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Top Articles

#TitleJournalYearCitations
1The emerging roles of forkhead box (Fox) proteins in cancerNature Reviews Cancer2007939
2Definition of microRNAs That Repress Expression of the Tumor Suppressor Gene FOXO1 in Endometrial CancerCancer Research2010308
3Thiostrepton selectively targets breast cancer cells through inhibition of forkhead box M1 expressionMolecular Cancer Therapeutics2008206
4FOXO transcription factors: key regulators of cell fateBiochemical Society Transactions2006198
5Transcriptional Cross Talk between the Forkhead Transcription Factor Forkhead Box O1A and the Progesterone Receptor Coordinates Cell Cycle Regulation and Differentiation in Human Endometrial Stromal CellsMolecular Endocrinology2007189
6FOXM1 Confers Acquired Cisplatin Resistance in Breast Cancer CellsMolecular Cancer Research2010172
7Many forks in the path: cycling with FoxOOncogene2008165
8A novel and validated prognostic index in hepatocellular carcinoma: The inflammation based index (IBI)Journal of Hepatology2012164
9Differential Expression of FOXO1 and FOXO3a Confers Resistance to Oxidative Cell Death upon Endometrial DecidualizationMolecular Endocrinology2006162
10Brief Communication: Rituximab in HIV-Associated Multicentric Castleman DiseaseAnnals of Internal Medicine2007162
11Induction of Mxi1-SRα by FOXO3a Contributes to Repression of Myc-Dependent Gene ExpressionMolecular and Cellular Biology2007158
12Positron emission tomography imaging of drug-induced tumor apoptosis with a caspase-3/7 specific [ 18 F]-labeled isatin sulfonamideProceedings of the National Academy of Sciences of the United States of America2009157
13The Forkhead Box M1 Protein Regulates the Transcription of the Estrogen Receptor α in Breast Cancer CellsJournal of Biological Chemistry2006152
14The Forkhead Transcription Factor FOXO3a Increases Phosphoinositide-3 Kinase/Akt Activity in Drug-Resistant Leukemic Cells through Induction of PIK3CA ExpressionMolecular and Cellular Biology2008150
15The Role of Androgen Receptor Mutations in Prostate Cancer ProgressionCurrent Genomics2009147
16The Androgen and Progesterone Receptors Regulate Distinct Gene Networks and Cellular Functions in Decidualizing EndometriumEndocrinology2008140
17Identification of 13 novel NLRP7 mutations in 20 families with recurrent hydatidiform mole; missense mutations cluster in the leucine-rich regionJournal of Medical Genetics2009138
18Wnt-11 promotes neuroendocrine-like differentiation, survival and migration of prostate cancer cellsMolecular Cancer2010135
19Expression of FOXA1 and GATA-3 in breast cancer: the prognostic significance in hormone receptor-negative tumoursBreast Cancer Research2009134
20Estrogen Receptor β2 Negatively Regulates the Transactivation of Estrogen Receptor α in Human Breast Cancer CellsCancer Research2007133
21A Small-Molecule Inhibitor for Phosphatase and Tensin Homologue Deleted on Chromosome 10 (PTEN)ACS Chemical Biology2006131
22Mechanism and functional consequences of loss of FOXO1 expression in endometrioid endometrial cancer cellsOncogene2008130
23Application of ProTide Technology to Gemcitabine: A Successful Approach to Overcome the Key Cancer Resistance Mechanisms Leads to a New Agent (NUC-1031) in Clinical DevelopmentJournal of Medicinal Chemistry2014125
24CpG island methylator phenotype (CIMP) in cancer: Causes and implicationsCancer Letters2008120
25Mechano-transduction in Osteoblastic Cells Involves Strain-regulated Estrogen Receptor α-mediated Control of Insulin-like Growth Factor (IGF) I Receptor Sensitivity to Ambient IGF, Leading to Phosphatidylinositol 3-Kinase/AKT-dependent Wnt/LRP5 Receptor-independent Activation of β-Catenin SignalingJournal of Biological Chemistry2010119
26Gefitinib (Iressa) represses FOXM1 expression via FOXO3a in breast cancerMolecular Cancer Therapeutics2009115
27Regulation of prostate cell growth and morphogenesis by Dickkopf-3Oncogene2006113
28Phosphorylation at serines 104 and 106 by Erk1/2 MAPK is important for estrogen receptor-α activityJournal of Molecular Endocrinology2008108
29Regulation of the SUMO pathway sensitizes differentiating human endometrial stromal cells to progesteroneProceedings of the National Academy of Sciences of the United States of America2006102
30The DEAD-box protein p72 regulates ERα-/oestrogen-dependent transcription and cell growth, and is associated with improved survival in ERα-positive breast cancerOncogene2009102
31CD3 limits the efficacy of TCR gene therapy in vivoBlood2011101
32The DEAD box RNA helicases p68 (Ddx5) and p72 (Ddx17): novel transcriptional co-regulatorsBiochemical Society Transactions200893
33Phosphorylation of ERα at serine 118 in primary breast cancer and in tamoxifen-resistant tumours is indicative of a complex role for ERα phosphorylation in breast cancer progressionEndocrine-Related Cancer200691
34WWOX Gene Expression Abolishes Ovarian Cancer Tumorigenicity In vivo and Decreases Attachment to Fibronectin via Integrin α3Cancer Research200991
35FoxM1c Counteracts Oxidative Stress-induced Senescence and Stimulates Bmi-1 ExpressionJournal of Biological Chemistry200887
36Resist or die: FOXO transcription factors determine the cellular response to chemotherapyCell Cycle200881
37Absence of Maternal Methylation in Biparental Hydatidiform Moles from Women with NLRP7 Maternal-Effect Mutations Reveals Widespread Placenta-Specific ImprintingPLoS Genetics201580
38Phosphorylation of Estrogen Receptor-α at Ser167 Is Indicative of Longer Disease-Free and Overall Survival in Breast Cancer PatientsClinical Cancer Research200779
39Inhibition of γ-secretase induces G2/M arrest and triggers apoptosis in breast cancer cellsBritish Journal of Cancer200979
40Comparison of bone marrow, disseminated tumour cells and blood-circulating tumour cells in breast cancer patients after primary treatmentBritish Journal of Cancer200978
41The transcription factor FOXO3a is a crucial cellular target of gefitinib (Iressa) in breast cancer cellsMolecular Cancer Therapeutics200777
42FoxM1 is a downstream target and marker of HER2 overexpression in breast cancerInternational Journal of Oncology200977
43Monitoring Predominantly Cytostatic Treatment Response with 18F-FDG PETJournal of Nuclear Medicine200975
44Prohibitin, a protein downregulated by androgens, represses androgen receptor activityOncogene200774
45Detection of HER2 amplification in circulating free DNA in patients with breast cancerBritish Journal of Cancer201174
46Mechanisms of androgen receptor activation in advanced prostate cancer: differential co-activator recruitment and gene expressionOncogene200873
47Nicastrin regulates breast cancer stem cell properties and tumor growth in vitro and in vivoProceedings of the National Academy of Sciences of the United States of America201271
48The liver receptor homolog-1 regulates estrogen receptor expression in breast cancer cellsBreast Cancer Research and Treatment201170
49The clinical significance of disseminated tumor cells in breast cancerNature Clinical Practice Oncology200768
50Measurements of EGFR expression on circulating tumor cells are reproducible over time in metastatic breast cancer patientsPharmacogenomics200967