Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen | Proceedings of the National Academy of Sciences of the United States of America | 2017 | 615 |
Passive transfer of modest titers of potent and broadly neutralizing anti-HIV monoclonal antibodies block SHIV infection in macaques | Journal of Experimental Medicine | 2014 | 245 |
Highly stable trimers formed by human immunodeficiency virus type 1 envelope glycoproteins fused with the trimeric motif of T4 bacteriophage fibritin | Journal of Virology | 2002 | 242 |
Vaccine-induced IgG antibodies to V1V2 regions of multiple HIV-1 subtypes correlate with decreased risk of HIV-1 infection | PLoS ONE | 2014 | 209 |
Preferential infection and depletion of Mycobacterium tuberculosis-specific CD4 T cells after HIV-1 infection | Journal of Experimental Medicine | 2010 | 188 |
HIV-1 causes CD4 cell death through DNA-dependent protein kinase during viral integration | Nature | 2013 | 173 |
Correlates of protective immunity for Ebola vaccines: implications for regulatory approval by the animal rule | Nature Reviews Microbiology | 2009 | 171 |
Myeloid and plasmacytoid dendritic cells transfer HIV-1 preferentially to antigen-specific CD4+ T cells | Journal of Experimental Medicine | 2005 | 168 |
Structure-based, targeted deglycosylation of HIV-1 gp120 and effects on neutralization sensitivity and antibody recognition | Virology | 2003 | 150 |
Selective recognition of oligomeric HIV-1 primary isolate envelope glycoproteins by potently neutralizing ligands requires efficient precursor cleavage | Virology | 2005 | 128 |
Follicular CD8 T cells accumulate in HIV infection and can kill infected cells in vitro via bispecific antibodies | Science Translational Medicine | 2017 | 106 |
Crystal structures of GII.10 and GII.12 norovirus protruding domains in complex with histo-blood group antigens reveal details for a potential site of vulnerability | Journal of Virology | 2011 | 101 |
MicroRNAs in colorectal carcinoma--from pathogenesis to therapy | Journal of Experimental and Clinical Cancer Research | 2016 | 78 |
Adenoviral vector-based strategies against infectious disease and cancer | Human Vaccines and Immunotherapeutics | 2016 | 66 |
Preferential infection shortens the life span of human immunodeficiency virus-specific CD4+ T cells in vivo | Journal of Virology | 2006 | 62 |
Analysis of the human immunodeficiency virus type 1 gp41 membrane proximal external region arrayed on hepatitis B surface antigen particles | Virology | 2008 | 60 |
A virus-like particle based bivalent vaccine confers dual protection against enterovirus 71 and coxsackievirus A16 infections in mice | Vaccine | 2014 | 59 |
Recombinant Chimpanzee Adenovirus Vaccine AdC7-M/E Protects against Zika Virus Infection and Testis Damage | Journal of Virology | 2018 | 55 |
Altered Glycosylation Patterns Increase Immunogenicity of a Subunit Hepatitis C Virus Vaccine, Inducing Neutralizing Antibodies Which Confer Protection in Mice | Journal of Virology | 2016 | 48 |
High-yield production of recombinant virus-like particles of enterovirus 71 in Pichia pastoris and their protective efficacy against oral viral challenge in mice | Vaccine | 2015 | 41 |
Transcutaneous immunization via rapidly dissolvable microneedles protects against hand-foot-and-mouth disease caused by enterovirus 71 | Journal of Controlled Release | 2016 | 37 |
Development of novel vaccine vectors: Chimpanzee adenoviral vectors | Human Vaccines and Immunotherapeutics | 2018 | 36 |
Structural Basis for Recognition of Human Enterovirus 71 by a Bivalent Broadly Neutralizing Monoclonal Antibody | PLoS Pathogens | 2016 | 36 |
Recent advances of oncolytic virus in cancer therapy | Human Vaccines and Immunotherapeutics | 2020 | 34 |
Rapid Identification of the Receptor-Binding Specificity of Influenza A Viruses by Fluorogenic Glycofoldamers | Angewandte Chemie - International Edition | 2016 | 33 |