| # | Title | Journal | Year | Citations |
|---|
| 1 | Effect of long-acting nifedipine on mortality and cardiovascular morbidity in patients with stable angina requiring treatment (ACTION trial): randomised controlled trial | Lancet, The | 2004 | 468 |
| 2 | Gap junction alterations in human cardiac disease | Cardiovascular Research | 2004 | 265 |
| 3 | Oscillatory Breathing Patterns During Wakefulness in Patients With Chronic Heart Failure | Circulation | 1999 | 196 |
| 4 | Cyclic ADP-ribose, the ryanodine receptor and Ca2+ release | Trends in Pharmacological Sciences | 1995 | 152 |
| 5 | Critical role of toll-like receptors and nucleotide oligomerisation domain in the regulation of health and disease | Journal of Endocrinology | 2007 | 118 |
| 6 | Spatiotemporal pattern of commitment to slowed proliferation in the embryonic mouse heart indicates progressive differentiation of the cardiac conduction system | The Anatomical Record | 2003 | 109 |
| 7 | Effects of Oral Testosterone Treatment on Myocardial Perfusion and Vascular Function in Men With Low Plasma Testosterone and Coronary Heart Disease | American Journal of Cardiology | 2008 | 97 |
| 8 | A randomized trial of carvedilol after renin-angiotensin system inhibition in chronic Chagas cardiomyopathy | American Heart Journal | 2007 | 91 |
| 9 | Rationale and design of the carvedilol or metoprolol European trial in patients with chronic heart failure: COMET | European Journal of Heart Failure | 2002 | 69 |
| 10 | Comparison of connexin expression patterns in the developing mouse heart and human foetal heart | Molecular and Cellular Biochemistry | 2003 | 69 |
| 11 | Myofilament dysfunction in cardiac disease from mice to men | Journal of Muscle Research and Cell Motility | 2008 | 67 |
| 12 | Incidence and outcome of persons with a clinical diagnosis of heart failure in a general practice population of 696,884 in the United Kingdom | European Journal of Heart Failure | 2005 | 63 |
| 13 | Recent developments: Management of chronic heart failure | BMJ: British Medical Journal | 2002 | 60 |
| 14 | Adherence and perception of medication in patients with chronic heart failure during a five-year randomised trial | Patient Education and Counseling | 2006 | 60 |
| 15 | A Model of the Putative Pore Region of the Cardiac Ryanodine Receptor Channel | Biophysical Journal | 2004 | 56 |
| 16 | Activation of PPARβ/δ inhibits leukocyte recruitment, cell adhesion molecule expression, and chemokine release | Journal of Leukocyte Biology | 2009 | 56 |
| 17 | Electrophysiological effects of ryanodine derivatives on the sheep cardiac sarcoplasmic reticulum calcium-release channel | Biophysical Journal | 1996 | 54 |
| 18 | Bone mineral status and bone loss over time in men with chronic systolic heart failure and their clinical and hormonal determinants | European Journal of Heart Failure | 2009 | 54 |
| 19 | COX‐1, and not COX‐2 activity, regulates airway function: relevance to aspirin‐sensitive asthma | FASEB Journal | 2008 | 53 |
| 20 | The red wine polyphenol, resveratrol, exerts acute direct actions on guinea-pig ventricular myocytes | European Journal of Pharmacology | 2005 | 48 |
| 21 | Genomic deletion of estrogen receptors ERα and ERβ does not alter estrogen-mediated inhibition of Ca2+influx and contraction in murine cardiomyocytes | American Journal of Physiology - Heart and Circulatory Physiology | 2008 | 44 |
| 22 | The molecular phenotype of human cardiac myosin associated with hypertrophic obstructive cardiomyopathy | Cardiovascular Research | 2008 | 41 |
| 23 | Randomized trial of effects of continuous combined HRT on markers of lipids and coagulation in women with acute coronary syndromes: WHISP Pilot Study | European Heart Journal | 2006 | 35 |
| 24 | Oestrogen directly inhibits the cardiovascular L-type Ca2+ channel Cav1.2 | Biochemical and Biophysical Research Communications | 2007 | 35 |
| 25 | Effects of radial artery harvesting on forearm function and blood flow | Annals of Thoracic Surgery | 2003 | 31 |
| 26 | Deficiencies in circulating testosterone and dehydroepiandrosterone sulphate, and depression in men with systolic chronic heart failure | European Journal of Heart Failure | 2010 | 31 |
| 27 | Comparison of connexin expression patterns in the developing mouse heart and human foetal heart | Molecular and Cellular Biochemistry | 2003 | 30 |
| 28 | The functions of two species of calcium channel in cardiac muscle excitation-contraction coupling | European Heart Journal | 1997 | 28 |
| 29 | Incidence and outcome of atrial fibrillation in stable symptomatic coronary disease | Scandinavian Cardiovascular Journal | 2006 | 28 |
| 30 | Evidence against the regulation of caldesmon inhibitory activity by p42/p44erkmitogen-activated protein kinase in vitro and demonstration of another caldesmon kinase in intact gizzard smooth muscle | FEBS Letters | 1999 | 26 |
| 31 | Overexpression of β 1 -adrenoceptors in adult rat ventricular myocytes enhances CGP 12177A cardiostimulation: implications for ‘putative’β 4 -adrenoceptor pharmacology | British Journal of Pharmacology | 2004 | 26 |
| 32 | Comparison of flow characteristics and vascular reactivity of radial artery and long saphenous vein grafts [NCT00139399] | Journal of Cardiothoracic Surgery | 2006 | 25 |
| 33 | Cardiac action potential duration and calcium regulation in males and females | Biochemical and Biophysical Research Communications | 2009 | 24 |
| 34 | Diagnostic criteria and adjudication process both determine published event-rates: The ACTION trial experience | Contemporary Clinical Trials | 2007 | 23 |
| 35 | Comparison of Connexin 43, 40 and 45 Expression Patterns in the Developing Human and Mouse Hearts | Cell Communication and Adhesion | 2001 | 22 |
| 36 | Uric acid and other renal function parameters in patients with stable angina pectoris participating in the ACTION trial: impact of nifedipine GITS (gastro-intestinal therapeutic system) and relation to outcome | Journal of Hypertension | 2007 | 21 |
| 37 | Soy-Derived Isoflavones Exert Opposing Actions on Guinea Pig Ventricular Myocytes | Journal of Pharmacology and Experimental Therapeutics | 2003 | 20 |
| 38 | Gender determines the acute actions of genistein on intracellular calcium regulation in the guinea-pig heart | Cardiovascular Research | 2004 | 19 |
| 39 | Raloxifene acutely suppresses ventricular myocyte contractility through inhibition of the L-type calcium current | British Journal of Pharmacology | 2004 | 19 |
| 40 | Pharmacological Regulators of Intracellular Calcium Release Channels | Current Pharmaceutical Design | 2007 | 19 |
| 41 | Role of Caldesmon in the Ca2+ Regulation of Smooth Muscle Thin Filaments | Journal of Biological Chemistry | 2008 | 18 |
| 42 | Electrostatic Mechanisms Underlie Neomycin Block of the Cardiac Ryanodine Receptor Channel (RyR2) | Biophysical Journal | 2004 | 17 |
| 43 | Changes in Negative Charge at the Luminal Mouth of the Pore Alter Ion Handling and Gating in the Cardiac Ryanodine-Receptor | Biophysical Journal | 2009 | 16 |
| 44 | The effects of overexpression of the Na+/Ca2+ exchanger on calcium regulation in hypertrophied mouse cardiac myocytes | Cell Calcium | 2004 | 14 |
| 45 | Clinical course of isolated stable angina due to coronary heart disease | European Heart Journal | 2007 | 13 |
| 46 | Predictive value of local and core laboratory echocardiographic assessment of cardiac function in patients with chronic stable angina: The ACTION study | European Journal of Echocardiography | 2007 | 13 |
| 47 | Gender Differences in Cardiac Remodeling and Clinical Outcomes in Chronic Stable Angina Pectoris (from the ACTION Trial) | American Journal of Cardiology | 2010 | 11 |
| 48 | Cyclic AMP levels in ventricular myocytes from noradrenaline-treated guinea-pigs | European Journal of Pharmacology | 1996 | 8 |
| 49 | A commonly occurring polymorphism upstream of the estrogen receptor alpha alters transcription and is associated with increased HDL | Atherosclerosis | 2008 | 8 |
| 50 | Coronary vasomotor and blood flow responses to isoflavone-intact soya protein in subjects with coronary heart disease or risk factors for coronary heart disease | Clinical Science | 2008 | 8 |
