| # | Title | Journal | Year | Citations |
|---|
| 1 | A Rating Scale for Mania: Reliability, Validity and Sensitivity | British Journal of Psychiatry | 1978 | 7,207 |
| 2 | A core gut microbiome in obese and lean twins | Nature | 2009 | 6,819 |
| 3 | Human gut microbiome viewed across age and geography | Nature | 2012 | 6,247 |
| 4 | A New Clinical Scale for the Staging of Dementia | British Journal of Psychiatry | 1982 | 6,182 |
| 5 | A Psychobiological Model of Temperament and Character | Archives of General Psychiatry | 1993 | 4,451 |
| 6 | Genetic studies of body mass index yield new insights for obesity biology | Nature | 2015 | 3,823 |
| 7 | Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease | Nature Genetics | 2013 | 3,741 |
| 8 | The Prevalence of Comorbid Depression in Adults With Diabetes: A meta-analysis | Diabetes Care | 2001 | 3,328 |
| 9 | Gut Microbiota from Twins Discordant for Obesity Modulate Metabolism in Mice | Science | 2013 | 3,006 |
| 10 | Subgenual prefrontal cortex abnormalities in mood disorders | Nature | 1997 | 2,502 |
| 11 | Glutamate and the pathophysiology of hypoxic-ischemic brain damage | Annals of Neurology | 1986 | 2,369 |
| 12 | Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing | Nature Genetics | 2019 | 1,962 |
| 13 | Prediction of Individual Brain Maturity Using fMRI | Science | 2010 | 1,884 |
| 14 | Defining the role of common variation in the genomic and biological architecture of adult human height | Nature Genetics | 2014 | 1,818 |
| 15 | Physical illness in patients with severe mental disorders. I. Prevalence, impact of medications and disparities in health care | World Psychiatry | 2011 | 1,767 |
| 16 | Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease | Nature Genetics | 2011 | 1,708 |
| 17 | Hippocampal atrophy in recurrent major depression. | Proceedings of the National Academy of Sciences of the United States of America | 1996 | 1,698 |
| 18 | The Long-Term Stability of the Human Gut Microbiota | Science | 2013 | 1,696 |
| 19 | Brain Lesions, Obesity, and Other Disturbances in Mice Treated with Monosodium Glutamate | Science | 1969 | 1,653 |
| 20 | A new, semi-structured psychiatric interview for use in genetic linkage studies: a report on the reliability of the SSAGA. | Journal of Studies on Alcohol and Drugs | 1994 | 1,614 |
| 21 | Glutamate Receptor Dysfunction and Schizophrenia | Archives of General Psychiatry | 1995 | 1,569 |
| 22 | Depression and poor glycemic control: a meta-analytic review of the literature | Diabetes Care | 2000 | 1,501 |
| 23 | Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use | Nature Genetics | 2019 | 1,307 |
| 24 | Ethanol-Induced Apoptotic Neurodegeneration and Fetal Alcohol Syndrome | Science | 2000 | 1,293 |
| 25 | Function in the human connectome: Task-fMRI and individual differences in behavior | NeuroImage | 2013 | 1,259 |
| 26 | Validation of a brief quantitative measure of autistic traits: comparison of the social responsiveness scale with the autism diagnostic interview-revised | Journal of Autism and Developmental Disorders | 2003 | 1,238 |
| 27 | Depression Duration But Not Age Predicts Hippocampal Volume Loss in Medically Healthy Women with Recurrent Major Depression | Journal of Neuroscience | 1999 | 1,211 |
| 28 | Pathological changes induced in cerebrocortical neurons by phencyclidine and related drugs | Science | 1989 | 1,207 |
| 29 | Genome-wide association study identifies 74 loci associated with educational attainment | Nature | 2016 | 1,204 |
| 30 | A functional anatomical study of unipolar depression | Journal of Neuroscience | 1992 | 1,178 |
| 31 | Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes | Nature Genetics | 2018 | 1,124 |
| 32 | Post-Traumatic Stress Disorder in the General Population | New England Journal of Medicine | 1987 | 1,072 |
| 33 | Viruses in the faecal microbiota of monozygotic twins and their mothers | Nature | 2010 | 1,054 |
| 34 | Autistic Traits in the General Population | Archives of General Psychiatry | 2003 | 1,045 |
| 35 | Resting-state functional MRI in depression unmasks increased connectivity between networks via the dorsal nexus | Proceedings of the National Academy of Sciences of the United States of America | 2010 | 1,032 |
| 36 | Trends in Opioid Analgesic Abuse and Mortality in the United States | New England Journal of Medicine | 2015 | 1,002 |
| 37 | The co-occurrence of alcoholism with other psychiatric disorders in the general population and its impact on treatment. | Journal of Studies on Alcohol and Drugs | 1988 | 961 |
| 38 | Sturdy childhood predictors of adult antisocial behaviour: replications from longitudinal studies | Psychological Medicine | 1978 | 945 |
| 39 | The Tridimensional Personality Questionnaire: U.S. Normative Data | Psychological Reports | 1991 | 933 |
| 40 | Second-Generation (Atypical) Antipsychotics and Metabolic Effects | CNS Drugs | 2005 | 921 |
| 41 | NMDA receptor hypofunction model of schizophrenia | Journal of Psychiatric Research | 1999 | 884 |
| 42 | Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses | Nature Genetics | 2016 | 870 |
| 43 | ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy | Nature | 2017 | 852 |
| 44 | Reproducible brain-wide association studies require thousands of individuals | Nature | 2022 | 842 |
| 45 | The Human Connectome Project's neuroimaging approach | Nature Neuroscience | 2016 | 825 |
| 46 | NMDA antagonist neurotoxicity: mechanism and prevention | Science | 1991 | 821 |
| 47 | Genome-wide association study identifies a second prostate cancer susceptibility variant at 8q24 | Nature Genetics | 2007 | 818 |
| 48 | PGC-1α Deficiency Causes Multi-System Energy Metabolic Derangements: Muscle Dysfunction, Abnormal Weight Control and Hepatic Steatosis | PLoS Biology | 2005 | 817 |
| 49 | Cannabis use and mental health in young people: cohort study | BMJ: British Medical Journal | 2002 | 809 |
| 50 | Identification of seven loci affecting mean telomere length and their association with disease | Nature Genetics | 2013 | 808 |
