# | Title | Journal | Year | Citations |
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1 | Haemodynamic definitions and updated clinical classification of pulmonary hypertension | European Respiratory Journal | 2019 | 2,583 |
2 | Joint European League Against Rheumatism and European Renal Association–European Dialysis and Transplant Association (EULAR/ERA-EDTA) recommendations for the management of adult and paediatric lupus nephritis | Annals of the Rheumatic Diseases | 2012 | 868 |
3 | CD19 + CD24 hi CD38 hi B Cells Maintain Regulatory T Cells While Limiting T H 1 and T H 17 Differentiation | Science Translational Medicine | 2013 | 564 |
4 | The importance of natural IgM: scavenger, protector and regulator | Nature Reviews Immunology | 2010 | 491 |
5 | Serologic changes following B lymphocyte depletion therapy for rheumatoid arthritis | Arthritis and Rheumatism | 2003 | 424 |
6 | Regulatory B cells are induced by gut microbiota–driven interleukin-1β and interleukin-6 production | Nature Medicine | 2014 | 373 |
7 | The frequency and outcome of lupus nephritis: results from an international inception cohort study | Rheumatology | 2016 | 370 |
8 | B-cell depletion in the treatment of patients with systemic lupus erythematosus: a longitudinal analysis of 24 patients | Rheumatology | 2005 | 339 |
9 | Regulation and function of connective tissue growth factor/CCN2 in tissue repair, scarring and fibrosis | Cytokine and Growth Factor Reviews | 2008 | 339 |
10 | A Regulatory Feedback between Plasmacytoid Dendritic Cells and Regulatory B Cells Is Aberrant in Systemic Lupus Erythematosus | Immunity | 2016 | 303 |
11 | Human FoxP3+ regulatory T cells in systemic autoimmune diseases | Autoimmunity Reviews | 2011 | 298 |
12 | Clinical outcome in 22 patients with rheumatoid arthritis treated with B lymphocyte depletion | Annals of the Rheumatic Diseases | 2002 | 294 |
13 | Influence of race/ethnicity on response to lupus nephritis treatment: the ALMS study | Rheumatology | 2010 | 290 |
14 | The British Society for Rheumatology guideline for the management of systemic lupus erythematosus in adults | Rheumatology | 2018 | 247 |
15 | Defects in CTLA-4 are associated with abnormal regulatory T cell function in rheumatoid arthritis | Proceedings of the National Academy of Sciences of the United States of America | 2008 | 244 |
16 | Interleukin-10 produced by B cells is crucial for the suppression of Th17/Th1 responses, induction of T regulatory type 1 cells and reduction of collagen-induced arthritis | Arthritis Research and Therapy | 2012 | 236 |
17 | The expanding family of regulatory B cells | International Immunology | 2015 | 236 |
18 | Germinal center B cells govern their own fate via antibody feedback | Journal of Experimental Medicine | 2013 | 231 |
19 | Efficacy and safety of atacicept for prevention of flares in patients with moderate-to-severe systemic lupus erythematosus (SLE): 52-week data (APRIL-SLE randomised trial) | Annals of the Rheumatic Diseases | 2015 | 231 |
20 | 14th International Congress on Antiphospholipid Antibodies Task Force. Report on antiphospholipid syndrome laboratory diagnostics and trends | Autoimmunity Reviews | 2014 | 224 |
21 | Increased circulating platelet-leucocyte complexes and platelet activation in patients with antiphospholipid syndrome, systemic lupus erythematosus and rheumatoid arthritis | British Journal of Haematology | 2001 | 217 |
22 | Adoptive therapy with redirected primary regulatory T cells results in antigen-specific suppression of arthritis | Proceedings of the National Academy of Sciences of the United States of America | 2009 | 183 |
23 | Iloprost suppresses connective tissue growth factor production in fibroblasts and in the skin of scleroderma patients | Journal of Clinical Investigation | 2001 | 178 |
24 | Steroid injection for heel pain: evidence of short-term effectiveness. A randomized controlled trial | Rheumatology | 1999 | 169 |
25 | Do self‐perpetuating B lymphocytes drive human autoimmune disease? | Immunology | 1999 | 163 |
26 | Autoimmune thyroid disease in systemic lupus erythematosus | Annals of the Rheumatic Diseases | 2002 | 157 |
27 | Anti-TNF drives regulatory T cell expansion by paradoxically promoting membrane TNF–TNF-RII binding in rheumatoid arthritis | Journal of Experimental Medicine | 2016 | 152 |
28 | European Dermatology Forum S1‐guideline on the diagnosis and treatment of sclerosing diseases of the skin, Part 1: localized scleroderma, systemic sclerosis and overlap syndromes | Journal of the European Academy of Dermatology and Venereology | 2017 | 148 |
29 | B cell depletion therapy in systemic lupus erythematosus: long-term follow-up and predictors of response | Annals of the Rheumatic Diseases | 2007 | 145 |
30 | Expression of integrin β1 by fibroblasts is required for tissue repair in vivo | Journal of Cell Science | 2010 | 142 |
31 | Repeated B lymphocyte depletion with rituximab in rheumatoid arthritis over 7 yrs | Rheumatology | 2006 | 141 |
32 | PREVALENCE OF SELF-REPORTED DEPRESSION IN PATIENTS WITH RHEUMATOID ARTHRITIS | Rheumatology | 1996 | 137 |
33 | Influence of geolocation and ethnicity on the phenotypic expression of primary Sjögren's syndrome at diagnosis in 8310 patients: a cross-sectional study from the Big Data Sjögren Project Consortium | Annals of the Rheumatic Diseases | 2017 | 132 |
34 | Elevated Serum BAFF Levels Are Associated With Rising Anti–Double‐Stranded DNA Antibody Levels and Disease Flare Following B Cell Depletion Therapy in Systemic Lupus Erythematosus | Arthritis and Rheumatism | 2013 | 128 |
35 | Matrix Contraction by Dermal Fibroblasts Requires Transforming Growth Factor-β/Activin-Linked Kinase 5, Heparan Sulfate-Containing Proteoglycans, and MEK/ERK | American Journal of Pathology | 2005 | 127 |
36 | Fibroblast-specific Expression of a Kinase-deficient Type II Transforming Growth Factor β (TGFβ) Receptor Leads to Paradoxical Activation of TGFβ Signaling Pathways with Fibrosis in Transgenic Mice | Journal of Biological Chemistry | 2003 | 126 |
37 | Incidence of cancer in a cohort of patients with primary Sjögren's syndrome | Rheumatology | 2006 | 122 |
38 | A clinical update on the significance of the gut microbiota in systemic autoimmunity | Journal of Autoimmunity | 2016 | 122 |
39 | Lupus disease activity and the risk of subsequent organ damage and mortality in a large lupus cohort | Rheumatology | 2012 | 120 |
40 | The juvenile idiopathic inflammatory myopathies: pathogenesis, clinical and autoantibody phenotypes, and outcomes | Journal of Internal Medicine | 2016 | 117 |
41 | Lipid rafts in T cell signalling and disease | Seminars in Cell and Developmental Biology | 2007 | 115 |
42 | Atorvastatin Restores Lck Expression and Lipid Raft-Associated Signaling in T Cells from Patients with Systemic Lupus Erythematosus | Journal of Immunology | 2006 | 114 |
43 | Cutting Edge: Circulating Plasmablasts Induce the Differentiation of Human T Follicular Helper Cells via IL-6 Production | Journal of Immunology | 2015 | 114 |
44 | In adult onset myositis, the presence of interstitial lung disease and myositis specific/associated antibodies are governed by HLA class II haplotype, rather than by myositis subtype | Arthritis Research and Therapy | 2006 | 110 |
45 | Aryl Hydrocarbon Receptor Contributes to the Transcriptional Program of IL-10-Producing Regulatory B Cells | Cell Reports | 2019 | 107 |
46 | Up-regulation and differential expression of the hyaluronan-binding protein TSG-6 in cartilage and synovium in rheumatoid arthritis and osteoarthritis | Osteoarthritis and Cartilage | 2001 | 105 |
47 | Rituximab in the treatment of inflammatory myopathies: a review | Rheumatology | 2017 | 103 |
48 | The 52 000 MW Ro/SS-A autoantigen in Sjogren's syndrome/systemic lupus erythematosus (Ro52) is an interferon-gamma inducible tripartite motif protein associated with membrane proximal structures | Immunology | 2002 | 101 |
49 | Burden of osteoporosis and fractures | Current Osteoporosis Reports | 2003 | 100 |
50 | Altered lipid raft–associated signaling and ganglioside expression in T lymphocytes from patients with systemic lupus erythematosus | Journal of Clinical Investigation | 2004 | 98 |