# | Title | Journal | Year | Citations |
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1 | Revisions to the Classification, Nomenclature, and Diversity of Eukaryotes | Journal of Eukaryotic Microbiology | 2019 | 904 |
2 | The global preclinical antibacterial pipeline | Nature Reviews Microbiology | 2020 | 442 |
3 | Towards the sustainable discovery and development of new antibiotics | Nature Reviews Chemistry | 2021 | 439 |
4 | Biosynthesis, Natural Sources, Dietary Intake, Pharmacokinetic Properties, and Biological Activities of Hydroxycinnamic Acids | Journal of Agricultural and Food Chemistry | 2012 | 334 |
5 | Marine Natural Products: A Source of Novel Anticancer Drugs | Marine Drugs | 2019 | 324 |
6 | Design, Synthesis, and Biological Evaluation of the First Selective Nonpeptide AT2Receptor Agonist | Journal of Medicinal Chemistry | 2004 | 317 |
7 | Ru(arene)(amino alcohol)-Catalyzed Transfer Hydrogenation of Ketones: Mechanism and Origin of Enantioselectivity | Journal of the American Chemical Society | 1999 | 299 |
8 | Prospective of 68Ga-Radiopharmaceutical Development | Theranostics | 2014 | 265 |
9 | Novel Chemical Space Exploration via Natural Products | Journal of Medicinal Chemistry | 2009 | 248 |
10 | Metal nanoparticles fabricated by green chemistry using natural extracts: biosynthesis, mechanisms, and applications | RSC Advances | 2019 | 247 |
11 | Crystal structure of the heterodimeric complex of LXR and RXR ligand-binding domains in a fully agonistic conformation | EMBO Journal | 2003 | 246 |
12 | Distribution and Evolution of Circular Miniproteins in Flowering Plants | Plant Cell | 2008 | 234 |
13 | In Vivo Visualization of Amyloid Deposits in the Heart with 11C-PIB and PET | Journal of Nuclear Medicine | 2013 | 219 |
14 | Mechanistic Studies of Copper-Catalyzed Alkene Aziridination | Journal of the American Chemical Society | 2000 | 212 |
15 | ChemGPS-NP: Tuned for Navigation in Biologically Relevant Chemical Space | Journal of Natural Products | 2007 | 199 |
16 | COX-2 Inhibitory Effects of Naturally Occurring and Modified Fatty Acids | Journal of Natural Products | 2001 | 190 |
17 | Cyclotides: a novel type of cytotoxic agents | Molecular Cancer Therapeutics | 2002 | 181 |
18 | The cyclotide cycloviolacin O2 from Viola odorata has potent bactericidal activity against Gram-negative bacteria | Journal of Antimicrobial Chemotherapy | 2010 | 179 |
19 | Cytotoxic Cyclotides fromViolatricolor⊥ | Journal of Natural Products | 2004 | 176 |
20 | Microglia: Agents of the CNS Pro-Inflammatory Response | Cells | 2020 | 174 |
21 | Survey and qualification of internal standards for quantification by 1H NMR spectroscopy | Journal of Pharmaceutical and Biomedical Analysis | 2010 | 171 |
22 | Dioxygen-Promoted Regioselective Oxidative Heck Arylations of Electron-Rich Olefins with Arylboronic Acids | Journal of Organic Chemistry | 2004 | 167 |
23 | Biogenesis of ZnO nanoparticles using Pandanus odorifer leaf extract: anticancer and antimicrobial activities | RSC Advances | 2019 | 166 |
24 | Lignin depolymerization to monophenolic compounds in a flow-through system | Green Chemistry | 2017 | 164 |
25 | Antibody-based PET imaging of amyloid beta in mouse models of Alzheimer’s disease | Nature Communications | 2016 | 155 |
26 | APR-246 overcomes resistance to cisplatin and doxorubicin in ovarian cancer cells | Cell Death and Disease | 2015 | 151 |
27 | Plasmepsins as potential targets for new antimalarial therapy | Medicinal Research Reviews | 2006 | 149 |
28 | Comprehensive mapping of neurotransmitter networks by MALDI–MS imaging | Nature Methods | 2019 | 148 |
29 | Reversible Antifouling Effect of the Cyclotide Cycloviolacin O2 against Barnacles | Journal of Natural Products | 2004 | 144 |
30 | Recent Insights into the Biosynthesis and Biological Activities of Natural Xanthones | Current Medicinal Chemistry | 2010 | 142 |
31 | Recent Developments in Microwave‐Assisted, Transition‐Metal‐Catalysed C–C and C–N Bond‐Forming Reactions | European Journal of Organic Chemistry | 2008 | 141 |
32 | Transplantation of macroencapsulated human islets within the bioartificial pancreas βAir to patients with type 1 diabetes mellitus | American Journal of Transplantation | 2018 | 140 |
33 | Microwave‐Promoted Palladium(II)‐Catalyzed CP Bond Formation by Using Arylboronic Acids or Aryltrifluoroborates | Chemistry - A European Journal | 2009 | 132 |
34 | Mechanism of Action of Cytotoxic Cyclotides: Cycloviolacin O2 Disrupts Lipid Membranes | Journal of Natural Products | 2007 | 131 |
35 | The alpine violet, Viola biflora, is a rich source of cyclotides with potent cytotoxicity | Phytochemistry | 2008 | 131 |
36 | Stimulation of angiotensin AT2 receptors by the non‐peptide agonist, Compound 21, evokes vasodepressor effects in conscious spontaneously hypertensive rats | British Journal of Pharmacology | 2010 | 131 |
37 | Oxytocic plant cyclotides as templates for peptide G protein-coupled receptor ligand design | Proceedings of the National Academy of Sciences of the United States of America | 2013 | 129 |
38 | Overeating Saturated Fat Promotes Fatty Liver and Ceramides Compared With Polyunsaturated Fat: A Randomized Trial | Journal of Clinical Endocrinology and Metabolism | 2019 | 124 |
39 | Efficient Palladium(II) Catalysis under Air. Base-Free Oxidative Heck Reactions at Room Temperature or with Microwave Heating | Journal of Organic Chemistry | 2007 | 120 |
40 | Prediction and Identification of Drug Interactions with the Human ATP-Binding Cassette Transporter Multidrug-Resistance Associated Protein 2 (MRP2; ABCC2) | Journal of Medicinal Chemistry | 2008 | 119 |
41 | Oral activity of a nature-derived cyclic peptide for the treatment of multiple sclerosis | Proceedings of the National Academy of Sciences of the United States of America | 2016 | 119 |
42 | St John's wort decreases the bioavailability of R- and S-verapamil through induction of the first-pass metabolism*1 | Clinical Pharmacology and Therapeutics | 2004 | 118 |
43 | Ultralarge Virtual Screening Identifies SARS-CoV-2 Main Protease Inhibitors with Broad-Spectrum Activity against Coronaviruses | Journal of the American Chemical Society | 2022 | 118 |
44 | Synthesis of Aryl Ketones by Palladium(II)‐Catalyzed Decarboxylative Addition of Benzoic Acids to Nitriles | Angewandte Chemie - International Edition | 2010 | 116 |
45 | Quantitative detection of apple watercore and soluble solids content by near infrared transmittance spectroscopy | Journal of Food Engineering | 2020 | 116 |
46 | Sulfonyl Fluorides (SFs): More Than Click Reagents? | European Journal of Organic Chemistry | 2018 | 115 |
47 | Prehistoric peyote use: Alkaloid analysis and radiocarbon dating of archaeological specimens of Lophophora from Texas | Journal of Ethnopharmacology | 2005 | 114 |
48 | Microwave-Enhanced Aminocarbonylations in Water | Organic Letters | 2005 | 112 |
49 | The Many Faces of Kefir Fermented Dairy Products: Quality Characteristics, Flavour Chemistry, Nutritional Value, Health Benefits, and Safety | Nutrients | 2020 | 112 |
50 | Vinyl Sulfide Cyclized Analogues of Angiotensin II with High Affinity and Full Agonist Activity at the AT1Receptor | Journal of Medicinal Chemistry | 2002 | 111 |