| Somatic mutations affect key pathways in lung adenocarcinoma | Nature | 2008 | 2.3K |
| Next-generation DNA sequencing methods | Annual Review of Genomics and Human Genetics | 2008 | 1.5K |
| Effects of the gut microbiota on host adiposity are modulated by the short-chain fatty-acid binding G protein-coupled receptor, Gpr41 | Proceedings of the National Academy of Sciences of the United States of America | 2008 | 1.1K |
| A genome-wide association study of psoriasis and psoriatic arthritis identifies new disease loci | PLoS Genetics | 2008 | 503 |
| TDP-43 A315T mutation in familial motor neuron disease | Annals of Neurology | 2008 | 497 |
| Recurrent reciprocal 1q21.1 deletions and duplications associated with microcephaly or macrocephaly and developmental and behavioral abnormalities | Nature Genetics | 2008 | 457 |
| Whole-genome sequencing and variant discovery in C. elegans | Nature Methods | 2008 | 344 |
| A sequence motif within chromatin entry sites directs MSL establishment on the Drosophila X chromosome | Cell | 2008 | 204 |
| Association of cohesin and Nipped-B with transcriptionally active regions of the Drosophila melanogaster genome | Chromosoma | 2008 | 180 |
| Variants in the CD36 gene associate with the metabolic syndrome and high-density lipoprotein cholesterol | Human Molecular Genetics | 2008 | 144 |
| Revised nomenclature for transposable genetic elements | Plasmid | 2008 | 143 |
| Sociology. The gender gap in NIH grant applications | Science | 2008 | 139 |
| Mechanisms and treatment of cardiovascular disease in Williams-Beuren syndrome | Journal of Clinical Investigation | 2008 | 127 |
| Methods for handling multiple testing | Advances in Genetics | 2008 | 125 |
| Genetic contributions to preterm birth: implications from epidemiological and genetic association studies | Annals of Medicine | 2008 | 115 |
| Evaluating the role of natural selection in the evolution of gene regulation | Heredity | 2008 | 112 |
| Leukocyte tyrosine kinase functions in pigment cell development | PLoS Genetics | 2008 | 105 |
| Asymmetric lower-limb malformations in individuals with homeobox PITX1 gene mutation | American Journal of Human Genetics | 2008 | 101 |
| Temperament and character inventory dimensions and anhedonia in detoxified substance-dependent subjects | American Journal of Drug and Alcohol Abuse | 2008 | 94 |
| Variations in the transcriptome of Alzheimer's disease reveal molecular networks involved in cardiovascular diseases | Genome Biology | 2008 | 78 |
| Lentiviral-transduced human mesenchymal stem cells persistently express therapeutic levels of enzyme in a xenotransplantation model of human disease | Stem Cells | 2008 | 78 |
| Identification of somatic JAK1 mutations in patients with acute myeloid leukemia | Blood | 2008 | 75 |
| Overcoming H-NS-mediated transcriptional silencing of horizontally acquired genes by the PhoP and SlyA proteins in Salmonella enterica | Journal of Biological Chemistry | 2008 | 74 |
| A pathogenic dyskerin mutation impairs proliferation and activates a DNA damage response independent of telomere length in mice | Proceedings of the National Academy of Sciences of the United States of America | 2008 | 73 |
| SORL1 variants and risk of late-onset Alzheimer's disease | Neurobiology of Disease | 2008 | 72 |
