# | Title | Journal | Year | Citations |
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1 | Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines | Journal of Extracellular Vesicles | 2018 | 6,961 |
2 | Guidelines for the use and interpretation of assays for monitoring autophagy | Autophagy | 2012 | 3,122 |
3 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
4 | A call for transparent reporting to optimize the predictive value of preclinical research | Nature | 2012 | 1,055 |
5 | Role of Tyrosine Kinase Inhibitors in Cancer Therapy | Journal of Pharmacology and Experimental Therapeutics | 2005 | 846 |
6 | Diagnostics for SARS-CoV-2 infections | Nature Materials | 2021 | 533 |
7 | The sigma-1 receptor chaperone as an inter-organelle signaling modulator | Trends in Pharmacological Sciences | 2010 | 394 |
8 | The Natural History, Pathobiology, and Clinical Manifestations of SARS-CoV-2 Infections | Journal of NeuroImmune Pharmacology | 2020 | 391 |
9 | Oxidative Stress and the Pathogenesis of Neurodegenerative Disorders | International Review of Neurobiology | 2007 | 350 |
10 | Interferon-γ and Tumor Necrosis Factor-α Regulate Amyloid-β Plaque Deposition and β-Secretase Expression in Swedish Mutant APP Transgenic Mice | American Journal of Pathology | 2007 | 348 |
11 | Regulatory T Cells Attenuate Th17 Cell-Mediated Nigrostriatal Dopaminergic Neurodegeneration in a Model of Parkinson’s Disease | Journal of Immunology | 2010 | 346 |
12 | Interactions of Oxidative Stress and Neurovascular Inflammation in the Pathogenesis of Traumatic Brain Injury | Molecular Neurobiology | 2015 | 333 |
13 | Neuroprotective activities of CD4+CD25+ regulatory T cells in an animal model of Parkinson’s disease | Journal of Leukocyte Biology | 2007 | 323 |
14 | Nitrated α–Synuclein Immunity Accelerates Degeneration of Nigral Dopaminergic Neurons | PLoS ONE | 2008 | 311 |
15 | Neuroinflammation, oxidative stress, and the pathogenesis of Parkinson’s disease | Clinical Neuroscience Research | 2006 | 305 |
16 | Oxidative stress activates protein tyrosine kinase and matrix metalloproteinases leading to blood?brain barrier dysfunction | Journal of Neurochemistry | 2007 | 295 |
17 | Mechanism of alcohol-induced oxidative stress and neuronal injury | Free Radical Biology and Medicine | 2008 | 285 |
18 | Inflammatory cell infiltration of tumors: Jekyll or Hyde | Cancer and Metastasis Reviews | 2007 | 283 |
19 | IL‐1β and TNF‐α induce neurotoxicity through glutamate production: a potential role for neuronal glutaminase | Journal of Neurochemistry | 2013 | 271 |
20 | CD4+ Regulatory and Effector/Memory T Cell Subsets Profile Motor Dysfunction in Parkinson’s Disease | Journal of NeuroImmune Pharmacology | 2012 | 255 |
21 | Tight Junction Proteins and Signaling Pathways in Cancer and Inflammation: A Functional Crosstalk | Frontiers in Physiology | 2018 | 252 |
22 | Development of a macrophage-based nanoparticle platform for antiretroviral drug delivery | Blood | 2006 | 241 |
23 | Alcohol-induced oxidative stress in brain endothelial cells causes blood-brain barrier dysfunction | Journal of Leukocyte Biology | 2005 | 240 |
24 | Methylome-wide Analysis of Chronic HIV Infection Reveals Five-Year Increase in Biological Age and Epigenetic Targeting of HLA | Molecular Cell | 2016 | 233 |
25 | Induction of oxidative and nitrosative damage leads to cerebrovascular inflammation in an animal model of mild traumatic brain injury induced by primary blast | Free Radical Biology and Medicine | 2013 | 224 |
26 | Sequential LASER ART and CRISPR Treatments Eliminate HIV-1 in a Subset of Infected Humanized Mice | Nature Communications | 2019 | 222 |
27 | Inflammation and Adaptive Immunity in Parkinson's Disease | Cold Spring Harbor Perspectives in Medicine | 2012 | 221 |
28 | Macrophage Delivery of Nanoformulated Antiretroviral Drug to the Brain in a Murine Model of NeuroAIDS | Journal of Immunology | 2009 | 211 |
29 | Interplay of endoplasmic reticulum stress and autophagy in neurodegenerative disorders | Autophagy | 2016 | 207 |
30 | Phosphorylation of Claudin-5 and Occludin by Rho Kinase in Brain Endothelial Cells | American Journal of Pathology | 2008 | 204 |
31 | Methamphetamine-Associated Psychosis | Journal of NeuroImmune Pharmacology | 2012 | 202 |
32 | A Functional Transsulfuration Pathway in the Brain Links to Glutathione Homeostasis | Journal of Biological Chemistry | 2006 | 198 |
33 | Biochemical and Biologic Characterization of Exosomes and Microvesicles as Facilitators of HIV-1 Infection in Macrophages | Journal of Immunology | 2012 | 198 |
34 | Adaptive immunity affects learning behavior in mice | Brain, Behavior, and Immunity | 2008 | 191 |
35 | Nitrated α-Synuclein-Induced Alterations in Microglial Immunity Are Regulated by CD4+ T Cell Subsets | Journal of Immunology | 2009 | 177 |
36 | Adaptive Immune Neuroprotection in G93A-SOD1 Amyotrophic Lateral Sclerosis Mice | PLoS ONE | 2008 | 174 |
37 | Brain-derived neurotrophic factor and its receptor tropomyosin-related kinase B in the mechanism of action of antidepressant therapies | PLoS ONE | 2008 | 173 |
38 | Toll-like receptor (TLR) and inflammasome actions in the central nervous system | Trends in Immunology | 2012 | 173 |
39 | Exosome-mediated shuttling of microRNA-29 regulates HIV Tat and morphine-mediated Neuronal dysfunction | Cell Death and Disease | 2012 | 172 |
40 | Excision of HIV-1 DNA by gene editing: a proof-of-concept in vivo study | Gene Therapy | 2016 | 167 |
41 | A new rhesus macaque assembly and annotation for next-generation sequencing analyses | Biology Direct | 2014 | 165 |
42 | The National NeuroAIDS Tissue Consortium Brain Gene Array: Two Types of HIV-Associated Neurocognitive Impairment | PLoS ONE | 2012 | 150 |
43 | HIV-1 Tat Primes and Activates Microglial NLRP3 Inflammasome-Mediated Neuroinflammation | Journal of Neuroscience | 2017 | 145 |
44 | Molecular mechanisms of long noncoding RNAs and their role in disease pathogenesis | Oncotarget | 2018 | 144 |
45 | Effects of pluronic and doxorubicin on drug uptake, cellular metabolism, apoptosis and tumor inhibition in animal models of MDR cancers | Journal of Controlled Release | 2010 | 142 |
46 | Stride-time variability and sensorimotor cortical activation during walking | NeuroImage | 2012 | 136 |
47 | MiR-9 promotes microglial activation by targeting MCPIP1 | Nature Communications | 2014 | 133 |
48 | STAT1 signaling modulates HIV-1–induced inflammatory responses and leukocyte transmigration across the blood-brain barrier | Blood | 2008 | 130 |
49 | Inflammasome activation and IL‐1β/IL‐18 processing are influenced by distinct pathways in microglia | Journal of Neurochemistry | 2011 | 127 |
50 | Traumatic brain injury increases levels of miR‐21 in extracellular vesicles: implications for neuroinflammation | FEBS Open Bio | 2016 | 127 |