# | Title | Journal | Year | Citations |
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1 | Angiotensin-Converting Enzyme 2 Suppresses Pathological Hypertrophy, Myocardial Fibrosis, and Cardiac Dysfunction | Circulation | 2010 | 383 |
2 | Benefits and harms of antidiabetic agents in patients with diabetes and heart failure: systematic review | BMJ: British Medical Journal | 2007 | 293 |
3 | Angiotensin Converting Enzyme 2 | Circulation | 2020 | 220 |
4 | Cardiac regulation by phosphoinositide 3-kinases and PTEN | Cardiovascular Research | 2008 | 218 |
5 | Iron-Overload Cardiomyopathy: Pathophysiology, Diagnosis, and Treatment | Journal of Cardiac Failure | 2010 | 218 |
6 | The renin-angiotensin system: going beyond the classical paradigms | American Journal of Physiology - Heart and Circulatory Physiology | 2019 | 218 |
7 | Short-term, long-term and paracrine effect of human umbilical cord-derived stem cells in lung injury prevention and repair in experimental bronchopulmonary dysplasia | Thorax | 2013 | 217 |
8 | Prevention of Angiotensin II–Mediated Renal Oxidative Stress, Inflammation, and Fibrosis by Angiotensin-Converting Enzyme 2 | Hypertension | 2011 | 200 |
9 | Left Ventricular Ejection Fraction and Volumes: It Depends on the Imaging Method | Echocardiography | 2014 | 189 |
10 | Mortality and Readmission of Patients With Heart Failure, Atrial Fibrillation, or Coronary Artery Disease Undergoing Noncardiac Surgery | Circulation | 2011 | 186 |
11 | Angiotensin 1–7 Ameliorates Diabetic Cardiomyopathy and Diastolic Dysfunction in db/db Mice by Reducing Lipotoxicity and Inflammation | Circulation: Heart Failure | 2014 | 158 |
12 | Characteristics and outcomes of patients with acute myocardial infarction and angiographically normal coronary arteries | American Journal of Cardiology | 2005 | 152 |
13 | Loss of Angiotensin-Converting Enzyme-2 Exacerbates Diabetic Cardiovascular Complications and Leads to Systolic and Vascular Dysfunction | Circulation Research | 2012 | 141 |
14 | Type 1 diabetic cardiomyopathy in the Akita (Ins2WT/C96Y) mouse model is characterized by lipotoxicity and diastolic dysfunction with preserved systolic function | American Journal of Physiology - Heart and Circulatory Physiology | 2009 | 139 |
15 | Prognostic Implications of Raphe in Bicuspid Aortic Valve Anatomy | JAMA Cardiology | 2017 | 101 |
16 | Tumor necrosis factor induces matrix metalloproteinases in cardiomyocytes and cardiofibroblasts differentially via superoxide production in a PI3Kγ-dependent manner | American Journal of Physiology - Cell Physiology | 2010 | 98 |
17 | Cardioprotective Effects Mediated by Angiotensin II Type 1 Receptor Blockade and Enhancing Angiotensin 1-7 in Experimental Heart Failure in Angiotensin-Converting Enzyme 2–Null Mice | Hypertension | 2012 | 97 |
18 | Myocardial ATGL Overexpression Decreases the Reliance on Fatty Acid Oxidation and Protects against Pressure Overload-Induced Cardiac Dysfunction | Molecular and Cellular Biology | 2012 | 95 |
19 | Quality of life after coronary revascularization in the elderly | European Heart Journal | 2006 | 93 |
20 | Disrupting the key circadian regulator CLOCK leads to age-dependent cardiovascular disease | Journal of Molecular and Cellular Cardiology | 2017 | 83 |
21 | Correlation of cardiovascular magnetic resonance imaging findings and endomyocardial biopsy results in patients undergoing screening for heart transplant rejection | Journal of Heart and Lung Transplantation | 2015 | 77 |
22 | Enhanced susceptibility to biomechanical stress in ACE2 null mice is prevented by loss of the p47phox NADPH oxidase subunit | Cardiovascular Research | 2011 | 76 |
23 | Trends in Readmissions and Length of Stay for Patients Hospitalized With Heart Failure in Canada and the United States | JAMA Cardiology | 2019 | 75 |
24 | Systolic and Diastolic Function Assessment in Fabry Disease Patients Using Speckle-Tracking Imaging and Comparison with Conventional Echocardiographic Measurements | Journal of the American Society of Echocardiography | 2013 | 72 |
25 | Angiotensin receptor blockers and risk of myocardial infarction: systematic review | BMJ: British Medical Journal | 2005 | 67 |
26 | Role of ACE2 in diastolic and systolic heart failure | Heart Failure Reviews | 2012 | 63 |
27 | Sex Differences in Phenotypes of Bicuspid Aortic Valve and Aortopathy | Circulation: Cardiovascular Imaging | 2017 | 63 |
28 | Recombinant Human Angiotensin-Converting Enzyme 2 as a New Renin-Angiotensin System Peptidase for Heart Failure Therapy | Current Heart Failure Reports | 2011 | 62 |
29 | Anderson-Fabry cardiomyopathy: prevalence, pathophysiology, diagnosis and treatment | Heart Failure Reviews | 2015 | 58 |
30 | The relationship between left ventricular ejection fraction and mortality in patients with acute heart failure: insights from the ASCEND‐HF Trial | European Journal of Heart Failure | 2014 | 56 |
31 | Beta blockers and improved progression-free survival in patients with advanced HER2 negative breast cancer: a retrospective analysis of the ROSE/TRIO-012 study | Annals of Oncology | 2017 | 52 |
32 | Loss of p47 phox Subunit Enhances Susceptibility to Biomechanical Stress and Heart Failure Because of Dysregulation of Cortactin and Actin Filaments | Circulation Research | 2013 | 51 |
33 | Prolonged strenuous exercise alters the cardiovascular response to dobutamine stimulation in male athletes | Journal of Physiology | 2005 | 50 |
34 | Loss of PI3Kγ Enhances cAMP-Dependent MMP Remodeling of the Myocardial N-Cadherin Adhesion Complexes and Extracellular Matrix in Response to Early Biomechanical Stress | Circulation Research | 2010 | 50 |
35 | MELAS syndrome and cardiomyopathy: linking mitochondrial function to heart failure pathogenesis | Heart Failure Reviews | 2016 | 50 |
36 | The Cardio-oncology Program: A Multidisciplinary Approach to the Care of Cancer Patients With Cardiovascular Disease | Canadian Journal of Cardiology | 2016 | 49 |
37 | Effect of low-carbohydrate diets on cardiometabolic risk, insulin resistance, and metabolic syndrome | Current Opinion in Endocrinology, Diabetes and Obesity | 2020 | 45 |
38 | Deletion of p47 phox attenuates the progression of diabetic nephropathy and reduces the severity of diabetes in the Akita mouse | Diabetologia | 2012 | 41 |
39 | Loss of Angiotensin-Converting Enzyme 2 Exacerbates Myocardial Injury via Activation of the CTGF-Fractalkine Signaling Pathway | Circulation Journal | 2013 | 40 |
40 | Determinants of Early Readmission After Hospitalization for Heart Failure | Canadian Journal of Cardiology | 2014 | 40 |
41 | S4153R Is a Gain-of-Function Mutation in the Cardiac Ca2+ Release Channel Ryanodine Receptor Associated With Catecholaminergic Polymorphic Ventricular Tachycardia and Paroxysmal Atrial Fibrillation | Canadian Journal of Cardiology | 2013 | 39 |
42 | Treating the right patient at the right time: Access to cardiac catheterization, percutaneous coronary intervention and cardiac surgery | Canadian Journal of Cardiology | 2006 | 38 |
43 | The Correlation of Standard Heart Failure Assessment and Palliative Care Questionnaires in a Multidisciplinary Heart Failure Clinic | Journal of Pain and Symptom Management | 2011 | 38 |
44 | Heart failure with preserved ejection fraction in the elderly: scope of the problem | Heart Failure Reviews | 2012 | 38 |
45 | Antagonism of angiotensin 1–7 prevents the therapeutic effects of recombinant human ACE2 | Journal of Molecular Medicine | 2015 | 38 |
46 | Angiotensin-converting enzyme 2 ameliorates renal fibrosis by blocking the activation of mTOR/ERK signaling in apolipoprotein E-deficient mice | Peptides | 2016 | 36 |
47 | A Review on Diffusion of Personal Digital Assistants in Healthcare | Journal of Medical Systems | 2005 | 35 |
48 | Heterozygote loss of ACE2 is sufficient to increase the susceptibility to heart disease | Journal of Molecular Medicine | 2014 | 34 |
49 | Strategy of continued vs interrupted novel oral anticoagulant at time of device surgery in patients with moderate to high risk of arterial thromboembolic events: The BRUISE CONTROL-2 trial | American Heart Journal | 2016 | 34 |
50 | Direct and indirect costs of management of long-term warfarin therapy in Canada | Journal of Thrombosis and Haemostasis | 2010 | 33 |