| RAC1 activation mediates Twist1-induced cancer cell migration | Nature Cell Biology | 2012 | 183 |
| Trifluoperazine, an antipsychotic agent, inhibits cancer stem cell growth and overcomes drug resistance of lung cancer | American Journal of Respiratory and Critical Care Medicine | 2012 | 137 |
| Dovitinib induces apoptosis and overcomes sorafenib resistance in hepatocellular carcinoma through SHP-1-mediated inhibition of STAT3 | Molecular Cancer Therapeutics | 2012 | 103 |
| A nation-wide analysis of venous thromboembolism in 497,180 cancer patients with the development and validation of a risk-stratification scoring system | Thrombosis and Haemostasis | 2012 | 80 |
| BRAF mutation is a prognostic biomarker for colorectal liver metastasectomy | Journal of Surgical Oncology | 2012 | 69 |
| Connective tissue growth factor modulates oral squamous cell carcinoma invasion by activating a miR-504/FOXP1 signalling | Oncogene | 2012 | 64 |
| Atrial fibrillation and the risk of ischemic stroke: does it still matter in patients with a CHA2DS2-VASc score of 0 or 1? | Stroke | 2012 | 62 |
| Blockade of STAT3 activation by sorafenib derivatives through enhancing SHP-1 phosphatase activity | European Journal of Medicinal Chemistry | 2012 | 61 |
| Treatment for T1-2 oral squamous cell carcinoma with or without perineural invasion: neck dissection and postoperative adjuvant therapy | Annals of Surgical Oncology | 2012 | 54 |
| CIP2A is a predictor of poor prognosis in colon cancer | Journal of Gastrointestinal Surgery | 2012 | 53 |
| Outcome after percutaneous cholecystostomy for acute cholecystitis: a single-center experience | Journal of Gastrointestinal Surgery | 2012 | 51 |
| Epigallocathechin gallate, polyphenol present in green tea, inhibits stem-like characteristics and epithelial-mesenchymal transition in nasopharyngeal cancer cell lines | BMC Complementary and Alternative Medicine | 2012 | 47 |
| Overexpression of Akt1 enhances adipogenesis and leads to lipoma formation in zebrafish | PLoS ONE | 2012 | 47 |
| Duloxetine improves oxaliplatin-induced neuropathy in patients with colorectal cancer: an open-label pilot study | Supportive Care in Cancer | 2012 | 46 |
| Inhibition of Bcl-2 improves effect of LCL161, a SMAC mimetic, in hepatocellular carcinoma cells | Biochemical Pharmacology | 2012 | 42 |
| A novel obatoclax derivative, SC-2001, induces apoptosis in hepatocellular carcinoma cells through SHP-1-dependent STAT3 inactivation | Cancer Letters | 2012 | 41 |
| Change in treatment strategy for intracranial germinoma: long-term follow-up experience at a single institute | Cancer | 2012 | 37 |
| AMP-activated protein kinase mediates erythropoietin-induced activation of endothelial nitric oxide synthase | Journal of Cellular Physiology | 2012 | 36 |
| Dovitinib sensitizes hepatocellular carcinoma cells to TRAIL and tigatuzumab, a novel anti-DR5 antibody, through SHP-1-dependent inhibition of STAT3 | Biochemical Pharmacology | 2012 | 34 |
| Clinicopathologic features and prognostic analysis of MSI-high colon cancer | International Journal of Colorectal Disease | 2012 | 30 |
| Development of erlotinib derivatives as CIP2A-ablating agents independent of EGFR activity | Bioorganic and Medicinal Chemistry | 2012 | 28 |
| Epidermal growth factor receptor R521K polymorphism shows favorable outcomes in KRAS wild-type colorectal cancer patients treated with cetuximab-based chemotherapy | Cancer Science | 2012 | 25 |
| Impact of pulmonary and extrapulmonary tuberculosis infection in kidney transplantation: a nationwide population-based study in Taiwan | Transplant Infectious Disease | 2012 | 24 |
| Long-term mortality of patients with septic ocular or central nervous system complications from pyogenic liver abscess: a population-based study | PLoS ONE | 2012 | 23 |
| Prior exercise training alleviates the lung inflammation induced by subsequent exposure to environmental cigarette smoke | Acta Physiologica | 2012 | 19 |
