| # | Title | Journal | Year | Citations |
|---|
| 1 | Design and validation of a histological scoring system for nonalcoholic fatty liver disease | Hepatology | 2005 | 8,518 |
| 2 | A lipidomic analysis of nonalcoholic fatty liver disease | Hepatology | 2007 | 1,096 |
| 3 | Prevalence and Characteristics of the Metabolic Syndrome in Women with Polycystic Ovary Syndrome | Journal of Clinical Endocrinology and Metabolism | 2005 | 811 |
| 4 | Decreases in Ovarian Cytochrome P450c17α Activity and Serum Free Testosterone after Reduction of Insulin Secretion in Polycystic Ovary Syndrome | New England Journal of Medicine | 1996 | 696 |
| 5 | Nonalcoholic steatohepatitis is associated with altered hepatic MicroRNA expression | Hepatology | 2008 | 589 |
| 6 | The plasma lipidomic signature of nonalcoholic steatohepatitis | Hepatology | 2009 | 521 |
| 7 | Activation and Dysregulation of the Unfolded Protein Response in Nonalcoholic Fatty Liver Disease | Gastroenterology | 2008 | 518 |
| 8 | Similarities and differences in outcomes of cirrhosis due to nonalcoholic steatohepatitis and hepatitis C | Hepatology | 2006 | 458 |
| 9 | Handwashing Compliance by Health Care Workers | Archives of Internal Medicine | 2000 | 402 |
| 10 | Insulin Stimulates Testosterone Biosynthesis by Human Thecal Cells from Women with Polycystic Ovary Syndrome by Activating Its Own Receptor and Using Inositolglycan Mediators as the Signal Transduction System1 | Journal of Clinical Endocrinology and Metabolism | 1998 | 397 |
| 11 | Suppression of Serum Insulin by Diazoxide Reduces Serum Testosterone Levels in Obese Women with Polycystic Ovary Syndrome* | Journal of Clinical Endocrinology and Metabolism | 1989 | 335 |
| 12 | National Surveillance of Nosocomial Blood Stream Infection Due to Species of Candida Other than Candida albicans: Frequency of Occurrence and Antifungal Susceptibility in the SCOPE Program | Diagnostic Microbiology and Infectious Disease | 1998 | 331 |
| 13 | Metformin increases the ovulatory rate and pregnancy rate from clomiphene citrate in patients with polycystic ovary syndrome who are resistant to clomiphene citrate alone | Fertility and Sterility | 2001 | 319 |
| 14 | Lean Women with Polycystic Ovary Syndrome Respond to Insulin Reduction with Decreases in Ovarian P450c17α Activity and Serum Androgens1 | Journal of Clinical Endocrinology and Metabolism | 1997 | 315 |
| 15 | Phosphodiesterase-5 Inhibition With Sildenafil Attenuates Cardiomyocyte Apoptosis and Left Ventricular Dysfunction in a Chronic Model of Doxorubicin Cardiotoxicity | Circulation | 2005 | 310 |
| 16 | Phosphodiesterase-5 Inhibitor Sildenafil Preconditions Adult Cardiac Myocytes against Necrosis and Apoptosis | Journal of Biological Chemistry | 2005 | 304 |
| 17 | Portal Hypertension and Its Complications | Gastroenterology | 2008 | 303 |
| 18 | POSITION STATEMENT: Glucose Intolerance in Polycystic Ovary Syndrome—A Position Statement of the Androgen Excess Society | Journal of Clinical Endocrinology and Metabolism | 2007 | 301 |
| 19 | Intestinal Barrier Dysfunction, LPS Translocation, and Disease Development | Journal of the Endocrine Society | 2020 | 291 |
| 20 | Sepsis-induced cholestasis | Hepatology | 2007 | 271 |
| 21 | Development of a new, more sensitive immunoassay for human tryptase: Use in systemic anaphylaxis | Journal of Clinical Immunology | 1994 | 257 |
| 22 | Signal Detectability | Medical Decision Making | 1991 | 233 |
| 23 | Antimicrobial Susceptibility and Selection of Resistance Among Staphylococcus epidermidis Isolates Recovered from Patients with Infections of Indwelling Foreign Devices | Antimicrobial Agents and Chemotherapy | 1978 | 224 |
| 24 | Laboratory Investigation of Deaths Due to Anaphylaxis | Journal of Forensic Sciences | 1991 | 216 |
| 25 | Portosystemic encephalopathy after transjugular intrahepatic portosystemic shunt: Results of a prospective controlled study*1 | Hepatology | 1994 | 212 |
| 26 | Strategies for the use of insulin-sensitizing drugs to treat infertility in women with polycystic ovary syndrome | Fertility and Sterility | 2002 | 208 |
| 27 | Availability, Wishful Thinking, and Physicians' Diagnostic Judgments for Patients with Suspected Bacteremia | Medical Decision Making | 1991 | 204 |
| 28 | Improving stem cell mobilization strategies: future directions | Bone Marrow Transplantation | 2009 | 194 |
| 29 | HIF-1 activation attenuates postischemic myocardial injury: role for heme oxygenase-1 in modulating microvascular chemokine generation | American Journal of Physiology - Heart and Circulatory Physiology | 2005 | 190 |
| 30 | Bacteremias: A Leading Cause of Death | Archives of Medical Research | 2005 | 184 |
| 31 | Rapamycin confers preconditioning-like protection against ischemia–reperfusion injury in isolated mouse heart and cardiomyocytes | Journal of Molecular and Cellular Cardiology | 2006 | 181 |
| 32 | Attitudes of BCLS instructors about mouth-to-mouth resuscitation during the AIDS epidemic | Annals of Emergency Medicine | 1990 | 173 |
| 33 | A Novel Role of MicroRNA in Late Preconditioning | Circulation Research | 2009 | 173 |
| 34 | Differences in initial treatment patterns and outcomes of lung cancer in the elderly | Lung Cancer | 1995 | 160 |
| 35 | Prediction of survival of critically ill patients by admission comorbidity | Journal of Clinical Epidemiology | 1996 | 158 |
| 36 | Hypoxia Inducible Factor-1 Activation by Prolyl 4-Hydroxylase-2 Gene Silencing Attenuates Myocardial Ischemia Reperfusion Injury | Circulation Research | 2006 | 156 |
| 37 | Curcumin improves intestinal barrier function: modulation of intracellular signaling, and organization of tight junctions | American Journal of Physiology - Cell Physiology | 2017 | 153 |
| 38 | Role of Hyperinsulinemia in the Pathogenesis of the Polycystic Ovary Syndrome, and Its Clinical Implications | Seminars in Reproductive Medicine | 1997 | 151 |
| 39 | The economics of nosocomial infections | Journal of Hospital Infection | 1995 | 149 |
| 40 | Relationship between cardiac output and the end-trial carbon dioxide tension | Annals of Emergency Medicine | 1990 | 147 |
| 41 | Dose-dependent vasopressor response to epinephrine during CPR in human beings | Annals of Emergency Medicine | 1989 | 144 |
| 42 | Reproductive Factors, Smoking, and the Risk for Rheumatoid Arthritis | Epidemiology | 1990 | 144 |
| 43 | Bloodstream Infections Due to Candida Species in the Intensive Care Unit: Identifying Especially High-Risk Patients to Determine Prevention Strategies | Clinical Infectious Diseases | 2005 | 135 |
| 44 | Prevalence of Polycystic Ovary Syndrome Among Premenopausal Women With Type 2 Diabetes | Diabetes Care | 2001 | 129 |
| 45 | Recent advances in nonalcoholic fatty liver disease | Current Opinion in Gastroenterology | 2010 | 126 |
| 46 | Oral Supplementation with Non-Absorbable Antibiotics or Curcumin Attenuates Western Diet-Induced Atherosclerosis and Glucose Intolerance in LDLR−/− Mice – Role of Intestinal Permeability and Macrophage Activation | PLoS ONE | 2014 | 125 |
| 47 | Circulating ICAM-1 is increased in septic shock. | American Journal of Respiratory and Critical Care Medicine | 1995 | 124 |
| 48 | Insulin regulation of human ovarian androgens | Human Reproduction | 1997 | 124 |
| 49 | NADPH Oxidase-Mediated Triggering of Inflammasome Activation in Mouse Podocytes and Glomeruli During Hyperhomocysteinemia | Antioxidants and Redox Signaling | 2013 | 124 |
| 50 | ERK phosphorylation mediates sildenafil-induced myocardial protection against ischemia-reperfusion injury in mice | American Journal of Physiology - Heart and Circulatory Physiology | 2009 | 121 |
