| # | Title | Journal | Year | Citations |
|---|
| 1 | Discovery of common and rare genetic risk variants for colorectal cancer | Nature Genetics | 2019 | 377 |
| 2 | Determining Risk of Colorectal Cancer and Starting Age of Screening Based on Lifestyle, Environmental, and Genetic Factors | Gastroenterology | 2018 | 226 |
| 3 | Physical activity and risks of breast and colorectal cancer: a Mendelian randomisation analysis | Nature Communications | 2020 | 193 |
| 4 | Association of Aspirin and NSAID Use With Risk of Colorectal Cancer According to Genetic Variants | JAMA - Journal of the American Medical Association | 2015 | 171 |
| 5 | A Model to Determine Colorectal Cancer Risk Using Common Genetic Susceptibility Loci | Gastroenterology | 2015 | 129 |
| 6 | Novel Common Genetic Susceptibility Loci for Colorectal Cancer | Journal of the National Cancer Institute | 2019 | 129 |
| 7 | Genome-wide Modeling of Polygenic Risk Score in Colorectal Cancer Risk | American Journal of Human Genetics | 2020 | 124 |
| 8 | Estimating the heritability of colorectal cancer | Human Molecular Genetics | 2014 | 114 |
| 9 | Cumulative Burden of Colorectal Cancer–Associated Genetic Variants Is More Strongly Associated With Early-Onset vs Late-Onset Cancer | Gastroenterology | 2020 | 110 |
| 10 | Winner's Curse Correction and Variable Thresholding Improve Performance of Polygenic Risk Modeling Based on Genome-Wide Association Study Summary-Level Data | PLoS Genetics | 2016 | 98 |
| 11 | Identification of Susceptibility Loci and Genes for Colorectal Cancer Risk | Gastroenterology | 2016 | 97 |
| 12 | Circulating Levels of Insulin-like Growth Factor 1 and Insulin-like Growth Factor Binding Protein 3 Associate With Risk of Colorectal Cancer Based on Serologic and Mendelian Randomization Analyses | Gastroenterology | 2020 | 90 |
| 13 | Meta‐analysis of 16 studies of the association of alcohol with colorectal cancer | International Journal of Cancer | 2020 | 89 |
| 14 | Genome-Wide Diet-Gene Interaction Analyses for Risk of Colorectal Cancer | PLoS Genetics | 2014 | 81 |
| 15 | Adiposity, metabolites, and colorectal cancer risk: Mendelian randomization study | BMC Medicine | 2020 | 76 |
| 16 | MethyLight droplet digital PCR for detection and absolute quantification of infrequently methylated alleles | Epigenetics | 2015 | 63 |
| 17 | Common genetic variation and survival after colorectal cancer diagnosis: a genome-wide analysis | Carcinogenesis | 2016 | 62 |
| 18 | Gene–Environment Interaction Involving Recently Identified Colorectal Cancer Susceptibility Loci | Cancer Epidemiology Biomarkers and Prevention | 2014 | 48 |
| 19 | Genetic architectures of proximal and distal colorectal cancer are partly distinct | Gut | 2021 | 44 |
| 20 | DNA repair and cancer in colon and rectum: Novel players in genetic susceptibility | International Journal of Cancer | 2020 | 40 |
| 21 | Deciphering colorectal cancer genetics through multi-omic analysis of 100,204 cases and 154,587 controls of European and east Asian ancestries | Nature Genetics | 2023 | 39 |
| 22 | Genome-Wide Interaction Analyses between Genetic Variants and Alcohol Consumption and Smoking for Risk of Colorectal Cancer | PLoS Genetics | 2016 | 38 |
| 23 | Identifying Novel Susceptibility Genes for Colorectal Cancer Risk From a Transcriptome-Wide Association Study of 125,478 Subjects | Gastroenterology | 2021 | 36 |
| 24 | Pleiotropic effects of genetic risk variants for other cancers on colorectal cancer risk: PAGE, GECCO and CCFR consortia | Gut | 2014 | 35 |
| 25 | Mendelian randomization analysis of C-reactive protein on colorectal cancer risk | International Journal of Epidemiology | 2019 | 35 |
| 26 | Genome-Wide Search for Gene-Gene Interactions in Colorectal Cancer | PLoS ONE | 2012 | 35 |
| 27 | A Mixed-Effects Model for Powerful Association Tests in Integrative Functional Genomics | American Journal of Human Genetics | 2018 | 30 |
| 28 | Identification of a common variant with potential pleiotropic effect on risk of inflammatory bowel disease and colorectal cancer | Carcinogenesis | 2015 | 28 |
| 29 | Circulating bilirubin levels and risk of colorectal cancer: serological and Mendelian randomization analyses | BMC Medicine | 2020 | 28 |
| 30 | Relationship of prediagnostic body mass index with survival after colorectal cancer: Stage‐specific associations | International Journal of Cancer | 2016 | 26 |
| 31 | Influence of Smoking, Body Mass Index, and Other Factors on the Preventive Effect of Nonsteroidal Anti-Inflammatory Drugs on Colorectal Cancer Risk | Cancer Research | 2018 | 26 |
| 32 | CYP24A1 variant modifies the association between use of oestrogen plus progestogen therapy and colorectal cancer risk | British Journal of Cancer | 2016 | 18 |
| 33 | Genetic variants of adiponectin and risk of colorectal cancer | International Journal of Cancer | 2015 | 16 |
| 34 | Mendelian randomisation study of age at menarche and age at menopause and the risk of colorectal cancer | British Journal of Cancer | 2018 | 16 |
| 35 | Identifying colorectal cancer caused by biallelic MUTYH pathogenic variants using tumor mutational signatures | Nature Communications | 2022 | 15 |
| 36 | A Combined Proteomics and Mendelian Randomization Approach to Investigate the Effects of Aspirin-Targeted Proteins on Colorectal Cancer | Cancer Epidemiology Biomarkers and Prevention | 2021 | 10 |
| 37 | No Evidence of Gene–Calcium Interactions from Genome-Wide Analysis of Colorectal Cancer Risk | Cancer Epidemiology Biomarkers and Prevention | 2014 | 9 |
| 38 | Body mass index and molecular subtypes of colorectal cancer | Journal of the National Cancer Institute | 2023 | 9 |
| 39 | Fine-Mapping of Common Genetic Variants Associated with Colorectal Tumor Risk Identified Potential Functional Variants | PLoS ONE | 2016 | 8 |
| 40 | Enrichment of colorectal cancer associations in functional regions: Insight for using epigenomics data in the analysis of whole genome sequence-imputed GWAS data | PLoS ONE | 2017 | 8 |
| 41 | Association between Smoking and Molecular Subtypes of Colorectal Cancer | JNCI Cancer Spectrum | 2021 | 8 |
| 42 | Prognostic role of detailed colorectal location and tumor molecular features: analyses of 13,101 colorectal cancer patients including 2994 early-onset cases | Journal of Gastroenterology | 2023 | 7 |
| 43 | Genetically Predicted Circulating C-Reactive Protein Concentration and Colorectal Cancer Survival: A Mendelian Randomization Consortium Study | Cancer Epidemiology Biomarkers and Prevention | 2021 | 6 |
| 44 | Beyond GWAS of Colorectal Cancer: Evidence of Interaction with Alcohol Consumption and Putative Causal Variant for the 10q24.2 Region | Cancer Epidemiology Biomarkers and Prevention | 2022 | 6 |
| 45 | Telomere Maintenance Variants and Survival after Colorectal Cancer: Smoking- and Sex-Specific Associations | Cancer Epidemiology Biomarkers and Prevention | 2020 | 5 |
| 46 | Response to Li and Hopper | American Journal of Human Genetics | 2021 | 5 |
| 47 | Salicylic Acid and Risk of Colorectal Cancer: A Two-Sample Mendelian Randomization Study | Nutrients | 2021 | 3 |
| 48 | Genetic variants associated with circulating C‐reactive protein levels and colorectal cancer survival: Sex‐specific and lifestyle factors specific associations | International Journal of Cancer | 2022 | 2 |
| 49 | Genetic Predictors of Circulating 25-Hydroxyvitamin D and Prognosis after Colorectal Cancer | Cancer Epidemiology Biomarkers and Prevention | 2020 | 1 |
| 50 | Genetic Variants in the Regulatory T cell–Related Pathway and Colorectal Cancer Prognosis | Cancer Epidemiology Biomarkers and Prevention | 2020 | 1 |
