| # | Title | Journal | Year | Citations |
|---|
| 1 | A comprehensive survey of genomic alterations in gastric cancer reveals systematic patterns of molecular exclusivity and co-occurrence among distinct therapeutic targets | Gut | 2012 | 562 |
| 2 | Pan-Asian adapted ESMO consensus guidelines for the management of patients with metastatic colorectal cancer: a JSMO–ESMO initiative endorsed by CSCO, KACO, MOS, SSO and TOS | Annals of Oncology | 2018 | 432 |
| 3 | Afatinib versus gefitinib in patients with EGFR mutation-positive advanced non-small-cell lung cancer: overall survival data from the phase IIb LUX-Lung 7 trial | Annals of Oncology | 2017 | 425 |
| 4 | Lineage-dependent gene expression programs influence the immune landscape of colorectal cancer | Nature Genetics | 2020 | 380 |
| 5 | Ipatasertib plus paclitaxel versus placebo plus paclitaxel as first-line therapy for metastatic triple-negative breast cancer (LOTUS): a multicentre, randomised, double-blind, placebo-controlled, phase 2 trial | Lancet Oncology, The | 2017 | 377 |
| 6 | Oncogenic Pathway Combinations Predict Clinical Prognosis in Gastric Cancer | PLoS Genetics | 2009 | 354 |
| 7 | Management of Patients with Advanced Prostate Cancer: Report of the Advanced Prostate Cancer Consensus Conference 2019 | European Urology | 2020 | 278 |
| 8 | The Global State of the Genetic Counseling Profession | European Journal of Human Genetics | 2019 | 215 |
| 9 | Adoptive T-cell Transfer and Chemotherapy in the First-line Treatment of Metastatic and/or Locally Recurrent Nasopharyngeal Carcinoma | Molecular Therapy | 2014 | 185 |
| 10 | Nivolumab in advanced hepatocellular carcinoma: Sorafenib-experienced Asian cohort analysis | Journal of Hepatology | 2019 | 180 |
| 11 | Progression-Free and Overall Survival in ALK-Positive NSCLC Patients Treated with Sequential Crizotinib and Ceritinib | Clinical Cancer Research | 2015 | 173 |
| 12 | Genome-wide association study identifies five new susceptibility loci for primary angle closure glaucoma | Nature Genetics | 2016 | 147 |
| 13 | Comprehensive genomic meta-analysis identifies intra-tumoural stroma as a predictor of survival in patients with gastric cancer | Gut | 2013 | 139 |
| 14 | Antiviral treatment in patients with indolent B-cell lymphomas associated with HCV infection: a study of the Fondazione Italiana Linfomi | Annals of Oncology | 2014 | 133 |
| 15 | CheckMate 040 cohort 5: A phase I/II study of nivolumab in patients with advanced hepatocellular carcinoma and Child-Pugh B cirrhosis | Journal of Hepatology | 2021 | 127 |
| 16 | The spatial organization of intra-tumour heterogeneity and evolutionary trajectories of metastases in hepatocellular carcinoma | Nature Communications | 2017 | 117 |
| 17 | Understanding the Psychological Impact of COVID-19 Pandemic on Patients With Cancer, Their Caregivers, and Health Care Workers in Singapore | JCO Global Oncology | 2020 | 95 |
| 18 | An International Collaborative Standardizing a Comprehensive Patient-Centered Outcomes Measurement Set for Colorectal Cancer | JAMA Oncology | 2017 | 94 |
| 19 | Integrated epigenomics identifiesBMP4as a modulator of cisplatin sensitivity in gastric cancer | Gut | 2013 | 88 |
| 20 | Pembrolizumab-induced Stevens–Johnson syndrome in non-melanoma patients | European Journal of Cancer | 2017 | 88 |
| 21 | Intraperitoneal immunotherapy with T cells stably and transiently expressing anti-EpCAM CAR in xenograft models of peritoneal carcinomatosis | Oncotarget | 2017 | 84 |
| 22 | Epstein-Barr virus-associated primary nodal T/NK-cell lymphoma shows a distinct molecular signature and copy number changes | Haematologica | 2018 | 82 |
| 23 | Combinational Immunotherapy for Hepatocellular Carcinoma: Radiotherapy, Immune Checkpoint Blockade and Beyond | Frontiers in Immunology | 2020 | 79 |
| 24 | Breast cancer risk and clinical implications for germline PTEN mutation carriers | Breast Cancer Research and Treatment | 2017 | 78 |
| 25 | Priorities for the global advancement of care for older adults with cancer: an update of the International Society of Geriatric Oncology Priorities Initiative | Lancet Oncology, The | 2021 | 71 |
| 26 | Body Mass Index, Diabetes and Intrahepatic Cholangiocarcinoma Risk: The Liver Cancer Pooling Project and Meta-analysis | American Journal of Gastroenterology | 2018 | 70 |
| 27 | Clinical Outcomes with Multikinase Inhibitors after Progression on First-Line Atezolizumab plus Bevacizumab in Patients with Advanced Hepatocellular Carcinoma: A Multinational Multicenter Retrospective Study | Liver Cancer | 2021 | 66 |
| 28 | Blood neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios are independent prognostic factors for surgically resected gastrointestinal stromal tumors | Surgery | 2016 | 63 |
| 29 | EGFR Mutation Subtypes Influence Survival Outcomes following First-Line Gefitinib Therapy in Advanced Asian NSCLC Patients | Journal of Thoracic Oncology | 2017 | 57 |
| 30 | Afatinib as First-line Treatment of Older Patients With EGFR Mutation-Positive Non-Small-Cell Lung Cancer: Subgroup Analyses of the LUX-Lung 3, LUX-Lung 6, and LUX-Lung 7 Trials | Clinical Lung Cancer | 2018 | 56 |
| 31 | Radioembolisation with Y90-resin microspheres followed by nivolumab for advanced hepatocellular carcinoma (CA 209-678): a single arm, single centre, phase 2 trial | The Lancet Gastroenterology and Hepatology | 2021 | 56 |
| 32 | Homologous Recombination Deficiency: Cancer Predispositions and Treatment Implications | Oncologist | 2021 | 53 |
| 33 | Single‐cell profiling approaches to probing tumor heterogeneity | International Journal of Cancer | 2016 | 52 |
| 34 | Germline Mutations in Cancer Predisposition Genes are Frequent in Sporadic Sarcomas | Scientific Reports | 2017 | 52 |
| 35 | Management of Patients with Advanced Prostate Cancer: Report from the Advanced Prostate Cancer Consensus Conference 2021 | European Urology | 2022 | 51 |
| 36 | Population pharmacokinetics and pharmacodynamics of oral etoposide | British Journal of Clinical Pharmacology | 2001 | 48 |
| 37 | Patient-specific hepatocyte-like cells derived from induced pluripotent stem cells model pazopanib-mediated hepatotoxicity | Scientific Reports | 2017 | 47 |
| 38 | Genome-wide association study of B cell non-Hodgkin lymphoma identifies 3q27 as a susceptibility locus in the Chinese population | Nature Genetics | 2013 | 43 |
| 39 | Management of epidermal growth factor receptor tyrosine kinase inhibitor‐related cutaneous and gastrointestinal toxicities | Asia-Pacific Journal of Clinical Oncology | 2018 | 43 |
| 40 | OA02.01 Efficacy and Safety of Entrectinib in Locally Advanced or Metastatic ROS1 Fusion-Positive Non-Small Cell Lung Cancer (NSCLC) | Journal of Thoracic Oncology | 2018 | 42 |
| 41 | Pan-Asian adapted ESMO Clinical Practice Guidelines for the diagnosis treatment and follow-up of patients with localised colon cancer | Annals of Oncology | 2021 | 42 |
| 42 | A phase 2 study of BGJ398 in patients (pts) with advanced or metastatic FGFR-altered cholangiocarcinoma (CCA) who failed or are intolerant to platinum-based chemotherapy. | Journal of Clinical Oncology | 2016 | 42 |
| 43 | Precision medicine in heritable cancer: when somatic tumour testing and germline mutations meet | Npj Genomic Medicine | 2016 | 41 |
| 44 | Continued Response to One Dose of Nivolumab Complicated by Myasthenic Crisis and Myositis | Journal of Thoracic Oncology | 2017 | 38 |
| 45 | Are preoperative blood neutrophil‐to‐lymphocyte and platelet‐to‐lymphocyte ratios useful in predicting malignancy in surgically‐treated mucin‐producing pancreatic cystic neoplasms? | Journal of Surgical Oncology | 2015 | 37 |
| 46 | Biological significance and prognostic relevance of peripheral blood neutrophil-to-lymphocyte ratio in soft tissue sarcoma | Scientific Reports | 2018 | 37 |
| 47 | Systematic Review and Meta-Analysis of Randomised Trials to Ascertain Fatal Gastrointestinal Bleeding Events Attributable to Preventive Low-Dose Aspirin: No Evidence of Increased Risk | PLoS ONE | 2016 | 37 |
| 48 | Asian Thoracic Oncology Research Group Expert Consensus Statement on Optimal Management of Stage III NSCLC | Journal of Thoracic Oncology | 2020 | 34 |
| 49 | Somatostatin receptor 2 expression in nasopharyngeal cancer is induced by Epstein Barr virus infection: impact on prognosis, imaging and therapy | Nature Communications | 2021 | 34 |
| 50 | Results of the GEOMETRY mono-1 phase II study for evaluation of the MET inhibitor capmatinib (INC280) in patients (pts) with METΔex14 mutated advanced non-small cell lung cancer (NSCLC) | Annals of Oncology | 2018 | 33 |
