| # | Title | Journal | Year | Citations |
|---|
| 1 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 2 | Management of Adults With Hospital-acquired and Ventilator-associated Pneumonia: 2016 Clinical Practice Guidelines by the Infectious Diseases Society of America and the American Thoracic Society | Clinical Infectious Diseases | 2016 | 2,405 |
| 3 | Guidelines for the Prevention of Intravascular Catheter-related Infections | Clinical Infectious Diseases | 2011 | 2,242 |
| 4 | New approach to classifying non-Hodgkin's lymphomas: clinical features of the major histologic subtypes. Non-Hodgkin's Lymphoma Classification Project. | Journal of Clinical Oncology | 1998 | 1,119 |
| 5 | Molecular Diagnosis of Primary Mediastinal B Cell Lymphoma Identifies a Clinically Favorable Subgroup of Diffuse Large B Cell Lymphoma Related to Hodgkin Lymphoma | Journal of Experimental Medicine | 2003 | 1,002 |
| 6 | The proliferation gene expression signature is a quantitative integrator of oncogenic events that predicts survival in mantle cell lymphoma | Cancer Cell | 2003 | 848 |
| 7 | A Genetic Resource for Rapid and Comprehensive Phenotype Screening of Nonessential Staphylococcus aureus Genes | MBio | 2013 | 718 |
| 8 | A Genome-Wide Association Study in Chronic Obstructive Pulmonary Disease (COPD): Identification of Two Major Susceptibility Loci | PLoS Genetics | 2009 | 656 |
| 9 | Bone Marrow Transplantation | New England Journal of Medicine | 1994 | 624 |
| 10 | Treatment of Rheumatoid Arthritis with Methotrexate Alone, Sulfasalazine and Hydroxychloroquine, or a Combination of All Three Medications | New England Journal of Medicine | 1996 | 566 |
| 11 | Therapeutic Strategies for Rheumatoid Arthritis | New England Journal of Medicine | 2004 | 489 |
| 12 | Hepatocellular carcinoma | Lancet, The | 1999 | 487 |
| 13 | A susceptibility locus for Parkinson's disease maps to chromosome 2p13 | Nature Genetics | 1998 | 486 |
| 14 | Ceftriaxone-Resistant Salmonella Infection Acquired by a Child from Cattle | New England Journal of Medicine | 2000 | 481 |
| 15 | Coagulase-Negative Staphylococci: Pathogens Associated with Medical Progress | Clinical Infectious Diseases | 1994 | 462 |
| 16 | Effectiveness and Safety of the Awakening and Breathing Coordination, Delirium Monitoring/Management, and Early Exercise/Mobility Bundle* | Critical Care Medicine | 2014 | 442 |
| 17 | Clinical esophageal pH recording: A technical review for practice guideline development | Gastroenterology | 1996 | 439 |
| 18 | Summary of Recommendations: Guidelines for the Prevention of Intravascular Catheter-related Infections | Clinical Infectious Diseases | 2011 | 407 |
| 19 | Treating COVID-19—Off-Label Drug Use, Compassionate Use, and Randomized Clinical Trials During Pandemics | JAMA - Journal of the American Medical Association | 2020 | 396 |
| 20 | Autologous peripheral hematopoietic stem cell transplantation restores hematopoietic function following marrow ablative therapy | Blood | 1988 | 378 |
| 21 | Cigarette smoke induces interleukin-8 release from human bronchial epithelial cells. | American Journal of Respiratory and Critical Care Medicine | 1997 | 378 |
| 22 | Peripheral T-cell lymphoma, not otherwise specified: a report of 340 cases from the International Peripheral T-cell Lymphoma Project | Blood | 2011 | 376 |
| 23 | MUC1 and HIF-1alpha Signaling Crosstalk Induces Anabolic Glucose Metabolism to Impart Gemcitabine Resistance to Pancreatic Cancer | Cancer Cell | 2017 | 373 |
| 24 | Modulation of Airway Epithelial Cell Ciliary Beat Frequency by Nitric Oxide | Biochemical and Biophysical Research Communications | 1993 | 363 |
| 25 | Treatment of Non-Hodgkin's Lymphoma | New England Journal of Medicine | 1993 | 363 |
| 26 | Gastrointestinal dysfunction in Parkinson's disease | Neurology | 1992 | 345 |
| 27 | Intraluminal Airway Inflammation in Chronic Bronchitis: Characterization and Correlation with Clinical Parameters | The American Review of Respiratory Disease | 1989 | 342 |
| 28 | Executive Summary: Management of Adults With Hospital-acquired and Ventilator-associated Pneumonia: 2016 Clinical Practice Guidelines by the Infectious Diseases Society of America and the American Thoracic Society | Clinical Infectious Diseases | 2016 | 334 |
| 29 | Hepatobiliary complications of total parenteral nutrition | Gastroenterology | 1993 | 333 |
| 30 | Dopaminergic defect of enteric nervous system in Parkinson's disease patients with chronic constipation | Lancet, The | 1995 | 331 |
| 31 | Incidence and characterization of secondary myelodysplastic syndrome and acute myelogenous leukemia following high-dose chemoradiotherapy and autologous stem-cell transplantation for lymphoid malignancies. | Journal of Clinical Oncology | 1994 | 314 |
| 32 | Nitrated α–Synuclein Immunity Accelerates Degeneration of Nigral Dopaminergic Neurons | PLoS ONE | 2008 | 311 |
| 33 | Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis | Nature Genetics | 2017 | 306 |
| 34 | Increased cardiovascular risk in rheumatoid arthritis: mechanisms and implications | BMJ: British Medical Journal | 2018 | 303 |
| 35 | Comparative Molecular Analysis of Community- or Hospital-Acquired Methicillin-Resistant Staphylococcus aureus | Antimicrobial Agents and Chemotherapy | 2003 | 301 |
| 36 | Extended Spectrum ??-Lactamase (ESBL)-Producing Enterobacteriaceae | Drugs | 2003 | 293 |
| 37 | Influenza virus-related critical illness: pathophysiology and epidemiology | Critical Care | 2019 | 286 |
| 38 | Relationship of carbohydrate antigen 19-9 and Lewis antigens in pancreatic cancer | Cancer Research | 1987 | 282 |
| 39 | Emerging Applications of Recombinant Human Granulocyte-Macrophage Colony-Stimulating Factor | Blood | 1998 | 279 |
| 40 | Radiochemotherapy and Transplantation Allow Long-Term Survival For Nonresectable Hilar Cholangiocarcinoma | American Journal of Transplantation | 2002 | 270 |
| 41 | The importance of age in survival of patients treated with chemotherapy for aggressive non-Hodgkin's lymphoma. | Journal of Clinical Oncology | 1988 | 265 |
| 42 | Alcohol Metabolism-mediated Oxidative Stress Down-regulates Hepcidin Transcription and Leads to Increased Duodenal Iron Transporter Expression | Journal of Biological Chemistry | 2006 | 265 |
| 43 | Characterization of the Importance of Polysaccharide Intercellular Adhesin/Hemagglutinin of Staphylococcus epidermidis in the Pathogenesis of Biomaterial-Based Infection in a Mouse Foreign Body Infection Model | Infection and Immunity | 1999 | 265 |
| 44 | Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations | Nature Genetics | 2019 | 257 |
| 45 | All-digital image capture and whole-field analysis of ciliary beat frequency | Journal of Microscopy | 2003 | 253 |
| 46 | State-of-the-Art Review of 3D Bioprinting for Cardiovascular Tissue Engineering | Annals of Biomedical Engineering | 2017 | 242 |
| 47 | High-dose therapy and autologous peripheral blood stem cell transplantation for patients with lymphoma | Blood | 1989 | 234 |
| 48 | Aprotinin and methylprednisolone equally blunt cardiopulmonary bypass–induced inflammation in humans | Journal of Thoracic and Cardiovascular Surgery | 1995 | 233 |
| 49 | Methylome-wide Analysis of Chronic HIV Infection Reveals Five-Year Increase in Biological Age and Epigenetic Targeting of HLA | Molecular Cell | 2016 | 233 |
| 50 | Standardisation of nailfold capillaroscopy for the assessment of patients with Raynaud's phenomenon and systemic sclerosis | Autoimmunity Reviews | 2020 | 231 |
