Centre for Integrative Systems Biology and Bioinformatics

104(top 1%)

papers

5.8K(top 1%)

citations

36(top 1%)

h-index

76(top 1%)

g-index

130

all documents

7.2K

doc citations

1.4K

citing journals

Top Articles

#	Title	Journal	Year	Citations
1	Creation and analysis of biochemical constraint-based models using the COBRA Toolbox v.3.0	Nature Protocols	2019	833
2	A Highly Conserved Program of Neuronal Microexons Is Misregulated in Autistic Brains	Cell	2014	546
3	Critical Truths About Power Laws	Science	2012	501
4	Gene Regulatory Network Inference from Single-Cell Data Using Multivariate Information Measures	Cell Systems	2017	414
5	Can Predicted Protein 3D Structures Provide Reliable Insights into whether Missense Variants Are Disease Associated?	Journal of Molecular Biology	2019	344
6	A large fraction of HLA class I ligands are proteasome-generated spliced peptides	Science	2016	322
7	An expanded evaluation of protein function prediction methods shows an improvement in accuracy	Genome Biology	2016	308
8	SuSPect: Enhanced Prediction of Single Amino Acid Variant (SAV) Phenotype Using Network Features	Journal of Molecular Biology	2014	189
9	A framework for parameter estimation and model selection from experimental data in systems biology using approximate Bayesian computation	Nature Protocols	2014	185
10	The Effects of Non-Synonymous Single Nucleotide Polymorphisms (nsSNPs) on Protein–Protein Interactions	Journal of Molecular Biology	2013	184
11	Stem Cell Differentiation as a Non-Markov Stochastic Process	Cell Systems	2017	178
12	Protein-protein interaction sites are hot spots for disease-associated nonsynonymous SNPs	Human Mutation	2012	149
13	EzMol: A Web Server Wizard for the Rapid Visualization and Image Production of Protein and Nucleic Acid Structures	Journal of Molecular Biology	2018	145
14	Maximizing the Information Content of Experiments in Systems Biology	PLoS Computational Biology	2013	142
15	Protein–Protein Interactions in Virus–Host Systems	Frontiers in Microbiology	2017	113
16	IGSF 10 mutations dysregulate gonadotropin‐releasing hormone neuronal migration resulting in delayed puberty	EMBO Molecular Medicine	2016	109
17	Proteasome isoforms exhibit only quantitative differences in cleavage and epitope generation	European Journal of Immunology	2014	107
18	The Contribution of Missense Mutations in Core and Rim Residues of Protein–Protein Interfaces to Human Disease	Journal of Molecular Biology	2015	105
19	Model selection in systems and synthetic biology	Current Opinion in Biotechnology	2013	100
20	Single-cell transcriptomics reveals multi-step adaptations to endocrine therapy	Nature Communications	2019	93
21	Structure-based prediction of protein allostery	Current Opinion in Structural Biology	2018	90
22	AlloPred: prediction of allosteric pockets on proteins using normal mode perturbation analysis	BMC Bioinformatics	2015	88
23	Topological sensitivity analysis for systems biology	Proceedings of the National Academy of Sciences of the United States of America	2014	80
24	Systems biology (un)certainties	Science	2015	77
25	Quantification of HTLV-1 Clonality and TCR Diversity	PLoS Computational Biology	2014	71
26	Genome wide analysis of the complete GlnR nitrogen-response regulon in Mycobacterium smegmatis	BMC Genomics	2013	66
27	Multivariate moment closure techniques for stochastic kinetic models	Journal of Chemical Physics	2015	66
28	Robustness of MEK-ERK Dynamics and Origins of Cell-to-Cell Variability in MAPK Signaling	Cell Reports	2016	57
29	Persistent and polarized global actin flow is essential for directionality during cell migration	Nature Cell Biology	2019	57
30	Information theory and signal transduction systems: From molecular information processing to network inference	Seminars in Cell and Developmental Biology	2014	51
31	k-SLAM: accurate and ultra-fast taxonomic classification and gene identification for large metagenomic data sets	Nucleic Acids Research	2017	50
32	Deciphering the metabolic response of Mycobacterium tuberculosis to nitrogen stress	Molecular Microbiology	2015	49
33	Multi-level Strategy for Identifying Proteasome-Catalyzed Spliced Epitopes Targeted by CD8+ T Cells during Bacterial Infection	Cell Reports	2017	46
34	Considerate approaches to constructing summary statistics for ABC model selection	Statistics and Computing	2012	45
35	Predicting Protein Dynamics and Allostery Using Multi-Protein Atomic Distance Constraints	Structure	2017	45
36	Transition state characteristics during cell differentiation	PLoS Computational Biology	2018	45
37	Single-cell analyses and machine learning define hematopoietic progenitor and HSC-like cells derived from human PSCs	Blood	2020	44
38	The South Asian Genome	PLoS ONE	2014	43
39	In Silico Analysis of the Small Molecule Content of Outer Membrane Vesicles Produced by Bacteroides thetaiotaomicron Indicates an Extensive Metabolic Link between Microbe and Host	Frontiers in Microbiology	2017	42
40	Chromosome Translocation Inflates Bacillus Forespores and Impacts Cellular Morphology	Cell	2018	42
41	CD8⁺ T cells of Listeria monocytogenes‐infected mice recognize both linear and spliced proteasome products	European Journal of Immunology	2016	39
42	Quantitative time-resolved analysis reveals intricate, differential regulation of standard- and immuno-proteasomes	ELife	2015	39
43	An in silico—in vitro Pipeline Identifying an HLA-A*02:01+ KRAS G12V+ Spliced Epitope Candidate for a Broad Tumor-Immune Response in Cancer Patients	Frontiers in Immunology	2019	38
44	Extracellular proteasome-osteopontin circuit regulates cell migration with implications in multiple sclerosis	Scientific Reports	2017	35
45	Learning regulatory models for cell development from single cell transcriptomic data	Current Opinion in Systems Biology	2017	33
46	Proteins and Domains Vary in Their Tolerance of Non-Synonymous Single Nucleotide Polymorphisms (nsSNPs)	Journal of Molecular Biology	2013	32
47	Calibrating spatio-temporal models of leukocyte dynamics against in vivo live-imaging data using approximate Bayesian computation	Integrative Biology (United Kingdom)	2012	31
48	Contributions of Function-Altering Variants in Genes Implicated in Pubertal Timing and Body Mass for Self-Limited Delayed Puberty	Journal of Clinical Endocrinology and Metabolism	2018	31
49	Bayesian design strategies for synthetic biology	Interface Focus	2011	29
50	EAP1 regulation of GnRH promoter activity is important for human pubertal timing	Human Molecular Genetics	2019	29

Profile

Scientometrics

Citing Bodies

Centre for Integrative Systems Biology and Bioinformatics

Top Articles