| # | Title | Journal | Year | Citations |
|---|
| 1 | SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues | Cell | 2020 | 1,956 |
| 2 | Childhood Functional Gastrointestinal Disorders: Child/Adolescent | Gastroenterology | 2006 | 1,432 |
| 3 | SARS-CoV-2 mRNA vaccine design enabled by prototype pathogen preparedness | Nature | 2020 | 1,153 |
| 4 | Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) Is Mediated by the Viral Polymerase and the Proofreading Exoribonuclease | MBio | 2018 | 1,142 |
| 5 | Roadmap to embryo implantation: clues from mouse models | Nature Reviews Genetics | 2006 | 1,070 |
| 6 | Iron in Infection and Immunity | Cell Host and Microbe | 2013 | 1,000 |
| 7 | Molecular Cues to Implantation | Endocrine Reviews | 2004 | 956 |
| 8 | Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen | Proceedings of the National Academy of Sciences of the United States of America | 2017 | 944 |
| 9 | An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 in human airway epithelial cell cultures and multiple coronaviruses in mice | Science Translational Medicine | 2020 | 886 |
| 10 | Human Metapneumovirus and Lower Respiratory Tract Disease in Otherwise Healthy Infants and Children | New England Journal of Medicine | 2004 | 850 |
| 11 | The Underrecognized Burden of Influenza in Young Children | New England Journal of Medicine | 2006 | 819 |
| 12 | Infectious Diseases Society of America Guidelines on the Treatment and Management of Patients With Coronavirus Disease 2019 (COVID-19) | Clinical Infectious Diseases | 2020 | 708 |
| 13 | Nutritional aspects of manganese homeostasis | Molecular Aspects of Medicine | 2005 | 683 |
| 14 | Characteristics and Outcomes of US Children and Adolescents With Multisystem Inflammatory Syndrome in Children (MIS-C) Compared With Severe Acute COVID-19 | JAMA - Journal of the American Medical Association | 2021 | 617 |
| 15 | Single-cell RNA sequencing reveals profibrotic roles of distinct epithelial and mesenchymal lineages in pulmonary fibrosis | Science Advances | 2020 | 571 |
| 16 | Mutations in kelch-like 3 and cullin 3 cause hypertension and electrolyte abnormalities | Nature | 2012 | 560 |
| 17 | Drug and Bile Acid Transporters in Rosuvastatin Hepatic Uptake: Function, Expression, and Pharmacogenetics | Gastroenterology | 2006 | 542 |
| 18 | Association Between mRNA Vaccination and COVID-19 Hospitalization and Disease Severity | JAMA - Journal of the American Medical Association | 2021 | 458 |
| 19 | Remdesivir Inhibits SARS-CoV-2 in Human Lung Cells and Chimeric SARS-CoV Expressing the SARS-CoV-2 RNA Polymerase in Mice | Cell Reports | 2020 | 412 |
| 20 | Development and Validation of the Rome IV Diagnostic Questionnaire for Adults | Gastroenterology | 2016 | 400 |
| 21 | Clinical severity of, and effectiveness of mRNA vaccines against, covid-19 from omicron, delta, and alpha SARS-CoV-2 variants in the United States: prospective observational study | BMJ, The | 2022 | 393 |
| 22 | Coronaviruses Lacking Exoribonuclease Activity Are Susceptible to Lethal Mutagenesis: Evidence for Proofreading and Potential Therapeutics | PLoS Pathogens | 2013 | 392 |
| 23 | Safety and Immunogenicity of Heptavalent Pneumococcal Vaccine Conjugated to CRM197in United States Infants | Pediatrics | 1998 | 377 |
| 24 | Bone morphogenetic protein 4 regulates the budding site and elongation of the mouse ureter | Journal of Clinical Investigation | 2000 | 370 |
| 25 | Role of the Angiotensin Type 2 Receptor Gene in Congenital Anomalies of the Kidney and Urinary Tract, CAKUT, of Mice and Men | Molecular Cell | 1999 | 357 |
| 26 | Neutralizing human antibodies prevent Zika virus replication and fetal disease in mice | Nature | 2016 | 349 |
| 27 | Precision Medicine, AI, and the Future of Personalized Health Care | Clinical and Translational Science | 2021 | 349 |
| 28 | Whole Exome Sequencing to Identify a Novel Gene (Caveolin-1) Associated With Human Pulmonary Arterial Hypertension | Circulation: Cardiovascular Genetics | 2012 | 333 |
| 29 | Infection Prevention and Control Guideline for Cystic Fibrosis: 2013 Update | Infection Control and Hospital Epidemiology | 2014 | 322 |
| 30 | Clinical trial of vitamin A supplementation in infants susceptible to bronchopulmonary dysplasia | Journal of Pediatrics | 1987 | 316 |
| 31 | Prostaglandin E2 promotes colorectal adenoma growth via transactivation of the nuclear peroxisome proliferator-activated receptor δ | Cancer Cell | 2004 | 314 |
| 32 | Role of manganese in neurodegenerative diseases | Journal of Trace Elements in Medicine and Biology | 2011 | 311 |
| 33 | Murine double nullizygotes of the angiotensin type 1A and 1B receptor genes duplicate severe abnormal phenotypes of angiotensinogen nullizygotes. | Journal of Clinical Investigation | 1998 | 311 |
| 34 | CXCL1 induced by prostaglandin E2 promotes angiogenesis in colorectal cancer | Journal of Experimental Medicine | 2006 | 303 |
| 35 | The transmembrane activator TACI triggers immunoglobulin class switching by activating B cells through the adaptor MyD88 | Nature Immunology | 2010 | 295 |
| 36 | SyM-BBB: a microfluidic blood brain barrier model | Lab on A Chip | 2013 | 289 |
| 37 | High Fidelity of Murine Hepatitis Virus Replication Is Decreased in nsp14 Exoribonuclease Mutants | Journal of Virology | 2007 | 284 |
| 38 | The multifaceted role of fibrinogen in tissue injury and inflammation | Blood | 2019 | 279 |
| 39 | Neurologic Involvement in Children and Adolescents Hospitalized in the United States for COVID-19 or Multisystem Inflammatory Syndrome | JAMA Neurology | 2021 | 276 |
| 40 | Imprinting-Mutation Mechanisms in Prader-Willi Syndrome | American Journal of Human Genetics | 1999 | 262 |
| 41 | Localization of the gene for familial primary pulmonary hypertension to chromosome 2q31–32 | Nature Genetics | 1997 | 260 |
| 42 | Neonatal Abstinence Syndrome and Maternal Opioid-Related Diagnoses in the US, 2010-2017 | JAMA - Journal of the American Medical Association | 2021 | 260 |
| 43 | Evaluation of candidate vaccine approaches for MERS-CoV | Nature Communications | 2015 | 258 |
| 44 | The Relationship between Executive Function and Obesity in Children and Adolescents: A Systematic Literature Review | Journal of Obesity | 2013 | 257 |
| 45 | Immediate Hypersensitivity to Polyethylene Glycols and Polysorbates: More Common Than We Have Recognized | Journal of Allergy and Clinical Immunology: in Practice | 2019 | 257 |
| 46 | Rhinovirus‐Associated Hospitalizations in Young Children | Journal of Infectious Diseases | 2007 | 255 |
| 47 | A novel group of rhinoviruses is associated with asthma hospitalizations | Journal of Allergy and Clinical Immunology | 2009 | 254 |
| 48 | MicroRNA regulation of cyclooxygenase-2 during embryo implantation | Proceedings of the National Academy of Sciences of the United States of America | 2007 | 250 |
| 49 | Rates of Hospitalizations for Respiratory Syncytial Virus, Human Metapneumovirus, and Influenza Virus in Older Adults | Journal of Infectious Diseases | 2012 | 250 |
| 50 | Manganese neurotoxicity and the role of reactive oxygen species | Free Radical Biology and Medicine | 2013 | 249 |
