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Top Articles

#TitleJournalYearCitations
1Berberine inhibits NLRP3 Inflammasome pathway in human triple-negative breast cancer MDA-MB-231 cellBMC Complementary and Alternative Medicine201977
2A Nanocarrier Skin-Targeted Drug Delivery System using an Ascorbic Acid DerivativePharmaceutical Research201855
3Antidiabetic Drugs for the Risk of Alzheimer Disease in Patients With Type 2 DM Using FAERSAmerican Journal of Alzheimer's Disease and Other Dementias202042
4Effect of antioxidant activity of caffeic acid with cyclodextrins using ground mixture methodAsian Journal of Pharmaceutical Sciences201840
5A new strategy for the passive skin delivery of nanoparticulate, high molecular weight hyaluronic acid prepared by a polyion complex methodScientific Reports201839
6Synthesis of Amide and Ester Derivatives of Cinnamic Acid and Its Analogs: Evaluation of Their Free Radical Scavenging and Monoamine Oxidase and Cholinesterase Inhibitory ActivitiesChemical and Pharmaceutical Bulletin201735
7Changes in brain metabolites related to stress resilience: Metabolomic analysis of the hippocampus in a rat model of depressionBehavioural Brain Research201931
8Changes in sleeping energy metabolism and thermoregulation during menstrual cyclePhysiological Reports202029
9Design, synthesis and evaluation of 2-(indolylmethylidene)-2,3-dihydro-1-benzofuran-3-one and 2-(indolyl)-4H-chromen-4-one derivatives as novel monoamine oxidases inhibitorsBioorganic Chemistry201928
10Characterization of the Dissolution Behavior of Piperine/Cyclodextrins Inclusion ComplexesAAPS PharmSciTech201827
11Evaluation of Antibacterial Activity Expression of the Hinokitiol/Cyclodextrin Complex Against BacteriaACS Omega202026
122-Styrylchromone derivatives as potent and selective monoamine oxidase B inhibitorsBioorganic Chemistry201923
13Development of nanoparticles derived from corn as mass producible bionanoparticles with anticancer activityScientific Reports202122
14Modeling of quantitative relationships between physicochemical properties of active pharmaceutical ingredients and tensile strength of tablets using a boosted treeDrug Development and Industrial Pharmacy201821
15Involvement of Progranulin and Granulin Expression in Inflammatory Responses after Cerebral IschemiaInternational Journal of Molecular Sciences201921
16Chemopreventive and anticancer activity of flavonoids and its possibility for clinical use by combining with conventional chemotherapeutic agentsAmerican Journal of Cancer Research201921
17The Biological Efficacy of Natural Products against Acute and Chronic Inflammatory Diseases in the Oral RegionMedicines (Basel, Switzerland)201820
18Characterization of Inclusion Complex of Coenzyme Q10 with the New Carrier CD-MOF-1 Prepared by Solvent EvaporationAAPS PharmSciTech201820
19Multiple cytotoxic effects of gamabufotalin against human glioblastoma cell line U-87Chemico-Biological Interactions201920
203-(E)-Styryl-2H-chromene derivatives as potent and selective monoamine oxidase B inhibitorsBioorganic Chemistry201819
21Recent Progress of Basic Studies of Natural Products and Their Dental ApplicationMedicines (Basel, Switzerland)201919
22Synthesis and Antimicrobial Activity of 2-Trifluoroacetonylbenzoxazole Ligands and Their Metal ComplexesChemical and Pharmaceutical Bulletin201818
23Inhibitory effect of honokiol on furin-like activity and SARS-CoV-2 infectionJournal of Traditional and Complementary Medicine202218
24Glucose Responsive Rheological Change and Drug Release from a Novel Worm-like Micelle Gel Formed in Cetyltrimethylammonium Bromide/Phenylboronic Acid/Water SystemMolecular Pharmaceutics201816
25Nanoparticulation of hyaluronic acid: A new skin penetration enhancing polyion complex formulation: Mechanism and future potentialMaterialia202016
26Skipping Breakfast for 6 Days Delayed the Circadian Rhythm of the Body Temperature without Altering Clock Gene Expression in Human LeukocytesNutrients202016
27Structural mechanisms for the S‐nitrosylation‐derived protection of mouse galectin‐2 from oxidation‐induced inactivation revealed by NMRFEBS Journal201815
28Quantitative Structure–Cytotoxicity Relationship of 2-StyrylchromonesAnticancer Research201915
29Characterization of Nanoparticles Using DSPE-PEG2000 and SoluplusColloids and Interfaces202015
30Improvement of the Solubility and Evaluation of the Physical Properties of an Inclusion Complex Formed by a New Ferulic Acid Derivative and γ-CyclodextrinACS Omega202015
31Enhancement of Galantamine HBr Skin Permeation Using Sonophoresis and Limonene-Containing PEGylated LiposomesAAPS PharmSciTech201814
32Prediction of tablet characteristics based on sparse modeling for residual stresses simulated by the finite element method incorporating Drucker-Prager cap modelJournal of Drug Delivery Science and Technology201914
33Potential of biocompatible polymeric ultra-thin films, nanosheets, as topical and transdermal drug delivery devicesInternational Journal of Pharmaceutics201914
34JNK and Autophagy Independently Contributed to Cytotoxicity of Arsenite combined With Tetrandrine via Modulating Cell Cycle Progression in Human Breast Cancer CellsFrontiers in Pharmacology202014
35Investigating the Relationship Between Neuronal Cell Death and Early DNA Methylation After Ischemic InjuryFrontiers in Neuroscience202014
36Identification of Galectin-2–Mucin Interaction and Possible Formation of a High Molecular Weight LatticeBiological and Pharmaceutical Bulletin201713
37Development and Optimization of Orally and Topically Applied Liquid Crystal Drug FormulationsJournal of Oleo Science201713
38Evaluation of Solubility Characteristics of a Hybrid Complex of Components of SoyACS Omega201913
39Investigation of factors that cause insulin precipitation and/or amyloid formation in insulin formulationsJournal of Pharmaceutical Health Care and Sciences201913
40Development of Newly Synthesized Chromone Derivatives with High Tumor Specificity against Human Oral Squamous Cell CarcinomaMedicines (Basel, Switzerland)202013
41Physical Properties of an Ionic Liquid Composed of Two Water-Soluble Vitamins and Enhanced Skin Permeation of Both VitaminsPharmaceutics202013
42Comparative assessment of 24-hr primary skin irritation test and human patch test data with <i>in vitro</i> skin irritation tests according to OECD Test Guideline 439 (for quasi-drugs in Japan)Journal of Toxicological Sciences201812
43Assessment of the Physical Properties of Inclusion Complexes of Forchlorfenuron and γ-Cyclodextrin Derivatives and Their Promotion of Plant GrowthACS Omega201812
44Quantitative Structure–Cytotoxicity Relationship of Pyrano[4,3-b]chromonesAnticancer Research201812
45Design of a Topically Applied Gel Spray Formulation with Ivermectin Using a Novel Low Molecular Weight Gelling Agent, Palmitoyl-Glycine-Histidine, to Treat ScabiesChemical and Pharmaceutical Bulletin201812
46Effects of Temperature and Humidity on the Skin Permeation of Hydrophilic and Hydrophobic DrugsAAPS PharmSciTech201912
47Further Quantitative Structure–Cytotoxicity Relationship Analysis of 3-StyrylchromonesAnticancer Research202012
48Quantitative Structure–Cytotoxicity Relationship of Newly Synthesized Piperic Acid EstersAnticancer Research201712
49Re-evaluation of Culture Condition of PC12 and SH-SY5Y Cells Based on Growth Rate and Amino Acid ConsumptionIn Vivo201712
50Establishment of a Direct-Injection Electron Ionization-Mass Spectrometry Metabolomics Method and Its Application to Lichen ProfilingAnalytical Chemistry201711