| # | Title | Journal | Year | Citations |
|---|
| 1 | In-Hospital Mortality in Patients With Acute Decompensated Heart Failure Requiring Intravenous Vasoactive Medications | Journal of the American College of Cardiology | 2005 | 712 |
| 2 | Gender disparities in the diagnosis and treatment of non–ST-segment elevation acute coronary syndromes | Journal of the American College of Cardiology | 2005 | 569 |
| 3 | Oral Anticoagulant Therapy Prescription in Patients With Atrial Fibrillation Across the Spectrum of Stroke Risk | JAMA Cardiology | 2016 | 249 |
| 4 | Chronic Oral Study of Myosin Activation to Increase Contractility in Heart Failure (COSMIC-HF): a phase 2, pharmacokinetic, randomised, placebo-controlled trial | Lancet, The | 2016 | 229 |
| 5 | Multiple Metabolic Syndrome Is Associated With Lower Heart Rate Variability: The Atherosclerosis Risk in Communities Study | Diabetes Care | 1998 | 196 |
| 6 | Therapeutic strategies for thrombosis: new targets and approaches | Nature Reviews Drug Discovery | 2020 | 188 |
| 7 | Accuracy of Cuff-Measured Blood Pressure | Journal of the American College of Cardiology | 2017 | 186 |
| 8 | Sent to Destroy | Circulation Research | 2010 | 181 |
| 9 | Exposure to Particulate Matter, Volatile Organic Compounds, and Other Air Pollutants Inside Patrol Cars | Environmental Science & Technology | 2003 | 176 |
| 10 | Targeted repair of heart injury by stem cells fused with platelet nanovesicles | Nature Biomedical Engineering | 2018 | 161 |
| 11 | Minimally invasive delivery of therapeutic agents by hydrogel injection into the pericardial cavity for cardiac repair | Nature Communications | 2021 | 155 |
| 12 | Effectiveness and Safety of Dabigatran and Warfarin in Real‐World US Patients With Non‐Valvular Atrial Fibrillation: A Retrospective Cohort Study | Journal of the American Heart Association | 2015 | 126 |
| 13 | Hybrid epicardial-endocardial ablation using a pericardioscopic technique for the treatment of atrial fibrillation | Heart Rhythm | 2013 | 109 |
| 14 | The pH paradox in ischemia-reperfusion injury to cardiac myocytes | Heart Rhythm | 1996 | 106 |
| 15 | Acute effects of monounsaturated fatty acids with and without omega-3 fatty acids on vascular reactivity in individuals with type 2 diabetes | Diabetologia | 2005 | 100 |
| 16 | Electrophysiologic Changes in Ischemic Ventricular Myocardium: I. Influence of Ionic, Metabolic, and Energetic Changes | Journal of Cardiovascular Electrophysiology | 1995 | 95 |
| 17 | Multisite Investigation of Strategies for the Implementation of CYP2C19 Genotype‐Guided Antiplatelet Therapy | Clinical Pharmacology and Therapeutics | 2018 | 94 |
| 18 | Thrombolysis and Adjunctive Therapy in Acute Myocardial Infarction | Chest | 2004 | 87 |
| 19 | Safety and Performance of Targeted Renal Therapy: The Be-RITe! Registry | Journal of Endovascular Therapy | 2009 | 87 |
| 20 | Bridging the treatment gap | American Journal of Cardiology | 2000 | 86 |
| 21 | Doxorubicin Exposure Causes Subacute Cardiac Atrophy Dependent on the Striated Muscle–Specific Ubiquitin Ligase MuRF1 | Circulation: Heart Failure | 2019 | 79 |
| 22 | A simple prediction rule for significant renal artery stenosis in patients undergoing cardiac catheterization | American Heart Journal | 2005 | 75 |
| 23 | Pulmonary artery catheterization in acute coronary syndromes: Insights from the GUSTO IIb and GUSTO III trials | American Journal of Medicine | 2005 | 75 |
| 24 | A semiquantitative metric for evaluating clinical actionability of incidental or secondary findings from genome-scale sequencing | Genetics in Medicine | 2016 | 74 |
| 25 | Association of Public Health Initiatives With Outcomes for Out-of-Hospital Cardiac Arrest at Home and in Public Locations | JAMA Cardiology | 2017 | 73 |
| 26 | Heart rate: a prognostic factor and therapeutic target in chronic heart failure. The distinct roles of drugs with heart rate‐lowering properties | European Journal of Heart Failure | 2014 | 70 |
| 27 | Utility of Growth Differentiation Factor-15, A Marker of Oxidative Stress and Inflammation, in Chronic Heart Failure | JACC: Heart Failure | 2017 | 69 |
| 28 | Reproducibility of Masked Hypertension in Adults With Untreated Borderline Office Blood Pressure: Comparison of Ambulatory and Home Monitoring | American Journal of Hypertension | 2010 | 68 |
| 29 | Frequency and Clinical Implications of Discordant Creatine Kinase-MB and Troponin Measurements in Acute Coronary Syndromes | Journal of the American College of Cardiology | 2006 | 67 |
| 30 | Silent Myocardial Infarction and Long-Term Risk of Heart Failure | Journal of the American College of Cardiology | 2018 | 66 |
| 31 | COVID-19: Understanding Inter-Individual Variability and Implications for Precision Medicine | Mayo Clinic Proceedings | 2021 | 62 |
| 32 | Injection of ROS‐Responsive Hydrogel Loaded with Basic Fibroblast Growth Factor into the Pericardial Cavity for Heart Repair | Advanced Functional Materials | 2021 | 60 |
| 33 | Temporal Trends in Prevalence and Prognostic Implications of Comorbidities Among Patients With Acute Decompensated Heart Failure | Circulation | 2020 | 59 |
| 34 | Differences in flurbiprofen pharmacokinetics between CYP2C9*1/*1, *1/*2, and *1/*3 genotypes | European Journal of Clinical Pharmacology | 2003 | 58 |
| 35 | Effect of Statin Use on Acute Kidney Injury Risk Following Coronary Artery Bypass Grafting | American Journal of Cardiology | 2013 | 56 |
| 36 | Correlation of Ischemia-Induced Extracellular and Intracellular Ion Changes to Cell-to-Cell Electrical Uncoupling in Isolated Blood-Perfused Rabbit Hearts | Circulation | 1996 | 54 |
| 37 | Care of non-ST-segment elevation patients: Insights from the crusade national quality improvement initiative | American Heart Journal | 2004 | 53 |
| 38 | In vivo and in vitro testing of microelectronically fabricated planar sensors designed for applications in cardiology | Fresenius' Journal of Analytical Chemistry | 1993 | 49 |
| 39 | BMPER is a conserved regulator of hematopoietic and vascular development in zebrafish | Journal of Molecular and Cellular Cardiology | 2007 | 49 |
| 40 | Antiplatelet therapies and the role of antiplatelet resistance in acute coronary syndrome | Thrombosis Research | 2009 | 48 |
| 41 | Cardiovascular physiology in the older adults | Journal of Geriatric Cardiology | 2015 | 48 |
| 42 | Clinical treatment of dyslipidemia: practice patterns and missed opportunities | American Journal of Cardiology | 2000 | 46 |
| 43 | Biological correlates of day-to-day variation in flow-mediated dilation in individuals with Type 2 diabetes: a study of test?retest reliability | Diabetologia | 2004 | 46 |
| 44 | Polymorphic metabolizing genes and susceptibility to atherosclerosis among cigarette smokers | Environmental and Molecular Mutagenesis | 2002 | 44 |
| 45 | Dose response characterization of the association of serum digoxin concentration with mortality outcomes in the Digitalis Investigation Group trial | European Journal of Heart Failure | 2016 | 44 |
| 46 | Coping styles in heart failure patients with depressive symptoms | Journal of Psychosomatic Research | 2009 | 42 |
| 47 | Myocardial ischemia during daily activities: The importance of increased myocardial oxygen demand | Journal of the American College of Cardiology | 1991 | 41 |
| 48 | Placenta growth factor in sickle cell disease: association with hemolysis and inflammation | Blood | 2010 | 41 |
| 49 | Frequency and clinical outcomes of CYP2C19 genotype-guided escalation and de-escalation of antiplatelet therapy in a real-world clinical setting | Genetics in Medicine | 2020 | 41 |
| 50 | Tolerability of the Oscar 2 ambulatory blood pressure monitor among research participants: a cross-sectional repeated measures study | BMC Medical Research Methodology | 2011 | 40 |
