatory networks-A review | Liver Transplantation | 2010 | 296 |
| 14 | Early detection of cancer | Science | 2022 | 291 |
| 15 | Weakly-supervised convolutional neural networks for multimodal image registration | Medical Image Analysis | 2018 | 280 |
| 16 | Multiresponsive Graphene‐Aerogel‐Directed Phase‐Change Smart Fibers | Advanced Materials | 2018 | 272 |
| 17 | Padeliporfin vascular-targeted photodynamic therapy versus active surveillance in men with low-risk prostate cancer (CLIN1001 PCM301): an open-label, phase 3, randomised controlled trial | Lancet Oncology, The | 2017 | 263 |
| 18 | Characterizing Clinically Significant Prostate Cancer Using Template Prostate Mapping Biopsy | Journal of Urology | 2011 | 253 |
| 19 | Skin regeneration scaffolds: a multimodal bottom-up approach | Trends in Biotechnology | 2012 | 242 |
| 20 | Sonodynamic Therapy: Concept, Mechanism and Application to Cancer Treatment | Advances in Experimental Medicine and Biology | 2016 | 237 |
| 21 | Enhanced Recovery after Urological Surgery: A Contemporary Systematic Review of Outcomes, Key Elements, and Research Needs | European Urology | 2016 | 230 |
| 22 | pH and Glucose Dual-Responsive Injectable Hydrogels with Insulin and Fibroblasts as Bioactive Dressings for Diabetic Wound Healing | ACS Applied Materials & Interfaces | 2017 | 227 |
| 23 | Focal Therapy for Localized Prostate Cancer: A Phase I/II Trial | Journal of Urology | 2011 | 223 |
| 24 | Multiparametric MRI for prostate cancer diagnosis: current status and future directions | Nature Reviews Urology | 2020 | 207 |
| 25 | Focal Therapy: Patients, Interventions, and Outcomes—A Report from a Consensus Meeting | European Urology | 2015 | 206 |
| 26 | Pan-cancer deconvolution of tumour composition using DNA methylation | Nature Communications | 2018 | 205 |
| 27 | Cancer prevention in Europe | European Journal of Cancer Prevention | 2013 | 196 |
| 28 | Management of prostate cancer in older patients: updated recommendations of a working group of the International Society of Geriatric Oncology | Lancet Oncology, The | 2014 | 196 |
| 29 | Nanomaterials in combating cancer: Therapeutic applications and developments | Nanomedicine: Nanotechnology, Biology, and Medicine | 2014 | 192 |
| 30 | 2020 World Society of Emergency Surgery updated guidelines for the diagnosis and treatment of acute calculus cholecystitis | World Journal of Emergency Surgery | 2020 | 186 |
| 31 | Topical haemostatic agents | British Journal of Surgery | 2008 | 184 |
| 32 | ‘Fit to fly’: overcoming barriers to preoperative haemoglobin optimization in surgical patients | British Journal of Anaesthesia | 2015 | 181 |
| 33 | Microvascular disease and risk of cardiovascular events among individuals with type 2 diabetes: a population-level cohort study | Lancet Diabetes and Endocrinology,the | 2016 | 175 |
| 34 | Aspartic Acid Racemization and Collagen Degradation Markers Reveal an Accumulation of Damage in Tendon Collagen That Is Enhanced with Aging | Journal of Biological Chemistry | 2010 | 172 |
| 35 | Overweight, obesity, and risk of hospitalization for COVID-19: A community-based cohort study of adults in the United Kingdom | Proceedings of the National Academy of Sciences of the United States of America | 2020 | 171 |
| 36 | Long term survival and local control outcomes from single dose targeted intraoperative radiotherapy during lumpectomy (TARGIT-IORT) for early breast cancer: TARGIT-A randomised clinical trial | BMJ, The | 2020 | 165 |
| 37 | Focal Ablation Targeted to the Index Lesion in Multifocal Localised Prostate Cancer: a Prospective Development Study | European Urology | 2015 | 163 |
| 38 | Physical and mental health 3 months after SARS-CoV-2 infection (long COVID) among adolescents in England (CLoCk): a national matched cohort study | The Lancet Child and Adolescent Health | 2022 | 160 |
| 39 | Nitric Oxide: A Guardian for Vascular Grafts? | Chemical Reviews | 2011 | 157 |
| 40 | Molecular mechanisms of liver ischemia reperfusion injury: Insights from transgenic knockout models | World Journal of Gastroenterology | 2013 | 155 |
| 41 | Fluorescence nanoparticles “quantum dots” as drug delivery system and their toxicity: a review | Journal of Drug Targeting | 2011 | 153 |
| 42 | Effects of Regular Physical Activity on the Immune System, Vaccination and Risk of Community-Acquired Infectious Disease in the General Population: Systematic Review and Meta-Analysis | Sports Medicine | 2021 | 152 |
| 43 | Do low-grade and low-volume prostate cancers bear the hallmarks of malignancy? | Lancet Oncology, The | 2012 | 150 |
| 44 | Low energy availability surrogates correlate with health and performance consequences of Relative Energy Deficiency in Sport | British Journal of Sports Medicine | 2019 | 127 |
| 45 | Photodynamic therapy: Inception to application in breast cancer | Breast | 2017 | 126 |
| 46 | Long-Term Results of Targeted Intraoperative Radiotherapy (Targit) Boost During Breast-Conserving Surgery | International Journal of Radiation Oncology Biology Physics | 2011 | 125 |
| 47 | Scoring systems used for the interpretation and reporting of multiparametric MRI for prostate cancer detection, localization, and characterization: could standardization lead to improved utilization of imaging within the diagnostic pathway? | Journal of Magnetic Resonance Imaging | 2013 | 119 |
| 48 | The role of iron in the skin and cutaneous wound healing | Frontiers in Pharmacology | 2014 | 117 |
| 49 | Improved in vivo delivery of m-THPC via pegylated liposomes for use in photodynamic therapy | Journal of Controlled Release | 2012 | 116 |
| 50 | Initial assessment of safety and clinical feasibility of irreversible electroporation in the focal treatment of prostate cancer | Prostate Cancer and Prostatic Diseases | 2014 | 116 |
