| # | Title | Journal | Year | Citations |
|---|
| 1 | The Glymphatic System: A Beginner’s Guide | Neurochemical Research | 2015 | 1,266 |
| 2 | A call for transparent reporting to optimize the predictive value of preclinical research | Nature | 2012 | 1,055 |
| 3 | The Incidence of Pediatric Cardiomyopathy in Two Regions of the United States | New England Journal of Medicine | 2003 | 722 |
| 4 | Impact of Primary Prophylaxis With Granulocyte Colony-Stimulating Factor on Febrile Neutropenia and Mortality in Adult Cancer Patients Receiving Chemotherapy: A Systematic Review | Journal of Clinical Oncology | 2007 | 639 |
| 5 | Thymine-Thymine Dimer Bypass by Yeast DNA Polymerase zeta | Science | 1996 | 633 |
| 6 | Garbage Truck of the Brain | Science | 2013 | 526 |
| 7 | Nerve Physiology | Hand Clinics | 2013 | 458 |
| 8 | Dysregulation of germinal centres in autoimmune disease | Nature Reviews Immunology | 2009 | 389 |
| 9 | Ultra-fast magnetic resonance encephalography of physiological brain activity – Glymphatic pulsation mechanisms? | Journal of Cerebral Blood Flow and Metabolism | 2016 | 283 |
| 10 | Standardizing Flow Cytometry Immunophenotyping Analysis from the Human ImmunoPhenotyping Consortium | Scientific Reports | 2016 | 240 |
| 11 | Causal signals between codon bias, mRNA structure, and the efficiency of translation and elongation | Molecular Systems Biology | 2014 | 231 |
| 12 | Mitochondria as a Drug Target in Ischemic Heart Disease and Cardiomyopathy | Circulation Research | 2012 | 226 |
| 13 | Respiratory Syncytial Virus Uses CX3CR1 as a Receptor on Primary Human Airway Epithelial Cultures | PLoS Pathogens | 2015 | 215 |
| 14 | Contributions of the Na+/K+‐ATPase, NKCC1, and Kir4.1 to hippocampal K+ clearance and volume responses | Glia | 2014 | 207 |
| 15 | A management algorithm for adult patients with both brain oxygen and intracranial pressure monitoring: the Seattle International Severe Traumatic Brain Injury Consensus Conference (SIBICC) | Intensive Care Medicine | 2020 | 207 |
| 16 | A Perspective: Engineering Periosteum for Structural Bone Graft Healing | Clinical Orthopaedics and Related Research | 2008 | 194 |
| 17 | Traumatic Brain Injury Pathophysiology and Treatments: Early, Intermediate, and Late Phases Post-Injury | International Journal of Molecular Sciences | 2014 | 194 |
| 18 | Neurodevelopmental effects of maternal nutritional status and exposure to methylmercury from eating fish during pregnancy | NeuroToxicology | 2008 | 183 |
| 19 | Blood–Spinal Cord Barrier Pericyte Reductions Contribute to Increased Capillary Permeability | Journal of Cerebral Blood Flow and Metabolism | 2012 | 171 |
| 20 | An integrative view of cisplatin-induced renal and cardiac toxicities: Molecular mechanisms, current treatment challenges and potential protective measures | Toxicology | 2016 | 163 |
| 21 | Ribonuclear inclusions in skeletal muscle in myotonic dystrophy types 1 and 2 | Annals of Neurology | 2003 | 160 |
| 22 | Nasal and sinus symptoms and chronic rhinosinusitis in a population-based sample | Allergy: European Journal of Allergy and Clinical Immunology | 2017 | 160 |
| 23 | The ACTTION-American Pain Society Pain Taxonomy (AAPT): An Evidence-Based and Multidimensional Approach to Classifying Chronic Pain Conditions | Journal of Pain | 2014 | 159 |
| 24 | Mechanisms of cognitive dysfunction in CKD | Nature Reviews Nephrology | 2020 | 159 |
| 25 | The impact of exercise during adjuvant radiotherapy for breast cancer on fatigue and quality of life: A systematic review and meta-analysis | Breast | 2017 | 145 |
| 26 | Comparing Inhaled Ultrafine versus Fine Zinc Oxide Particles in Healthy Adults | American Journal of Respiratory and Critical Care Medicine | 2005 | 143 |
| 27 | nNOS and eNOS modulate cGMP formation and vascular response in contracting fast-twitch skeletal muscle | Physiological Genomics | 2000 | 138 |
| 28 | Developmental Control of the Melanocortin-4 Receptor by MRAP2 Proteins in Zebrafish | Science | 2013 | 136 |
| 29 | Beyond the "Psychosomatic Family": A Biobehavioral Family Model of Pediatric Illness | Family Process | 1993 | 132 |
| 30 | Phosphorylation of Inositol 1,4,5-Trisphosphate Receptors in Parotid Acinar Cells | Journal of Biological Chemistry | 2002 | 130 |
| 31 | Current Status of Therapeutic Approaches against Peripheral Nerve Injuries: A Detailed Story from Injury to Recovery | International Journal of Biological Sciences | 2020 | 129 |
| 32 | Neuroinflammation and anti-inflammatory therapy for Alzheimer’s disease | Advanced Drug Delivery Reviews | 2002 | 126 |
| 33 | Traumatic Rib Injury: Patterns, Imaging Pitfalls, Complications, and Treatment | Radiographics | 2017 | 122 |
| 34 | Lesions from patients with sporadic cerebral cavernous malformations harbor somatic mutations in the CCM genes: evidence for a common biochemical pathway for CCM pathogenesis | Human Molecular Genetics | 2014 | 117 |
| 35 | Sex, Age, and Hunger Regulate Behavioral Prioritization through Dynamic Modulation of Chemoreceptor Expression | Current Biology | 2014 | 116 |
| 36 | Transcriptome-wide dynamics of RNA pseudouridylation | Nature Reviews Molecular Cell Biology | 2015 | 107 |
| 37 | 4D-Printed Dynamic Materials in Biomedical Applications: Chemistry, Challenges, and Their Future Perspectives in the Clinical Sector | Journal of Medicinal Chemistry | 2020 | 107 |
| 38 | Characterization of Components of the Staphylococcus aureus mRNA Degradosome Holoenzyme-Like Complex | Journal of Bacteriology | 2011 | 104 |
| 39 | Dental caries – not just holes in teeth! A perspective | Molecular Oral Microbiology | 2016 | 103 |
| 40 | Incidence of patients with bone metastases at diagnosis of solid tumors in adults: a large population-based study | Annals of Translational Medicine | 2020 | 101 |
| 41 | The use of serum levels of cardiac troponin T to compare the protective activity of dexrazoxane against doxorubicin- and mitoxantrone-induced cardiotoxicity | Cancer Chemotherapy and Pharmacology | 2001 | 98 |
| 42 | BMP signaling stimulates chondrocyte maturation and the expression of Indian hedgehog | Journal of Orthopaedic Research | 2001 | 98 |
| 43 | Management of Effort Thrombosis of the Subclavian Vein: Today's Treatment | Annals of Vascular Surgery | 2007 | 92 |
| 44 | Suicide Later in Life | American Journal of Preventive Medicine | 2014 | 92 |
| 45 | Esophagectomy for High Grade Dysplasia is Safe, Curative, and Results in Good Alimentary Outcome | Journal of Gastrointestinal Surgery | 2007 | 91 |
| 46 | G(-) Anaerobes-Reactive CD4+ T-Cells Trigger RANKL-Mediated Enhanced Alveolar Bone Loss in Diabetic NOD Mice | Diabetes | 2005 | 90 |
| 47 | Prevalence and Patterns of Occult Hip Fractures and Mimics Revealed by MRI | American Journal of Roentgenology | 2004 | 89 |
| 48 | A systematic review of dental late effects in survivors of childhood cancer | Pediatric Blood and Cancer | 2014 | 89 |
| 49 | Skeletal muscle contractions stimulate cGMP formation and attenuate vascular smooth muscle myosin phosphorylation via nitric oxide | FEBS Letters | 1998 | 87 |
| 50 | Variability Among US Intensive Care Units in Managing the Care of Patients Admitted With Preexisting Limits on Life-Sustaining Therapies | JAMA Internal Medicine | 2015 | 85 |
