| # | Title | Journal | Year | Citations |
|---|
| 1 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
| 2 | ASSOCIATION BETWEEN SOCIAL MEDIA USE AND DEPRESSION AMONG U.S. YOUNG ADULTS | Depression and Anxiety | 2016 | 634 |
| 3 | Sterilization of granulomas is common in active and latent tuberculosis despite within-host variability in bacterial killing | Nature Medicine | 2014 | 442 |
| 4 | Understanding Latent Tuberculosis: A Moving Target | Journal of Immunology | 2010 | 384 |
| 5 | Influenza A Inhibits Th17-Mediated Host Defense against Bacterial Pneumonia in Mice | Journal of Immunology | 2011 | 312 |
| 6 | Microenvironments in Tuberculous Granulomas Are Delineated by Distinct Populations of Macrophage Subsets and Expression of Nitric Oxide Synthase and Arginase Isoforms | Journal of Immunology | 2013 | 292 |
| 7 | Variability in Tuberculosis Granuloma T Cell Responses Exists, but a Balance of Pro- and Anti-inflammatory Cytokines Is Associated with Sterilization | PLoS Pathogens | 2015 | 275 |
| 8 | Treatment of Acute Otitis Media in Children under 2 Years of Age | New England Journal of Medicine | 2011 | 252 |
| 9 | Use of dexmedetomidine in children after cardiac and thoracic surgery* | Pediatric Critical Care Medicine | 2006 | 182 |
| 10 | CD8 T cells and Mycobacterium tuberculosis infection | Seminars in Immunopathology | 2015 | 169 |
| 11 | Classical maple syrup urine disease and brain development: Principles of management and formula design | Molecular Genetics and Metabolism | 2010 | 157 |
| 12 | Liver Transplantation for Classical Maple Syrup Urine Disease: Long-Term Follow-Up in 37 Patients and Comparative United Network for Organ Sharing Experience | Journal of Pediatrics | 2012 | 154 |
| 13 | Digitally Barcoding Mycobacterium tuberculosis Reveals In Vivo Infection Dynamics in the Macaque Model of Tuberculosis | MBio | 2017 | 146 |
| 14 | CD4 T Cell Depletion Exacerbates AcuteMycobacterium tuberculosisWhile Reactivation of Latent Infection Is Dependent on Severity of Tissue Depletion in Cynomolgus Macaques | AIDS Research and Human Retroviruses | 2012 | 121 |
| 15 | PET/CT imaging reveals a therapeutic response to oxazolidinones in macaques and humans with tuberculosis | Science Translational Medicine | 2014 | 116 |
| 16 | FoxO6 Integrates Insulin Signaling With Gluconeogenesis in the Liver | Diabetes | 2011 | 113 |
| 17 | ATF4 Protein Deficiency Protects against High Fructose-induced Hypertriglyceridemia in Mice | Journal of Biological Chemistry | 2013 | 110 |
| 18 | Glycogen metabolism and glycogen storage disorders | Annals of Translational Medicine | 2018 | 104 |
| 19 | Interleukin-17 Contributes to Generation of Th1 Immunity and Neutrophil Recruitment duringChlamydia muridarumGenital Tract Infection but Is Not Required for Macrophage Influx or Normal Resolution of Infection | Infection and Immunity | 2011 | 103 |
| 20 | ADCYAP1R1 and Asthma in Puerto Rican Children | American Journal of Respiratory and Critical Care Medicine | 2013 | 97 |
| 21 | Helium/Oxygen-Driven Albuterol Nebulization in the Treatment of Children With Moderate to Severe Asthma Exacerbations: A Randomized, Controlled Trial | Pediatrics | 2005 | 94 |
| 22 | Serum S100B Concentrations Are Increased after Closed Head Injury in Children: A Preliminary Study | Journal of Neurotrauma | 2002 | 93 |
| 23 | Protein Arginine Methyltransferase 6 Enhances Polyglutamine-Expanded Androgen Receptor Function and Toxicity in Spinal and Bulbar Muscular Atrophy | Neuron | 2015 | 89 |
| 24 | Traumatic injury induces stress granule formation and enhances motor dysfunctions in ALS/FTD models | Human Molecular Genetics | 2018 | 86 |
| 25 | Early experience with the HeartMate 3 continuous-flow ventricular assist device in pediatric patients and patients with congenital heart disease: A multicenter registry analysis | Journal of Heart and Lung Transplantation | 2020 | 83 |
| 26 | Novel Advances in Understanding of Molecular Pathogenesis of Hepatoblastoma: A Wnt/β-Catenin Perspective | Gene Expression | 2017 | 82 |
| 27 | Liver transplantation in children with cystic fibrosis: a long-term longitudinal review of a single center’s experience | Journal of Pediatric Surgery | 2003 | 79 |
| 28 | Sterol metabolism disorders and neurodevelopment—an update | Developmental Disabilities Research Reviews | 2013 | 74 |
| 29 | Regulation of Reactive Oxygen Species Homeostasis by Peroxiredoxins and c-Myc | Journal of Biological Chemistry | 2009 | 73 |
| 30 | The chaperone HSPB8 reduces the accumulation of truncated TDP-43 species in cells and protects against TDP-43-mediated toxicity | Human Molecular Genetics | 2016 | 72 |
| 31 | Quinolinic Acid is Increased in CSF and Associated with Mortality after Traumatic Brain Injury in Humans | Journal of Cerebral Blood Flow and Metabolism | 1998 | 71 |
| 32 | Dexmedetomidine as the primary sedative during invasive procedures in infants and toddlers with congenital heart disease | Pediatric Critical Care Medicine | 2008 | 71 |
| 33 | Analysis of <sup>18</sup>FDG PET/CT Imaging as a Tool for Studying <em>Mycobacterium tuberculosis</em> Infection and Treatment in Non-human Primates | Journal of Visualized Experiments | 2017 | 71 |
| 34 | Review of methods for measuring β‐cell function: Design considerations from the Restoring Insulin Secretion (RISE) Consortium | Diabetes, Obesity and Metabolism | 2018 | 71 |
| 35 | Concurrent infection with Mycobacterium tuberculosis confers robust protection against secondary infection in macaques | PLoS Pathogens | 2018 | 69 |
| 36 | A computational tool integrating host immunity with antibiotic dynamics to study tuberculosis treatment | Journal of Theoretical Biology | 2015 | 68 |
| 37 | Lymph nodes are sites of prolonged bacterial persistence during Mycobacterium tuberculosis infection in macaques | PLoS Pathogens | 2018 | 67 |
| 38 | PLPHP deficiency: clinical, genetic, biochemical, and mechanistic insights | Brain | 2019 | 67 |
| 39 | Biliary atresia: A transplant perspective | Liver Transplantation | 2007 | 65 |
| 40 | Long-term, open-label extension study of the efficacy and safety of epicutaneous immunotherapy for peanut allergy in children: PEOPLE 3-year results | Journal of Allergy and Clinical Immunology | 2020 | 63 |
| 41 | Variants in Toll-like Receptor 1 and 4 Genes Are Associated With Chlamydia trachomatis Among Women With Pelvic Inflammatory Disease | Journal of Infectious Diseases | 2012 | 60 |
| 42 | PARVOVIRUS B19 INFECTION IN PEDIATRIC TRANSPLANT PATIENTS | Transplantation | 1993 | 58 |
| 43 | A Learning Collaborative Approach Increases Specificity of Diagnosis of Acute Liver Failure in Pediatric Patients | Clinical Gastroenterology and Hepatology | 2018 | 58 |
| 44 | Relationships among Obstructive Sleep Apnea, Anthropometric Measures, and Neurocognitive Functioning in Adolescents with Severe Obesity | Journal of Pediatrics | 2012 | 57 |
| 45 | Efficacy and Safety of Immunosuppression Withdrawal in Pediatric Liver Transplant Recipients: Moving Toward Personalized Management | Hepatology | 2021 | 57 |
| 46 | Pur-alpha regulates cytoplasmic stress granule dynamics and ameliorates FUS toxicity | Acta Neuropathologica | 2016 | 56 |
| 47 | Islet xenotransplantation: what is the optimal age of the islet‐source pig? | Xenotransplantation | 2015 | 55 |
| 48 | Phylogenetic Analysis of Polyomavirus BK Sequences | Journal of Virology | 2006 | 54 |
| 49 | Identifying Neurocognitive Deficits in Adolescents Following Concussion | Academic Emergency Medicine | 2011 | 54 |
| 50 | Interactions between ALS-linked FUS and nucleoporins are associated with defects in the nucleocytoplasmic transport pathway | Nature Neuroscience | 2021 | 54 |
