| # | Title | Journal | Year | Citations |
|---|
| 1 | Cancer Immunoediting: Integrating Immunity’s Roles in Cancer Suppression and Promotion | Science | 2011 | 4,987 |
| 2 | Cancer immunoediting: from immunosurveillance to tumor escape | Nature Immunology | 2002 | 4,290 |
| 3 | Interleukin 17–producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages | Nature Immunology | 2005 | 4,106 |
| 4 | Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 | Cell Death and Differentiation | 2018 | 4,036 |
| 5 | Neoantigens in cancer immunotherapy | Science | 2015 | 3,809 |
| 6 | A Unique Microglia Type Associated with Restricting Development of Alzheimer’s Disease | Cell | 2017 | 3,282 |
| 7 | Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9 | Nature Biotechnology | 2016 | 3,168 |
| 8 | Guidelines for the use and interpretation of assays for monitoring autophagy | Autophagy | 2012 | 3,122 |
| 9 | The Immunobiology of Cancer Immunosurveillance and Immunoediting | Immunity | 2004 | 2,486 |
| 10 | The Three Es of Cancer Immunoediting | Annual Review of Immunology | 2004 | 2,422 |
| 11 | IFNγ and lymphocytes prevent primary tumour development and shape tumour immunogenicity | Nature | 2001 | 2,400 |
| 12 | Metabolic Competition in the Tumor Microenvironment Is a Driver of Cancer Progression | Cell | 2015 | 2,158 |
| 13 | Innate lymphoid cells — a proposal for uniform nomenclature | Nature Reviews Immunology | 2013 | 2,054 |
| 14 | National Institute on Aging–Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease | Alzheimer's and Dementia | 2012 | 1,968 |
| 15 | Posttranscriptional Control of T Cell Effector Function by Aerobic Glycolysis | Cell | 2013 | 1,715 |
| 16 | Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens | Nature | 2014 | 1,705 |
| 17 | Natural Innate and Adaptive Immunity to Cancer | Annual Review of Immunology | 2011 | 1,691 |
| 18 | Batf3 Deficiency Reveals a Critical Role for CD8α + Dendritic Cells in Cytotoxic T Cell Immunity | Science | 2008 | 1,665 |
| 19 | No evidence that carotenoid pigments boost either immune or antioxidant defenses in a songbird | Nature Communications | 2018 | 1,639 |
| 20 | The lineage decisions of helper T cells | Nature Reviews Immunology | 2002 | 1,519 |
| 21 | Microglia Function in the Central Nervous System During Health and Neurodegeneration | Annual Review of Immunology | 2017 | 1,450 |
| 22 | Plasmacytoid dendritic cells in immunity | Nature Immunology | 2004 | 1,432 |
| 23 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
| 24 | A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells | Nature | 2008 | 1,341 |
| 25 | The Shared Antibiotic Resistome of Soil Bacteria and Human Pathogens | Science | 2012 | 1,314 |
| 26 | Interferons, immunity and cancer immunoediting | Nature Reviews Immunology | 2006 | 1,312 |
| 27 | Metabolic Pathways in Immune Cell Activation and Quiescence | Immunity | 2013 | 1,271 |
| 28 | Standards and Guidelines for the Interpretation and Reporting of Sequence Variants in Cancer | Journal of Molecular Diagnostics | 2017 | 1,267 |
| 29 | Mitochondrial DNA stress primes the antiviral innate immune response | Nature | 2015 | 1,255 |
| 30 | TREM2 Lipid Sensing Sustains the Microglial Response in an Alzheimer’s Disease Model | Cell | 2015 | 1,236 |
| 31 | TNF-α induces osteoclastogenesis by direct stimulation of macrophages exposed to permissive levels of RANK ligand | Journal of Clinical Investigation | 2000 | 1,219 |
| 32 | Adaptive immunity maintains occult cancer in an equilibrium state | Nature | 2007 | 1,204 |
| 33 | New insights into cancer immunoediting and its three component phases—elimination, equilibrium and escape | Current Opinion in Immunology | 2014 | 1,163 |
| 34 | Embryonic and Adult-Derived Resident Cardiac Macrophages Are Maintained through Distinct Mechanisms at Steady State and during Inflammation | Immunity | 2014 | 1,120 |
| 35 | A human natural killer cell subset provides an innate source of IL-22 for mucosal immunity | Nature | 2009 | 1,114 |
| 36 | Genome remodelling in a basal-like breast cancer metastasis and xenograft | Nature | 2010 | 1,077 |
| 37 | Cancer exome analysis reveals a T-cell-dependent mechanism of cancer immunoediting | Nature | 2012 | 1,075 |
| 38 | Fueling Immunity: Insights into Metabolism and Lymphocyte Function | Science | 2013 | 1,070 |
| 39 | Distinct Effects of T-bet in TH1 Lineage Commitment and IFN-gamma Production in CD4 and CD8 T Cells | Science | 2002 | 1,064 |
| 40 | Primary age-related tauopathy (PART): a common pathology associated with human aging | Acta Neuropathologica | 2014 | 1,060 |
| 41 | Positive and negative selection of the T cell repertoire: what thymocytes see (and don't see) | Nature Reviews Immunology | 2014 | 1,043 |
| 42 | Disease-Specific Alterations in the Enteric Virome in Inflammatory Bowel Disease | Cell | 2015 | 1,036 |
| 43 | Mitochondrial Dynamics Controls T Cell Fate through Metabolic Programming | Cell | 2016 | 1,025 |
| 44 | Dendritic cell regulation of TH1-TH2 development | Nature Immunology | 2000 | 1,017 |
| 45 | Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3 | Nature | 2006 | 1,016 |
| 46 | Essential role of mda-5 in type I IFN responses to polyriboinosinic:polyribocytidylic acid and encephalomyocarditis picornavirus | Proceedings of the National Academy of Sciences of the United States of America | 2006 | 1,013 |
| 47 | Cytokine Signaling in 2002 | Cell | 2002 | 978 |
| 48 | Selection of evolutionarily conserved mucosal-associated invariant T cells by MR1 | Nature | 2003 | 978 |
| 49 | Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis | Nature | 2012 | 975 |
| 50 | Bacterial phylogeny structures soil resistomes across habitats | Nature | 2014 | 973 |
