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Section of Cell Biology and Functional Genomics
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top-articles
Section of Cell Biology and Functional Genomics
123
(top 1%)
papers
4.3K
(top 1%)
citations
39
(top 1%)
h
-index
62
(top 1%)
g
-index
151
all documents
5.2K
doc citations
1.1K
citing journals
Top Articles
#
Title
Journal
Year
Citations
1
The Role of Oxidative Stress and Hypoxia in Pancreatic Beta-Cell Dysfunction in Diabetes Mellitus
Antioxidants and Redox Signaling
2017
433
2
Beta Cell Hubs Dictate Pancreatic Islet Responses to Glucose
Cell Metabolism
2016
370
3
Targeting GLP-1 receptor trafficking to improve agonist efficacy
Nature Communications
2018
162
4
Zinc and diabetes
Archives of Biochemistry and Biophysics
2016
131
5
Systems biology of the IMIDIA biobank from organ donors and pancreatectomised patients defines a novel transcriptomic signature of islets from individuals with type 2 diabetes
Diabetologia
2018
131
6
The zinc transporter ZIP12 regulates the pulmonary vascular response to chronic hypoxia
Nature
2015
113
7
Photoswitchable diacylglycerols enable optical control of protein kinase C
Nature Chemical Biology
2016
112
8
The α-cell in diabetes mellitus
Nature Reviews Endocrinology
2018
103
9
Nicotinamide riboside kinases display redundancy in mediating nicotinamide mononucleotide and nicotinamide riboside metabolism in skeletal muscle cells
Molecular Metabolism
2017
96
10
An essential role for the Zn2+ transporter ZIP7 in B cell development
Nature Immunology
2019
92
11
Super-resolution microscopy compatible fluorescent probes reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics
Nature Communications
2020
88
12
eZinCh-2: A Versatile, Genetically Encoded FRET Sensor for Cytosolic and Intraorganelle Zn
2+
Imaging
ACS Chemical Biology
2015
82
13
Optical Control of Insulin Secretion Using an Incretin Switch
Angewandte Chemie - International Edition
2015
80
14
mTORC1-to-AMPK switching underlies β cell metabolic plasticity during maturation and diabetes
Journal of Clinical Investigation
2019
80
15
The effects of kisspeptin on β‐cell function, serum metabolites and appetite in humans
Diabetes, Obesity and Metabolism
2018
74
16
SLC30A9 mutation affecting intracellular zinc homeostasis causes a novel cerebro-renal syndrome
Brain
2017
72
17
Biomimetic electromechanical stimulation to maintain adult myocardial slices in vitro
Nature Communications
2019
68
18
Covid-19 and Diabetes: A Complex Bidirectional Relationship
Frontiers in Endocrinology
2020
67
19
Hyperglycemia-Induced Changes in ZIP7 and ZnT7 Expression Cause Zn2+ Release From the Sarco(endo)plasmic Reticulum and Mediate ER Stress in the Heart
Diabetes
2017
66
20
Persistent or Transient Human β Cell Dysfunction Induced by Metabolic Stress: Specific Signatures and Shared Gene Expression with Type 2 Diabetes
Cell Reports
2020
65
21
Lipid-tuned Zinc Transport Activity of Human ZnT8 Protein Correlates with Risk for Type-2 Diabetes
Journal of Biological Chemistry
2016
64
22
DICER Inactivation Identifies Pancreatic β-Cell “Disallowed” Genes Targeted by MicroRNAs
Molecular Endocrinology
2015
63
23
Metabolic and functional specialisations of the pancreatic beta cell: gene disallowance, mitochondrial metabolism and intercellular connectivity
Diabetologia
2020
63
24
Intracellular zinc in insulin secretion and action: a determinant of diabetes risk?
Proceedings of the Nutrition Society
2016
61
25
Adrenaline Stimulates Glucagon Secretion by Tpc2-Dependent Ca2+ Mobilization From Acidic Stores in Pancreatic α-Cells
Diabetes
2018
61
26
Agonist-induced membrane nanodomain clustering drives GLP-1 receptor responses in pancreatic beta cells
PLoS Biology
2019
61
27
Decreased STARD10 Expression Is Associated with Defective Insulin Secretion in Humans and Mice
American Journal of Human Genetics
2017
60
28
Analysis of Purified Pancreatic Islet Beta and Alpha Cell Transcriptomes Reveals 11β-Hydroxysteroid Dehydrogenase (Hsd11b1) as a Novel Disallowed Gene
Frontiers in Genetics
2017
60
29
Dual‐Modal Magnetic Resonance/Fluorescent Zinc Probes for Pancreatic β‐Cell Mass Imaging
Chemistry - A European Journal
2015
57
30
Glucocorticoid Metabolism in Obesity and Following Weight Loss
Frontiers in Endocrinology
2020
56
31
Cancer immunotherapy: Challenges and limitations
Pathology Research and Practice
2022
53
32
Glucocorticoids Reprogram β-Cell Signaling to Preserve Insulin Secretion
Diabetes
2018
52
33
PDX1LOW MAFALOW β-cells contribute to islet function and insulin release
Nature Communications
2021
51
34
A red-shifted photochromic sulfonylurea for the remote control of pancreatic beta cell function
Chemical Communications
2015
49
35
Local and regional control of calcium dynamics in the pancreatic islet
Diabetes, Obesity and Metabolism
2017
49
36
Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) and Endolysosomal Two-pore Channels Modulate Membrane Excitability and Stimulus-Secretion Coupling in Mouse Pancreatic β Cells
Journal of Biological Chemistry
2015
48
37
The transcription factor Pax6 is required for pancreatic β cell identity, glucose-regulated ATP synthesis, and Ca2+ dynamics in adult mice
Journal of Biological Chemistry
2017
48
38
Neuronatin regulates pancreatic β cell insulin content and secretion
Journal of Clinical Investigation
2018
47
39
Allosteric Optical Control of a Class B G‐Protein‐Coupled Receptor
Angewandte Chemie - International Edition
2016
45
40
Mice harboring the human
SLC30A8
R138X loss-of-function mutation have increased insulin secretory capacity
Proceedings of the National Academy of Sciences of the United States of America
2018
45
41
Role of microRNAs in the age-associated decline of pancreatic beta cell function in rat islets
Diabetologia
2016
44
42
Replication and cross-validation of type 2 diabetes subtypes based on clinical variables: an IMI-RHAPSODY study
Diabetologia
2021
44
43
Mechanisms of Weight Loss After Obesity Surgery
Endocrine Reviews
2022
43
44
Molecular phenotyping of multiple mouse strains under metabolic challenge uncovers a role for Elovl2 in glucose-induced insulin secretion
Molecular Metabolism
2017
42
45
Genetic and biased agonist-mediated reductions in β-arrestin recruitment prolong cAMP signaling at glucagon family receptors
Journal of Biological Chemistry
2021
41
46
The Zinc Transporter Slc30a8/ZnT8 Is Required in a Subpopulation of Pancreatic α-Cells for Hypoglycemia-induced Glucagon Secretion
Journal of Biological Chemistry
2015
40
47
Limited impact on glucose homeostasis of leptin receptor deletion from insulin- or proglucagon-expressing cells
Molecular Metabolism
2015
40
48
New Insights into Beta-Cell GLP-1 Receptor and cAMP Signaling
Journal of Molecular Biology
2020
40
49
MiR‐184 expression is regulated by AMPK in pancreatic islets
FASEB Journal
2018
39
50
The pore-forming subunit MCU of the mitochondrial Ca2+ uniporter is required for normal glucose-stimulated insulin secretion in vitro and in vivo in mice
Diabetologia
2020
37
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