| # | Title | Journal | Year | Citations |
|---|
| 1 | Identification of two related pentapeptides from the brain with potent opiate agonist activity | Nature | 1975 | 3,754 |
| 2 | Sequence and structure of a human glucose transporter | Science | 1985 | 1,522 |
| 3 | Amyotrophic lateral sclerosis and structural defects in Cu,Zn superoxide dismutase | Science | 1993 | 1,499 |
| 4 | Early-onset Alzheimer's disease caused by mutations at codon 717 of the β-amyloid precursor protein gene | Nature | 1991 | 1,202 |
| 5 | Glycoprotein Structure Determination by Mass Spectrometry | Science | 2001 | 547 |
| 6 | Identification of xanthurenic acid as the putative inducer of malaria development in the mosquito | Nature | 1998 | 530 |
| 7 | Inhibition of NF- B DNA Binding by Nitric Oxide | Nucleic Acids Research | 1996 | 500 |
| 8 | Polo, a mitotic mutant of Drosophila displaying abnormal spindle poles | Journal of Cell Science | 1988 | 496 |
| 9 | Cryo-electron microscopy structure of an SH3 amyloid fibril and model of the molecular packing | EMBO Journal | 1999 | 487 |
| 10 | Structure of locust adipokinetic hormone, a neurohormone that regulates lipid utilisation during flight | Nature | 1976 | 484 |
| 11 | Isolation and characterization of human calcitonin gene-related peptide | Nature | 1984 | 447 |
| 12 | Identification of a functional respiratory complex in chloroplasts through analysis of tobacco mutants containing disrupted plastid ndh genes | EMBO Journal | 1998 | 446 |
| 13 | Structure of slow-reacting substance of anaphylaxis from guinea-pig lung | Nature | 1980 | 430 |
| 14 | Movement of internalized ligand–receptor complexes along a continuous endosomal reticulum | Nature | 1990 | 416 |
| 15 | Glutamate, GABA and epilepsy | Progress in Neurobiology | 1995 | 400 |
| 16 | High Sensitivity Collisionally-activated Decomposition Tandem Mass Spectrometry on a Novel Quadrupole/Orthogonal-acceleration Time-of-flight Mass Spectrometer | Progress in Neurobiology | 1996 | 398 |
| 17 | Metabolism of the heart in health and disease. Part I | American Heart Journal | 1968 | 376 |
| 18 | GLUTAMINE?A MAJOR SUBSTRATE FOR NERVE ENDINGS | Journal of Neurochemistry | 1978 | 373 |
| 19 | Chemical structure of the morphogen differentiation inducing factor from Dictyostelium discoideum | Nature | 1987 | 373 |
| 20 | Antimicrobial Actions of the Nadph Phagocyte Oxidase and Inducible Nitric Oxide Synthase in Experimental Salmonellosis. II. Effects on Microbial Proliferation and Host Survival in Vivo | Journal of Experimental Medicine | 2000 | 364 |
| 21 | F.A.B.-Mass Spectrometry of Carbohydrates | Advances in Carbohydrate Chemistry and Biochemistry | 1987 | 330 |
| 22 | Acceptors for botulinum neurotoxin reside on motor nerve terminals and mediate its internalization | Nature | 1984 | 318 |
| 23 | Repetitive Action Potentials in Isolated Nerve Terminals in the Presence of 4-Aminopyridine: Effects on Cytosolic Free Ca2+and Glutamate Release | Journal of Neurochemistry | 1989 | 298 |
| 24 | Mutants of Escherichia coli heat-labile toxin lacking ADP-ribosyltransferase activity act as nontoxic, mucosal adjuvants. | Proceedings of the National Academy of Sciences of the United States of America | 1995 | 298 |
| 25 | Dosage-Sensitive and Complementary Functions of Roundabout and Commissureless Control Axon Crossing of the CNS Midline | Neuron | 1998 | 283 |
| 26 | Mucosal vaccines: non toxic derivatives of LT and CT as mucosal adjuvants | Vaccine | 2001 | 277 |
| 27 | Characterization of carbohydrate structural features recognized by anti-arabinogalactan-protein monoclonal antibodies | Glycobiology | 1996 | 273 |
| 28 | Molecular recognition and the future of monoclonal antibodies | Nature | 1982 | 272 |
| 29 | Enkephalin-like material elevated in ventricular cerebrospinal fluid of pain patients after analgetic focal stimulation | Science | 1978 | 270 |
| 30 | α-Latrotoxin Receptor, Latrophilin, Is a Novel Member of the Secretin Family of G Protein-coupled Receptors | Journal of Biological Chemistry | 1997 | 267 |
| 31 | Pseudomonic Acid: an Antibiotic produced by Pseudomonas fluorescens | Nature | 1971 | 266 |
| 32 | Cell fate choices and the expression of Notch, Delta and Serrate homologues in the chick inner ear: parallels with Drosophila sense-organ development | Development (Cambridge) | 1998 | 259 |
| 33 | Meningococcal pilin: a glycoprotein substituted with digalactosyl 2,4-diacetamido-2,4,6-trideoxyhexose | Molecular Microbiology | 1995 | 256 |
| 34 | A multimer model for P680, the primary electron donor of photosystem II. | Proceedings of the National Academy of Sciences of the United States of America | 1995 | 251 |
| 35 | Botulinum Neurotoxin C1 Cleaves both Syntaxin and SNAP-25 in Intact and Permeabilized Chromaffin Cells: Correlation with Its Blockade of Catecholamine Release | Biochemistry | 1996 | 249 |
| 36 | Fast atom bombardment: A new mass spectrometric method for peptide sequence analysis | Biochemical and Biophysical Research Communications | 1981 | 246 |
| 37 | Development of macroglial cells in rat cerebellum II. An in situ immunohistochemical study of oligodendroglial lineage from precursor to mature myelinating cell | Development (Cambridge) | 1988 | 242 |
| 38 | [8] Mass spectrometry of carbohydrate-containing biopolymers | Methods in Enzymology | 1994 | 227 |
| 39 | polo, a mitotic mutant of Drosophila displaying abnormal spindle poles | Journal of Cell Science | 1988 | 223 |
| 40 | The effects of purified botulinum neurotoxin type A on cholinergic, adrenergic and non-adrenergic, atropine-resistant autonomic neuromuscular transmission | Neuroscience | 1982 | 218 |
| 41 | Nuclear and cytoplasmic mitotic cycles continue in Drosophila embryos in which DNA synthesis is inhibited with aphidicolin. | Journal of Cell Biology | 1988 | 218 |
| 42 | Human calcitonin gene related peptide: a potent endogenous vasodilator in man | Clinical Science | 1986 | 209 |
| 43 | Inhibition of isoleucyl-transfer ribonucleic acid synthetase in Echerichia coli by pseudomonic acid | Biochemical Journal | 1978 | 207 |
| 44 | On glutaminase activity in mammalian synaptosomes | Brain Research | 1976 | 203 |
| 45 | The sfr6 Mutation in Arabidopsis Suppresses Low-Temperature Induction of Genes Dependent on the CRT/DRE Sequence Motif | Plant Cell | 1999 | 203 |
| 46 | A lethal role for lipid A inSalmonellainfections | Molecular Microbiology | 1998 | 201 |
| 47 | Ultrastructural damage associated with reoxygenation of the anoxic myocardium | Journal of Molecular and Cellular Cardiology | 1975 | 199 |
| 48 | Arrangements and rearrangements of sequences flanking the two types of rDNA insertion in D. melanogaster | Nature | 1981 | 194 |
| 49 | Characterisation of triplet states in isolated Photosystem II reaction centres: Oxygen quenching as a mechanism for photodamage | Biochimica Et Biophysica Acta - Bioenergetics | 1990 | 194 |
| 50 | Inositol Phosphate Capping of the Nonreducing Termini of Lipoarabinomannan from Rapidly Growing Strains of Mycobacterium | Journal of Biological Chemistry | 1995 | 190 |
