| # | Title | Journal | Year | Citations |
|---|
| 1 | A penetration-aspiration scale | Dysphagia | 1996 | 2,116 |
| 2 | Alterations in Brain and Immune Function Produced by Mindfulness Meditation | Psychosomatic Medicine | 2003 | 1,964 |
| 3 | The Risk of Bloodstream Infection in Adults With Different Intravascular Devices: A Systematic Review of 200 Published Prospective Studies | Mayo Clinic Proceedings | 2006 | 1,273 |
| 4 | Clinical and economic consequences of ventilator-associated pneumonia: A systematic review | Critical Care Medicine | 2005 | 993 |
| 5 | Multilineage Differentiation from Human Embryonic Stem Cell Lines | Stem Cells | 2001 | 876 |
| 6 | Diagnosis of Invasive Aspergillosis Using a Galactomannan Assay: A Meta-Analysis | Clinical Infectious Diseases | 2006 | 846 |
| 7 | Association of Sleep Apnea and Type II Diabetes | American Journal of Respiratory and Critical Care Medicine | 2005 | 670 |
| 8 | Preserved Cognition in Patients With Early Alzheimer Disease and Amnestic Mild Cognitive Impairment During Treatment With Rosiglitazone: A Preliminary Study | American Journal of Geriatric Psychiatry | 2005 | 498 |
| 9 | Meta-analysis of Randomized Control Trials Addressing Brief Interventions in Heavy Alcohol Drinkers | Journal of General Internal Medicine | 1997 | 482 |
| 10 | Use of Human Immunodeficiency Virus-1 Protease Inhibitors Is Associated With Atherogenic Lipoprotein Changes and Endothelial Dysfunction | Circulation | 2001 | 454 |
| 11 | An attachable silver-impregnated cuff for prevention of infection with central venous catheters: A prospective randomized multicenter trial | American Journal of Medicine | 1988 | 449 |
| 12 | Adverse effects of isolation in hospitalised patients: a systematic review | Journal of Hospital Infection | 2010 | 415 |
| 13 | Does combination antimicrobial therapy reduce mortality in Gram-negative bacteraemia? A meta-analysis | Lancet Infectious Diseases, The | 2004 | 398 |
| 14 | Adverse Effects of Low Dose Amiodarone: A Meta-Analysis | Journal of the American College of Cardiology | 1997 | 389 |
| 15 | CLINICAL GUIDELINE: Diagnosing Syncope: Part 1: Value of History, Physical Examination, and Electrocardiography | Annals of Internal Medicine | 1997 | 384 |
| 16 | Rhinovirus upper respiratory infection increases airway hyperreactivity and late asthmatic reactions. | Journal of Clinical Investigation | 1989 | 371 |
| 17 | The pathogenesis and epidemiology of catheter-related infection with pulmonary artery Swan-Ganz catheters: A prospective study utilizing molecular subtyping | American Journal of Medicine | 1991 | 365 |
| 18 | Growing tissues in microgravity | Nature Medicine | 1998 | 349 |
| 19 | Managed care, time pressure, and physician job satisfaction: Results from the physician worklife study | Journal of General Internal Medicine | 2000 | 348 |
| 20 | Catheter-Associated Urinary Tract Infection Is Rarely Symptomatic | Archives of Internal Medicine | 2000 | 341 |
| 21 | Diagnosing Bacterial Respiratory Infection by Bronchoalveolar Lavage | Journal of Infectious Diseases | 1987 | 303 |
| 22 | The Risk of Infection after Nasal Colonization with Staphylococcus Aureus | American Journal of Medicine | 2008 | 300 |
| 23 | CLINICAL GUIDELINE: Diagnosing Syncope: Part 2: Unexplained Syncope | Annals of Internal Medicine | 1997 | 289 |
| 24 | Risk of Catheter-Related Bloodstream Infection With Peripherally Inserted Central Venous Catheters Used in Hospitalized Patients | Chest | 2005 | 285 |
| 25 | Direct human health risks of increased atmospheric carbon dioxide | Nature Sustainability | 2019 | 279 |
| 26 | Meta-analysis of randomized control trials addressing brief interventions in heavy alcohol drinkers | Journal of General Internal Medicine | 1997 | 274 |
| 27 | Topical chlorhexidine for prevention of ventilator-associated pneumonia: A meta-analysis* | Critical Care Medicine | 2007 | 267 |
| 28 | In Vivo Pharmacodynamics of a New Oxazolidinone (Linezolid) | Antimicrobial Agents and Chemotherapy | 2002 | 258 |
| 29 | Risk of Hemolytic Uremic Syndrome After Antibiotic Treatment of Escherichia coli O157:H7 Enteritis | JAMA - Journal of the American Medical Association | 2002 | 251 |
| 30 | Reduction in nosocomial infection with improved hand hygiene in intensive care units of a tertiary care hospital in Argentina | American Journal of Infection Control | 2005 | 248 |
| 31 | Nonerosive Reflux Disease— Current Concepts and Dilemmas | American Journal of Gastroenterology | 2001 | 246 |
| 32 | The Promise of Novel Technology for the Prevention of Intravascular Device–Related Bloodstream Infection. I. Pathogenesis and Short‐Term Devices | Clinical Infectious Diseases | 2002 | 239 |
| 33 | A Candidate Gene Approach Identifies the CHRNA5-A3-B4 Region as a Risk Factor for Age-Dependent Nicotine Addiction | PLoS Genetics | 2008 | 239 |
| 34 | Comparative analysis of physiologic responses to three different maximal graded exercise test protocols in healthy women | American Heart Journal | 1982 | 238 |
| 35 | A prospective, randomized, double-blind study of trimethoprim-sulfamethoxazole for prophylaxis of infection in renal transplantation: Clinical efficacy, absorption of trimethoprim-sulfamethoxazole, effects on the microflora, and the cost-benefit of prophylaxis | American Journal of Medicine | 1990 | 234 |
| 36 | Non-Esterified Fatty Acids in the Blood of Obese and Lean Subjects | American Journal of Clinical Nutrition | 1960 | 226 |
| 37 | A Review of Risk Factors for Catheter-Related Bloodstream Infection Caused by Percutaneously Inserted, Noncuffed Central Venous Catheters | Medicine (United States) | 2002 | 225 |
| 38 | Phase I Pharmacokinetic and Pharmacodynamic Study of Recombinant Human Endostatin in Patients With Advanced Solid Tumors | Journal of Clinical Oncology | 2003 | 222 |
| 39 | Innate immune responses to rhinovirus are reduced by the high-affinity IgE receptor in allergic asthmatic children | Journal of Allergy and Clinical Immunology | 2012 | 216 |
| 40 | Intrinsic factor studies: II. The effect of gastric juice on the urinary excretion of radioactivity after the oral administration of radioactive vitamin B12 | Translational Research | 2004 | 211 |
| 41 | Comparison among the perforation rates of Maloney, balloon, and Savary dilation of esophageal strictures | Gastrointestinal Endoscopy | 2000 | 205 |
| 42 | Background Fluctuation of Kidney Function Versus Contrast-Induced Nephrotoxicity | American Journal of Roentgenology | 2009 | 199 |
| 43 | Visceral Obesity and Insulin Resistance Are Associated with Plasma Aldosterone Levels in Women | Obesity | 1999 | 197 |
| 44 | A cost-effectiveness and cost-utility analysis of radiosurgery vs. resection for single-brain metastases | International Journal of Radiation Oncology Biology Physics | 1997 | 195 |
| 45 | Reduction of Nosocomial Infection during Pediatric Intensive Care by Protective Isolation | New England Journal of Medicine | 1989 | 191 |
| 46 | Measuring Physician Job Satisfaction in a Changing Workplace and a Challenging Environment | Medical Care | 1999 | 186 |
| 47 | Characterization and Quantitation of the Pharmacodynamics of Fluconazole in a Neutropenic Murine Disseminated Candidiasis Infection Model | Antimicrobial Agents and Chemotherapy | 1999 | 184 |
| 48 | Sex biology contributions to vulnerability to Alzheimer's disease: A think tank convened by the Women's Alzheimer's Research Initiative | Alzheimer's and Dementia | 2016 | 180 |
| 49 | Omalizumab in Asthma: An Update on Recent Developments | Journal of Allergy and Clinical Immunology: in Practice | 2014 | 179 |
| 50 | Molecular modeling, organ culture and reverse genetics for a newly identified human rhinovirus C | Nature Medicine | 2011 | 177 |
