| # | Title | Journal | Year | Citations |
|---|
| 1 | Genetic studies of body mass index yield new insights for obesity biology | Nature | 2015 | 3,823 |
| 2 | Discovery and refinement of loci associated with lipid levels | Nature Genetics | 2013 | 2,641 |
| 3 | Defining the role of common variation in the genomic and biological architecture of adult human height | Nature Genetics | 2014 | 1,818 |
| 4 | Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis | Nature Genetics | 2010 | 1,631 |
| 5 | Genome sequence and analysis of the Irish potato famine pathogen Phytophthora infestans | Nature | 2009 | 1,405 |
| 6 | New genetic loci link adipose and insulin biology to body fat distribution | Nature | 2015 | 1,328 |
| 7 | Genetic mechanisms of critical illness in COVID-19 | Nature | 2021 | 1,014 |
| 8 | The SR protein family of splicing factors: master regulators of gene expression | Biochemical Journal | 2009 | 934 |
| 9 | Mapping genomic loci implicates genes and synaptic biology in schizophrenia | Nature | 2022 | 929 |
| 10 | Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits | Nature Genetics | 2018 | 924 |
| 11 | Common variants associated with plasma triglycerides and risk for coronary artery disease | Nature Genetics | 2013 | 754 |
| 12 | Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways | Nature Genetics | 2012 | 746 |
| 13 | Eleven grand challenges in single-cell data science | Genome Biology | 2020 | 742 |
| 14 | New loci associated with kidney function and chronic kidney disease | Nature Genetics | 2010 | 710 |
| 15 | The BioMart community portal: an innovative alternative to large, centralized data repositories | Nucleic Acids Research | 2015 | 682 |
| 16 | Genome-wide association studies establish that human intelligence is highly heritable and polygenic | Molecular Psychiatry | 2011 | 571 |
| 17 | RIF1 Is Essential for 53BP1-Dependent Nonhomologous End Joining and Suppression of DNA Double-Strand Break Resection | Molecular Cell | 2013 | 543 |
| 18 | Genome-wide association study identifies five loci associated with lung function | Nature Genetics | 2010 | 518 |
| 19 | A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3 | Nature Genetics | 2008 | 514 |
| 20 | Runs of homozygosity: windows into population history and trait architecture | Nature Reviews Genetics | 2018 | 497 |
| 21 | Whole‐genome sequencing identifies EN1 as a determinant of bone density and fracture | Nature | 2015 | 483 |
| 22 | Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies | Nature Genetics | 2010 | 445 |
| 23 | Orphan CpG Islands Identify Numerous Conserved Promoters in the Mammalian Genome | PLoS Genetics | 2010 | 445 |
| 24 | High Throughput Isolation and Glycosylation Analysis of IgG–Variability and Heritability of the IgG Glycome in Three Isolated Human Populations | Molecular and Cellular Proteomics | 2011 | 443 |
| 25 | Visceral and subcutaneous fat have different origins and evidence supports a mesothelial source | Nature Cell Biology | 2014 | 422 |
| 26 | Mechanism and regulation of the nonsense-mediated decay pathway | Nucleic Acids Research | 2016 | 415 |
| 27 | Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure | Nature Genetics | 2011 | 403 |
| 28 | Post-transcriptional control of miRNA biogenesis | Rna | 2019 | 390 |
| 29 | Multi-system neurological disease is common in patients with OPA1 mutations | Brain | 2010 | 385 |
| 30 | Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases | JAMA Oncology | 2017 | 376 |
| 31 | Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function | Nature Genetics | 2011 | 367 |
| 32 | The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals | Nature Genetics | 2016 | 362 |
| 33 | New insights into the aetiology of colorectal cancer from genome-wide association studies | Nature Reviews Genetics | 2009 | 355 |
| 34 | The power of genetic diversity in genome-wide association studies of lipids | Nature | 2021 | 353 |
| 35 | Structure, Dynamics, Assembly, and Evolution of Protein Complexes | Annual Review of Biochemistry | 2015 | 351 |
| 36 | Genetic contributions to variation in general cognitive function: a meta-analysis of genome-wide association studies in the CHARGE consortium (N=53 949) | Molecular Psychiatry | 2015 | 344 |
| 37 | Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis | PLoS Medicine | 2017 | 341 |
| 38 | The trans-ancestral genomic architecture of glycemic traits | Nature Genetics | 2021 | 341 |
| 39 | High Rate of Recurrent De Novo Mutations in Developmental and Epileptic Encephalopathies | American Journal of Human Genetics | 2017 | 337 |
| 40 | How do chemotherapeutic agents damage the ovary? | Human Reproduction Update | 2012 | 335 |
| 41 | The calpain system and cancer | Nature Reviews Cancer | 2011 | 333 |
| 42 | Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals | Nature Metabolism | 2020 | 327 |
| 43 | Posttranscriptional Regulation of miRNAs Harboring Conserved Terminal Loops | Molecular Cell | 2008 | 316 |
| 44 | The FERM domain: organizing the structure and function of FAK | Nature Reviews Molecular Cell Biology | 2010 | 314 |
| 45 | Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways | Nature Genetics | 2012 | 303 |
| 46 | Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels | Nature Communications | 2018 | 295 |
| 47 | A framework for the development of guidelines for the management of glucocorticoid-induced osteoporosis | Osteoporosis International | 2012 | 291 |
| 48 | Meta-analysis of Genome-wide Association Studies for Neuroticism, and the Polygenic Association With Major Depressive Disorder | JAMA Psychiatry | 2015 | 289 |
| 49 | Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization | Nature Genetics | 2014 | 281 |
| 50 | Beyond Gene Discovery in Inflammatory Bowel Disease: The Emerging Role of Epigenetics | Gastroenterology | 2013 | 275 |
