| # | Title | Journal | Year | Citations |
|---|
| 1 | The Loss of Skeletal Muscle Strength, Mass, and Quality in Older Adults: The Health, Aging and Body Composition Study | Journals of Gerontology - Series A Biological Sciences and Medical Sciences | 2006 | 2,216 |
| 2 | Acetaminophen-induced acute liver failure: Results of a United States multicenter, prospective study | Hepatology | 2005 | 1,688 |
| 3 | ACG Clinical Guideline: Genetic Testing and Management of Hereditary Gastrointestinal Cancer Syndromes | American Journal of Gastroenterology | 2015 | 1,204 |
| 4 | WFH Guidelines for the Management of Hemophilia, 3rd edition | Haemophilia | 2020 | 915 |
| 5 | High-Dose Interferon Alfa-2b Significantly Prolongs Relapse-Free and Overall Survival Compared With the GM2-KLH/QS-21 Vaccine in Patients With Resected Stage IIB-III Melanoma: Results of Intergroup Trial E1694/S9512/C509801 | Journal of Clinical Oncology | 2001 | 907 |
| 6 | Obesity, Regional Body Fat Distribution, and the Metabolic Syndrome in Older Men and Women | Archives of Internal Medicine | 2005 | 532 |
| 7 | Association Between Regional Adipose Tissue Distribution and Both Type 2 Diabetes and Impaired Glucose Tolerance in Elderly Men and Women | Diabetes Care | 2003 | 526 |
| 8 | A Pooled Analysis of Eastern Cooperative Oncology Group and Intergroup Trials of Adjuvant High-Dose Interferon for Melanoma | Clinical Cancer Research | 2004 | 510 |
| 9 | Bacteriophage targeting of gut bacterium attenuates alcoholic liver disease | Nature | 2019 | 493 |
| 10 | Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure | Nature Communications | 2020 | 466 |
| 11 | Improvement in Pulmonary Function and Elastic Recoil after Lung-Reduction Surgery for Diffuse Emphysema | New England Journal of Medicine | 1996 | 453 |
| 12 | The t(5;17) variant of acute promyelocytic leukemia expresses a nucleophosmin-retinoic acid receptor fusion | Blood | 1996 | 437 |
| 13 | Shared Genetic Predisposition in Peripartum and Dilated Cardiomyopathies | New England Journal of Medicine | 2016 | 432 |
| 14 | Interferon-γ Drives Treg Fragility to Promote Anti-tumor Immunity | Cell | 2017 | 431 |
| 15 | Comprehensive Invasive and Noninvasive Approach to the Right Ventricle–Pulmonary Circulation Unit | Circulation | 2009 | 429 |
| 16 | Heme oxygenase/carbon monoxide signaling pathways: regulation and functional significance | Molecular and Cellular Biochemistry | 2002 | 425 |
| 17 | Comparison of BISAP, Ranson's, APACHE-II, and CTSI Scores in Predicting Organ Failure, Complications, and Mortality in Acute Pancreatitis | American Journal of Gastroenterology | 2010 | 412 |
| 18 | Interstitial Lung Disease Associated With the Idiopathic Inflammatory Myopathies | Chest | 2010 | 366 |
| 19 | Continuous versus intermittent renal replacement therapy: a meta-analysis | Intensive Care Medicine | 2002 | 351 |
| 20 | Shared and distinct mechanisms of fibrosis | Nature Reviews Rheumatology | 2019 | 331 |
| 21 | Lipotoxicity Causes Multisystem Organ Failure and Exacerbates Acute Pancreatitis in Obesity | Science Translational Medicine | 2011 | 328 |
| 22 | Effect and Safety of Meropenem–Vaborbactam versus Best-Available Therapy in Patients with Carbapenem-Resistant Enterobacteriaceae Infections: The TANGO II Randomized Clinical Trial | Infectious Diseases and Therapy | 2018 | 313 |
| 23 | Severe Community-acquired Pneumonia | American Journal of Respiratory and Critical Care Medicine | 2002 | 307 |
| 24 | Elevated TNF-alpha production by peripheral blood monocytes of weight-losing COPD patients. | American Journal of Respiratory and Critical Care Medicine | 1996 | 302 |
| 25 | Paget disease of bone | Journal of Clinical Investigation | 2005 | 295 |
| 26 | The Cost of Inflammatory Bowel Disease: An Initiative From the Crohn’s & Colitis Foundation | Inflammatory Bowel Diseases | 2020 | 274 |
| 27 | Hyperkalemia in Hospitalized Patients | Archives of Internal Medicine | 1998 | 273 |
| 28 | Influenza and Bacterial Superinfection: Illuminating the Immunologic Mechanisms of Disease | Infection and Immunity | 2015 | 254 |
| 29 | Esophagectomy for T1 Esophageal Cancer: Outcomes in 100 Patients and Implications for Endoscopic Therapy | Annals of Thoracic Surgery | 2009 | 242 |
| 30 | Bone Formation in Carotid Plaques | Stroke | 2002 | 239 |
| 31 | Tumor-Stroma Mechanics Coordinate Amino Acid Availability to Sustain Tumor Growth and Malignancy | Cell Metabolism | 2019 | 232 |
| 32 | Distribution of Brain HIV Load in AIDS | Brain Pathology | 1998 | 231 |
| 33 | Control of an Outbreak of Infection with the Hypervirulent Clostridium difficile BI Strain in a University Hospital Using a Comprehensive "Bundle" Approach | Clinical Infectious Diseases | 2007 | 224 |
| 34 | Ceftolozane-Tazobactam for the Treatment of Multidrug-Resistant Pseudomonas aeruginosa Infections: Clinical Effectiveness and Evolution of Resistance | Clinical Infectious Diseases | 2017 | 224 |
| 35 | Biological Chemistry of Thiols in the Vasculature and in Vascular-related Disease | Nutrition Reviews | 1996 | 218 |
| 36 | ctDNA applications and integration in colorectal cancer: an NCI Colon and Rectal–Anal Task Forces whitepaper | Nature Reviews Clinical Oncology | 2020 | 218 |
| 37 | Body Fat Distribution and Inflammation Among Obese Older Adults With and Without Metabolic Syndrome | Obesity | 2010 | 217 |
| 38 | Influenza Virus Infection in Adult Solid Organ Transplant Recipients | American Journal of Transplantation | 2002 | 212 |
| 39 | Estrogen-induced cardiorenal protection: potential cellular, biochemical, and molecular mechanisms | American Journal of Physiology - Renal Physiology | 2001 | 208 |
| 40 | Does the Amount of Fat Mass Predict Age-Related Loss of Lean Mass, Muscle Strength, and Muscle Quality in Older Adults? | Journals of Gerontology - Series A Biological Sciences and Medical Sciences | 2011 | 205 |
| 41 | Epigenetic side-effects of common pharmaceuticals: A potential new field in medicine and pharmacology | Medical Hypotheses | 2009 | 202 |
| 42 | Inflammation and Race and Gender Differences in Computerized Tomography‐measured Adipose Depots | Obesity | 2009 | 200 |
| 43 | Use of Multilocus Variable Number of Tandem Repeats Analysis Genotyping to Determine the Role of Asymptomatic Carriers in Clostridium difficile Transmission | Clinical Infectious Diseases | 2013 | 197 |
| 44 | Pseudallescheria boydii (Anamorph Scedosporium apiospermum) Infection in Solid Organ Transplant Recipients in a Tertiary Medical Center and Review of the Literature | Medicine (United States) | 2002 | 196 |
| 45 | Impact of Human Immunodeficiency Virus Infection on Progression to End‐Stage Liver Disease in Individuals with Hemophilia and Hepatitis C Virus Infection | Journal of Infectious Diseases | 2001 | 193 |
| 46 | Elevated Serum Triglycerides are Independently Associated With Persistent Organ Failure in Acute Pancreatitis | American Journal of Gastroenterology | 2015 | 193 |
| 47 | Bacteria in the bloodstream are trapped in the liver and killed by immigrating neutrophils. | Journal of Immunology | 1996 | 181 |
| 48 | tcdC Genotypes Associated with Severe TcdC Truncation in an Epidemic Clone and Other Strains of Clostridium difficile | Journal of Clinical Microbiology | 2007 | 177 |
| 49 | Evaluation of Mavacamten in Symptomatic Patients With Nonobstructive Hypertrophic Cardiomyopathy | Journal of the American College of Cardiology | 2020 | 176 |
| 50 | Matrix Metalloproteinase 3 Is a Mediator of Pulmonary Fibrosis | American Journal of Pathology | 2011 | 174 |
