| # | Title | Journal | Year | Citations |
|---|
| 1 | Biological, clinical and population relevance of 95 loci for blood lipids | Nature | 2010 | 3,249 |
| 2 | Hundreds of variants clustered in genomic loci and biological pathways affect human height | Nature | 2010 | 1,789 |
| 3 | Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program | Nature | 2021 | 1,069 |
| 4 | The Metabolic Syndrome and 11-Year Risk of Incident Cardiovascular Disease in the Atherosclerosis Risk in Communities Study | Diabetes Care | 2005 | 988 |
| 5 | The genetic architecture of type 2 diabetes | Nature | 2016 | 952 |
| 6 | Carotid Intima-Media Thickness and Presence or Absence of Plaque Improves Prediction of Coronary Heart Disease Risk | Journal of the American College of Cardiology | 2010 | 794 |
| 7 | Diagnostic Yield and Clinical Utility of Sequencing Familial Hypercholesterolemia Genes in Patients With Severe Hypercholesterolemia | Journal of the American College of Cardiology | 2016 | 723 |
| 8 | Temporal Trends in Survival Among Infants With Critical Congenital Heart Defects | Pediatrics | 2013 | 521 |
| 9 | Genetic Structure, Self-Identified Race/Ethnicity, and Confounding in Case-Control Association Studies | American Journal of Human Genetics | 2005 | 513 |
| 10 | Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function | Nature Communications | 2018 | 484 |
| 11 | Association Between Midlife Vascular Risk Factors and Estimated Brain Amyloid Deposition | JAMA - Journal of the American Medical Association | 2017 | 451 |
| 12 | Common variants in KCNN3 are associated with lone atrial fibrillation | Nature Genetics | 2010 | 438 |
| 13 | Novel Loci for Adiponectin Levels and Their Influence on Type 2 Diabetes and Metabolic Traits: A Multi-Ethnic Meta-Analysis of 45,891 Individuals | PLoS Genetics | 2012 | 419 |
| 14 | Associations Between Midlife Vascular Risk Factors and 25-Year Incident Dementia in the Atherosclerosis Risk in Communities (ARIC) Cohort | JAMA Neurology | 2017 | 404 |
| 15 | Associations of serum and dietary magnesium with cardiovascular disease, hypertension, diabetes, insulin, and carotid arterial wall thickness: The aric study | Journal of Clinical Epidemiology | 1995 | 383 |
| 16 | Economic impact of heart failure in the United States: time for a different approach | Journal of Heart and Lung Transplantation | 1994 | 379 |
| 17 | Midlife Hypertension and 20-Year Cognitive Change | JAMA Neurology | 2014 | 358 |
| 18 | Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations | Cell | 2020 | 353 |
| 19 | The power of genetic diversity in genome-wide association studies of lipids | Nature | 2021 | 353 |
| 20 | Genetic contributions to variation in general cognitive function: a meta-analysis of genome-wide association studies in the CHARGE consortium (N=53 949) | Molecular Psychiatry | 2015 | 344 |
| 21 | The trans-ancestral genomic architecture of glycemic traits | Nature Genetics | 2021 | 341 |
| 22 | Reduced Neutrophil Count in People of African Descent Is Due To a Regulatory Variant in the Duffy Antigen Receptor for Chemokines Gene | PLoS Genetics | 2009 | 335 |
| 23 | The vasoprotective axes of the renin-angiotensin system: Physiological relevance and therapeutic implications in cardiovascular, hypertensive and kidney diseases | Pharmacological Research | 2017 | 332 |
| 24 | Titration of Medical Therapy for Heart Failure With Reduced Ejection Fraction | Journal of the American College of Cardiology | 2019 | 327 |
| 25 | Meta-analysis of Correlated Traits via Summary Statistics from GWASs with an Application in Hypertension | American Journal of Human Genetics | 2015 | 321 |
| 26 | The landscape of recombination in African Americans | Nature | 2011 | 319 |
| 27 | Association of Low-Frequency and Rare Coding-Sequence Variants with Blood Lipids and Coronary Heart Disease in 56,000 Whites and Blacks | American Journal of Human Genetics | 2014 | 287 |
| 28 | Novel genetic loci associated with hippocampal volume | Nature Communications | 2017 | 250 |
| 29 | Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls | Nature | 2019 | 248 |
| 30 | Population Structure in Admixed Populations: Effect of Admixture Dynamics on the Pattern of Linkage Disequilibrium | American Journal of Human Genetics | 2001 | 240 |
| 31 | Large-Scale Gene-Centric Meta-Analysis across 39 Studies Identifies Type 2 Diabetes Loci | American Journal of Human Genetics | 2012 | 239 |
| 32 | Associations of Dietary Cholesterol or Egg Consumption With Incident Cardiovascular Disease and Mortality | JAMA - Journal of the American Medical Association | 2019 | 238 |
| 33 | A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry | Nature Genetics | 2013 | 232 |
| 34 | The Multifaceted Mineralocorticoid Receptor | | 2014 | 231 |
| 35 | Stress, coping, and well-being among third-year medical students | Academic Medicine | 1994 | 228 |
| 36 | Large-Scale Gene-Centric Meta-analysis across 32 Studies Identifies Multiple Lipid Loci | American Journal of Human Genetics | 2012 | 227 |
| 37 | Association of Midlife to Late-Life Blood Pressure Patterns With Incident Dementia | JAMA - Journal of the American Medical Association | 2019 | 227 |
| 38 | Meta-analysis identifies common and rare variants influencing blood pressure and overlapping with metabolic trait loci | Nature Genetics | 2016 | 223 |
| 39 | Racial Differences in the Survival of Cadaveric Renal Allografts | New England Journal of Medicine | 1992 | 221 |
| 40 | Extra-adrenal glucocorticoids and mineralocorticoids: evidence for local synthesis, regulation, and function | American Journal of Physiology - Endocrinology and Metabolism | 2011 | 219 |
| 41 | Best Practices and Joint Calling of the HumanExome BeadChip: The CHARGE Consortium | PLoS ONE | 2013 | 219 |
| 42 | Measuring Blood Pressure Accurately | JAMA - Journal of the American Medical Association | 2003 | 214 |
| 43 | Novel genetic loci underlying human intracranial volume identified through genome-wide association | Nature Neuroscience | 2016 | 213 |
| 44 | Cold ischemia and the reduced long-term survival of cadaveric renal allografts | Kidney International | 2004 | 210 |
| 45 | Mild cognitive impairment and dementia prevalence: The Atherosclerosis Risk in Communities Neurocognitive Study | Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring | 2016 | 209 |
| 46 | Impaired local intrinsic immunity to SARS-CoV-2 infection in severe COVID-19 | Cell | 2021 | 206 |
| 47 | Trends in prehospital delay time and use of emergency medical services for acute myocardial infarction: Experience in 4 US communities from 1987-2000 | American Heart Journal | 2005 | 204 |
| 48 | The effect of chronic renal failure on drug metabolism and transport | Expert Opinion on Drug Metabolism and Toxicology | 2008 | 200 |
| 49 | Fourteen‐year longitudinal study of vascular risk factors, APOE genotype, and cognition: The ARIC MRI Study | Alzheimer's and Dementia | 2009 | 199 |
| 50 | Whole-Exome Sequencing Identifies Rare and Low-Frequency Coding Variants Associated with LDL Cholesterol | American Journal of Human Genetics | 2014 | 193 |
