| # | Title | Journal | Year | Citations |
|---|
| 1 | Projected number of people with Parkinson disease in the most populous nations, 2005 through 2030 | Neurology | 2007 | 1,944 |
| 2 | Multiple Wearable Sensors in Parkinson and Huntington Disease Individuals: A Pilot Study in Clinic and at Home | Digital Biomarkers | 2017 | 1,794 |
| 3 | Effects of Tocopherol and Deprenyl on the Progression of Disability in Early Parkinson's Disease | New England Journal of Medicine | 1993 | 1,283 |
| 4 | Differences in the pattern of hippocampal neuronal loss in normal ageing and Alzheimer's disease | Lancet, The | 1994 | 1,142 |
| 5 | Uniquely Hominid Features of Adult Human Astrocytes | Journal of Neuroscience | 2009 | 1,112 |
| 6 | A call for transparent reporting to optimize the predictive value of preclinical research | Nature | 2012 | 1,055 |
| 7 | Huntington disease | Nature Reviews Disease Primers | 2015 | 1,031 |
| 8 | Trinucleotide repeat length instability and age of onset in Huntington's disease | Nature Genetics | 1993 | 1,008 |
| 9 | A Unifying Genetic Model for Facioscapulohumeral Muscular Dystrophy | Science | 2010 | 638 |
| 10 | The Parkinson Pandemic—A Call to Action | JAMA Neurology | 2018 | 584 |
| 11 | Digenic inheritance of an SMCHD1 mutation and an FSHD-permissive D4Z4 allele causes facioscapulohumeral muscular dystrophy type 2 | Nature Genetics | 2012 | 582 |
| 12 | HIV-associated cognitive impairment before and after the advent of combination therapy | Journal of NeuroVirology | 2002 | 555 |
| 13 | Interferon-α/β-mediated innate immune mechanisms in dermatomyositis | Annals of Neurology | 2005 | 530 |
| 14 | Forebrain Engraftment by Human Glial Progenitor Cells Enhances Synaptic Plasticity and Learning in Adult Mice | Cell Stem Cell | 2013 | 517 |
| 15 | Heterogeneity of Astrocytic Form and Function | Methods in Molecular Biology | 2012 | 480 |
| 16 | Technology in Parkinson's disease: Challenges and opportunities | Movement Disorders | 2016 | 464 |
| 17 | P2X7 receptor inhibition improves recovery after spinal cord injury | Nature Medicine | 2004 | 454 |
| 18 | Failure of MBNL1-dependent post-natal splicing transitions in myotonic dystrophy | Human Molecular Genetics | 2006 | 445 |
| 19 | Beta/Gamma EEG Activity in Patients with Primary and Secondary Insomnia and Good Sleeper Controls | Sleep | 2001 | 409 |
| 20 | Definition and classification of hyperkinetic movements in childhood | Movement Disorders | 2010 | 374 |
| 21 | Overexpression of nef as a marker for restricted HIV‐1 infection of astrocytes in postmortem pediatric central nervous tissues | Neurology | 1994 | 357 |
| 22 | Stem and progenitor cell–based therapy of the human central nervous system | Nature Biotechnology | 2005 | 346 |
| 23 | Inhibitors of leucine-rich repeat kinase-2 protect against models of Parkinson's disease | Nature Medicine | 2010 | 342 |
| 24 | Hand function: peripheral and central constraints on performance | Journal of Applied Physiology | 2004 | 340 |
| 25 | HIV‐Associated Disease of the Nervous System: Review of Nomenclature and Proposal for Neuropathology‐Based Terminology | Brain Pathology | 1991 | 323 |
| 26 | A phase 3 trial of extended release oral dalfampridine in multiple sclerosis | Annals of Neurology | 2010 | 320 |
| 27 | Regulated Release and Polarized Localization of Brain-Derived Neurotrophic Factor in Hippocampal Neurons | Molecular and Cellular Neurosciences | 1996 | 319 |
| 28 | Mutations in a Gene Encoding a Novel Protein Containing a Phosphotyrosine-Binding Domain Cause Type 2 Cerebral Cavernous Malformations | American Journal of Human Genetics | 2003 | 319 |
| 29 | Using Smartphones and Machine Learning to Quantify Parkinson Disease Severity | JAMA Neurology | 2018 | 303 |
| 30 | Platelet-activating factor: a candidate human immunodeficiency virus type 1-induced neurotoxin | Journal of Virology | 1994 | 301 |
| 31 | Neonatal Chimerization with Human Glial Progenitor Cells Can Both Remyelinate and Rescue the Otherwise Lethally Hypomyelinated Shiverer Mouse | Cell Stem Cell | 2008 | 293 |
| 32 | Myotonic Dystrophy | Neurologic Clinics | 2014 | 293 |
| 33 | Funding of US Biomedical Research, 2003-2008 | JAMA - Journal of the American Medical Association | 2010 | 291 |
| 34 | Detecting and monitoring the symptoms of Parkinson's disease using smartphones: A pilot study | Parkinsonism and Related Disorders | 2015 | 285 |
| 35 | MST Neurons Respond to Optic Flow and Translational Movement | Journal of Neurophysiology | 1998 | 284 |
| 36 | Mixed lineage kinase inhibitor CEP-1347 fails to delay disability in early Parkinson disease | Neurology | 2007 | 283 |
| 37 | Glioma Stem Cell Proliferation and Tumor Growth Are Promoted by Nitric Oxide Synthase-2 | Cell | 2011 | 280 |
| 38 | Reliability of the CMT neuropathy score (second version) in Charcot‐Marie‐Tooth disease | Journal of the Peripheral Nervous System | 2011 | 269 |
| 39 | Myotonic dystrophy patients have larger CTG expansions in skeletal muscle than in leukocytes | Annals of Neurology | 1994 | 259 |
| 40 | Serotonin syndrome and the combined use of deprenyl and an antidepressant in Parkinson's disease | Neurology | 1997 | 250 |
| 41 | Loss of MBNL Leads to Disruption of Developmentally Regulated Alternative Polyadenylation in RNA-Mediated Disease | Molecular Cell | 2014 | 248 |
| 42 | Activated Protein C Prevents Neuronal Apoptosis via Protease Activated Receptors 1 and 3 | Neuron | 2004 | 243 |
| 43 | Tourette syndrome deep brain stimulation: A review and updated recommendations | Movement Disorders | 2015 | 236 |
| 44 | Tumor necrosis factor-alpha mediated signaling in neuronal homeostasis and dysfunction | Cellular Signalling | 2010 | 235 |
| 45 | Epileptogenic effect of hypoxia in the immature rodent brain | Annals of Neurology | 1991 | 233 |
| 46 | N-Methyl-d-Aspartate Antagonists in the Treatment of Parkinson's Disease | Archives of Neurology | 1991 | 227 |
| 47 | Neurological Diseases as Primary Gliopathies: A Reassessment of Neurocentrism | ASN Neuro | 2012 | 217 |
| 48 | Splicing biomarkers of disease severity in myotonic dystrophy | Annals of Neurology | 2013 | 215 |
| 49 | A roadmap for implementation of patient‐centered digital outcome measures in Parkinson's disease obtained using mobile health technologies | Movement Disorders | 2019 | 213 |
| 50 | Quantitative assessment of motor fatigue and strength in MS | Neurology | 1999 | 211 |
