| # | Title | Journal | Year | Citations |
|---|
| 1 | The Physiology of Glucagon-like Peptide 1 | Physiological Reviews | 2007 | 2,504 |
| 2 | Effect of 6-week course of glucagon-like peptide 1 on glycaemic control, insulin sensitivity, and β-cell function in type 2 diabetes: a parallel-group study | Lancet, The | 2002 | 1,207 |
| 3 | Uncovering Molecular Mechanisms Involved in Activation of G Protein-Coupled Receptors | Endocrine Reviews | 2000 | 1,114 |
| 4 | Inhibition of gastric inhibitory polypeptide signaling prevents obesity | Nature Medicine | 2002 | 798 |
| 5 | Both Subcutaneously and Intravenously Administered Glucagon-Like Peptide I Are Rapidly Degraded From the NH2-Terminus in Type II Diabetic Patients and in Healthy Subjects | Diabetes | 1995 | 721 |
| 6 | Degradation of glucagon-like peptide-1 by human plasma in vitro yields an N-terminally truncated peptide that is a major endogenous metabolite in vivo. | Journal of Clinical Endocrinology and Metabolism | 1995 | 629 |
| 7 | From MDR to MXR: new understanding of multidrug resistance systems, their properties and clinical significance | Cellular and Molecular Life Sciences | 2001 | 591 |
| 8 | Distribution of glucagon-like peptide-1 and other preproglucagon-derived peptides in the rat hypothalamus and brainstem | Neuroscience | 1997 | 548 |
| 9 | Role of incretin hormones in the regulation of insulin secretion in diabetic and nondiabetic humans | American Journal of Physiology - Endocrinology and Metabolism | 2004 | 518 |
| 10 | The Influence of GLP-1 on Glucose-Stimulated Insulin Secretion: Effects on -Cell Sensitivity in Type 2 and Nondiabetic Subjects | Diabetes | 2003 | 513 |
| 11 | Strength Training Increases Insulin-Mediated Glucose Uptake, GLUT4 Content, and Insulin Signaling in Skeletal Muscle in Patients With Type 2 Diabetes | Diabetes | 2004 | 498 |
| 12 | Glucagon-Like Peptide-1-(7–36)Amide Is Transformed to Glucagon-Like Peptide-1-(9–36)Amide by Dipeptidyl Peptidase IV in the Capillaries Supplying the L Cells of the Porcine Intestine1 | Endocrinology | 1999 | 497 |
| 13 | Inhibition of the activity of dipeptidyl-peptidase IV as a treatment for type 2 diabetes | Diabetes | 1998 | 496 |
| 14 | Distribution of Networks Generating and Coordinating Locomotor Activity in the Neonatal Rat Spinal CordIn Vitro: A Lesion Study | Journal of Neuroscience | 1996 | 481 |
| 15 | PDGF-BB induces intratumoral lymphangiogenesis and promotes lymphatic metastasis | Cancer Cell | 2004 | 480 |
| 16 | A Meta-Analysis of the Effect of Glucagon-Like Peptide-1 (7–36) Amide on Ad Libitum Energy Intake in Humans | Journal of Clinical Endocrinology and Metabolism | 2001 | 468 |
| 17 | Secretion of glucagon-like peptide-1 (GLP-1) in type 2 diabetes: what is up, what is down? | Diabetologia | 2011 | 402 |
| 18 | Motor skill training induces changes in the excitability of the leg cortical area in healthy humans | Experimental Brain Research | 2004 | 396 |
| 19 | On the mechanism of the post-activation depression of the H-reflex in human subjects | Experimental Brain Research | 1996 | 385 |
| 20 | Energy intake and appetite are suppressed by glucagon-like peptide-1 (GLP-1) in obese men. | International Journal of Obesity | 1999 | 384 |
| 21 | Incretins, insulin secretion and Type 2 diabetes mellitus | Diabetologia | 2004 | 371 |
| 22 | Both GLP-1 and GIP are insulinotropic at basal and postprandial glucose levels and contribute nearly equally to the incretin effect of a meal in healthy subjects | Regulatory Peptides | 2003 | 360 |
| 23 | The role of postprandial releases of insulin and incretin hormones in meal-induced satiety—effect of obesity and weight reduction | International Journal of Obesity | 2001 | 353 |
| 24 | Severe hypoglycaemia post-gastric bypass requiring partial pancreatectomy: evidence for inappropriate insulin secretion and pancreatic islet hyperplasia | Diabetologia | 2005 | 345 |
| 25 | Degradation of Endogenous and Exogenous Gastric Inhibitory Polypeptide in Healthy and in Type 2 Diabetic Subjects as Revealed Using a New Assay for the Intact Peptide1 | Journal of Clinical Endocrinology and Metabolism | 2000 | 344 |
| 26 | Summary of the Recommendations on Sexual Dysfunctions in Men | Journal of Sexual Medicine | 2004 | 334 |
| 27 | The spinal pathophysiology of spasticity ? from a basic science point of view | Acta Physiologica | 2007 | 328 |
| 28 | Modification of activity-dependent increases of cerebral blood flow by excitatory synaptic activity and spikes in rat cerebellar cortex | Journal of Physiology | 1998 | 327 |
| 29 | Motor skill training and strength training are associated with different plastic changes in the central nervous system | Journal of Applied Physiology | 2005 | 322 |
| 30 | Spatiotemporal characteristics of 5-HT and dopamine-induced rhythmic hindlimb activity in the in vitro neonatal rat | Journal of Neurophysiology | 1996 | 318 |
| 31 | Exaggerated glucagon-like peptide-1 and blunted glucose-dependent insulinotropic peptide secretion are associated with Roux-en-Y gastric bypass but not adjustable gastric banding | Surgery for Obesity and Related Diseases | 2007 | 311 |
| 32 | Predictors of Incretin Concentrations in Subjects With Normal, Impaired, and Diabetic Glucose Tolerance | Diabetes | 2008 | 307 |
| 33 | Dipeptidyl peptidase IV inhibition potentiates the insulinotropic effect of glucagon-like peptide 1 in the anesthetized pig | Diabetes | 1998 | 304 |
| 34 | The effect of physiological levels of glucagon-like peptide-1 on appetite, gastric emptying, energy and substrate metabolism in obesity | International Journal of Obesity | 2001 | 299 |
| 35 | Aquaporin homologues in plants and mammals transport ammonia | FEBS Letters | 2004 | 297 |
| 36 | Reduced Incretin Effect in Type 2 Diabetes | Diabetes | 2007 | 297 |
| 37 | Rapid Tachyphylaxis of the Glucagon-Like Peptide 1–Induced Deceleration of Gastric Emptying in Humans | Diabetes | 2011 | 291 |
| 38 | ENTEROGLUCAGON | Annual Review of Physiology | 1997 | 287 |
| 39 | Somatostatin receptors | Biochimica Et Biophysica Acta - Biomembranes | 2003 | 284 |
| 40 | GLP-1 and GIP are colocalized in a subset of endocrine cells in the small intestine | Regulatory Peptides | 2003 | 284 |
| 41 | Impaired glucagon-like peptide-1-induced insulin secretion in carriers of transcription factor 7-like 2 (TCF7L2) gene polymorphisms | Diabetologia | 2007 | 284 |
| 42 | Secretion, Degradation, and Elimination of Glucagon-Like Peptide 1 and Gastric Inhibitory Polypeptide in Patients with Chronic Renal Insufficiency and Healthy Control Subjects | Diabetes | 2004 | 277 |
| 43 | Dipeptidyl peptidase IV resistant analogues of glucagon-like peptide-1 which have extended metabolic stability and improved biological activity | Diabetologia | 1998 | 273 |
| 44 | Role of Gastrointestinal Hormones in Postprandial Reduction of Bone Resorption | Journal of Bone and Mineral Research | 2003 | 272 |
| 45 | Gastric inhibitory polypeptide (GIP) dose-dependently stimulates glucagon secretion in healthy human subjects at euglycaemia | Diabetologia | 2003 | 270 |
| 46 | Aquaporins in complex tissues: distribution of aquaporins 1–5 in human and rat eye | American Journal of Physiology - Cell Physiology | 1998 | 262 |
| 47 | Spasticity-assessment: a review | Spinal Cord | 2006 | 259 |
| 48 | Major role for sensory feedback in soleus EMG activity in the stance phase of walking in man | Journal of Physiology | 2000 | 257 |
| 49 | The Cephalic Insulin Response to Meal Ingestion in Humans Is Dependent on Both Cholinergic and Noncholinergic Mechanisms and Is Important for Postprandial Glycemia | Diabetes | 2001 | 255 |
| 50 | Glucagon-like peptide-1 mediates the therapeutic actions of DPP-IV inhibitors | Diabetologia | 2005 | 250 |
