| # | Title | Journal | Year | Citations |
|---|
| 1 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 2 | Functions of RANKL/RANK/OPG in bone modeling and remodeling | Archives of Biochemistry and Biophysics | 2008 | 1,335 |
| 3 | Calcium-dependent phospholipid scrambling by TMEM16F | Nature | 2010 | 802 |
| 4 | Defining inflammatory cell states in rheumatoid arthritis joint synovial tissues by integrating single-cell transcriptomics and mass cytometry | Nature Immunology | 2019 | 760 |
| 5 | Biology of RANK, RANKL, and osteoprotegerin | Arthritis Research and Therapy | 2007 | 674 |
| 6 | MicroRNA-204 Regulates Runx2 Protein Expression and Mesenchymal Progenitor Cell Differentiation | Stem Cells | 2010 | 525 |
| 7 | Health Care–Associated Infection After Red Blood Cell Transfusion | JAMA - Journal of the American Medical Association | 2014 | 513 |
| 8 | CRTAP Is Required for Prolyl 3- Hydroxylation and Mutations Cause Recessive Osteogenesis Imperfecta | Cell | 2006 | 465 |
| 9 | c-MAF-dependent regulatory T cells mediate immunological tolerance to a gut pathobiont | Nature | 2018 | 379 |
| 10 | NF-κB p50 and p52 Regulate Receptor Activator of NF-κB Ligand (RANKL) and Tumor Necrosis Factor-induced Osteoclast Precursor Differentiation by Activating c-Fos and NFATc1 | Journal of Biological Chemistry | 2007 | 364 |
| 11 | Dimorphic effects of Notch signaling in bone homeostasis | Nature Medicine | 2008 | 361 |
| 12 | Neuroendocrine differentiation in carcinoma of the prostate. Diagnostic, prognostic, and therapeutic implications | Cancer | 1992 | 336 |
| 13 | Evolving concepts in bone infection: redefining “biofilm”, “acute vs. chronic osteomyelitis”, “the immune proteome” and “local antibiotic therapy” | Bone Research | 2019 | 300 |
| 14 | Tumor Necrosis Factor-alpha and the Roles it Plays in Homeostatic and Degenerative Processes Within the Central Nervous System | Journal of NeuroImmune Pharmacology | 2012 | 284 |
| 15 | Hepatocytes: critical for glucose homeostasis | International Journal of Biochemistry and Cell Biology | 2004 | 278 |
| 16 | The megakaryocyte lineage originates from hemangioblast precursors and is an integral component both of primitive and of definitive hematopoiesis | Blood | 2007 | 259 |
| 17 | A clinical and immunologic study of blood transfusion and postoperative bacterial infection in spinal surgery | Transfusion | 1992 | 253 |
| 18 | The RANKL/RANK/OPG pathway | Current Osteoporosis Reports | 2007 | 251 |
| 19 | Infection or suspected infection after hip replacement surgery with autologous or homologous blood transfusions | Transfusion | 1991 | 249 |
| 20 | NF-κB-Mediated Regulation of Osteoclastogenesis | Endocrinology and Metabolism | 2015 | 243 |
| 21 | Neuroendocrine differentiation in human prostatic carcinoma | Human Pathology | 1992 | 229 |
| 22 | Autophagy protein ATG16L1 prevents necroptosis in the intestinal epithelium | Journal of Experimental Medicine | 2017 | 229 |
| 23 | Effects of transfusion on immune function. Cancer recurrence and infection | Archives of Pathology and Laboratory Medicine | 1994 | 207 |
| 24 | Reproducibility of histopathological subtypes and invasion in pulmonary adenocarcinoma. An international interobserver study | Modern Pathology | 2012 | 206 |
| 25 | Osteoclast precursors, RANKL/RANK, and immunology | Immunological Reviews | 2005 | 205 |
| 26 | National Academy of Clinical Biochemistry Laboratory Medicine Practice Guidelines: Recommendations for the Use of Laboratory Tests to Support Poisoned Patients Who Present to the Emergency Department | Clinical Chemistry | 2003 | 199 |
| 27 | PD‐1 inhibitor gastroenterocolitis: case series and appraisal of ‘immunomodulatory gastroenterocolitis’ | Histopathology | 2017 | 198 |
| 28 | Small Cell Carcinoma of the Prostate: An Immunohistochemical Study | American Journal of Surgical Pathology | 2006 | 190 |
| 29 | TNF.ALPHA. and pathologic bone resorption | Keio Journal of Medicine | 2005 | 188 |
| 30 | Selective Hepatic Insulin Resistance, VLDL Overproduction, and Hypertriglyceridemia | Arteriosclerosis, Thrombosis, and Vascular Biology | 2012 | 172 |
| 31 | Drp1 inhibition attenuates neurotoxicity and dopamine release deficits in vivo | Nature Communications | 2014 | 171 |
| 32 | Live-animal imaging of native haematopoietic stem and progenitor cells | Nature | 2020 | 171 |
| 33 | Adrenomyeloneuropathy | Journal of Neuropathology and Experimental Neurology | 2000 | 168 |
| 34 | Homologous blood transfusion as a risk factor for postoperative infection after coronary artery bypass graft operations | Journal of Thoracic and Cardiovascular Surgery | 1992 | 160 |
| 35 | Inhibition of lymphangiogenesis and lymphatic drainage via vascular endothelial growth factor receptor 3 blockade increases the severity of inflammation in a mouse model of chronic inflammatory arthritis | Arthritis and Rheumatism | 2009 | 155 |
| 36 | NF-κB p50 and p52 Expression Is Not Required for RANK-Expressing Osteoclast Progenitor Formation but Is Essential for RANK- and Cytokine-Mediated Osteoclastogenesis | Journal of Bone and Mineral Research | 2002 | 148 |
| 37 | Plasma amino acids profiles in children with autism: potential risk of nutritional deficiencies | Journal of Autism and Developmental Disorders | 2003 | 147 |
| 38 | Functions of nuclear factor κB in bone | Annals of the New York Academy of Sciences | 2010 | 147 |
| 39 | Teriparatide as a Chondroregenerative Therapy for Injury-Induced Osteoarthritis | Science Translational Medicine | 2011 | 145 |
| 40 | Distribution of disease at autopsy in 100 women with ovarian cancer | Human Pathology | 1988 | 141 |
| 41 | An association between decreased cardiopulmonary complications (transfusion‐related acute lung injury and transfusion‐associated circulatory overload) and implementation of universal leukoreduction of blood transfusions | Transfusion | 2010 | 141 |
| 42 | Definitive Hematopoiesis in the Yolk Sac Emerges from Wnt-Responsive Hemogenic Endothelium Independently of Circulation and Arterial Identity | Stem Cells | 2016 | 141 |
| 43 | Diagnostic criteria to distinguish hypocellular acute myeloid leukemia from hypocellular myelodysplastic syndromes and aplastic anemia: recommendations for a standardized approach | Haematologica | 2009 | 140 |
| 44 | Kupffer Cell-Dependent Hepatitis Occurs during Influenza Infection | American Journal of Pathology | 2006 | 139 |
| 45 | An association of soluble CD40 ligand (CD154) with adverse reactions to platelet transfusions | Transfusion | 2006 | 139 |
| 46 | Osteoclasts Have Multiple Roles in Bone in Addition to Bone Resorption | Critical Reviews in Eukaryotic Gene Expression | 2009 | 139 |
| 47 | Neuropathology of Mitochondrial Encephalomyopathies Due to Mitochondrial DNA Defects | Journal of Neuropathology and Experimental Neurology | 1993 | 138 |
| 48 | NF-κB p100 limits TNF-induced bone resorption in mice by a TRAF3-dependent mechanism | Journal of Clinical Investigation | 2009 | 137 |
| 49 | Increased lymphangiogenesis in joints of mice with inflammatory arthritis | Arthritis Research and Therapy | 2007 | 134 |
| 50 | Leukemia stem cells in a genetically defined murine model of blast-crisis CML | Blood | 2007 | 132 |
