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Top Articles

#TitleJournalYearCitations
1The inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteriaProceedings of the National Academy of Sciences of the United States of America20081,657
2Mechanisms of Pancreatic  -Cell Death in Type 1 and Type 2 Diabetes: Many Differences, Few SimilaritiesDiabetes20051,296
3A spectrophotometric method for determination of catalase activity in small tissue samplesAnalytical Biochemistry1988821
4VEGFA and tumour angiogenesisJournal of Internal Medicine2013635
5The neutrophil in vascular inflammationNature Medicine2011607
6Opposite effects of tolbutamide and diazoxide on the ATP-dependent K+ channel in mouse pancreatic ?-cellsPflugers Archiv European Journal of Physiology1986545
7Female Mice are Protected against High-Fat Diet Induced Metabolic Syndrome and Increase the Regulatory T Cell Population in Adipose TissuePLoS ONE2012395
8Markedly Decreased Oxygen Tension in Transplanted Rat Pancreatic Islets Irrespective of the Implantation SiteDiabetes2001365
9Interleukin-lβ-Induced Nitric Oxide Production in Isolated Rat Pancreatic Islets Requires Gene Transcription and May Lead to Inhibition of the Krebs Cycle Enzyme Aconitase*Endocrinology1991333
10Dietary inorganic nitrate reverses features of metabolic syndrome in endothelial nitric oxide synthase-deficient miceProceedings of the National Academy of Sciences of the United States of America2010316
11A mammalian functional nitrate reductase that regulates nitrite and nitric oxide homeostasisNature Chemical Biology2008302
12Importance and regulation of the colonic mucus barrier in a mouse model of colitisAmerican Journal of Physiology - Renal Physiology2011302
13The harmony of the spheres: inducible nitric oxide synthase and related genes in pancreatic beta cellsDiabetologia1996298
14Inhibitory Effects of Interleukin 1 on Insulin Secretion, Insulin Biosynthesis, and Oxidative Metabolism of Isolated Rat Pancreatic Islets*Endocrinology1987296
15Bacteria Penetrate the Inner Mucus Layer before Inflammation in the Dextran Sulfate Colitis ModelPLoS ONE2010288
16Prolonged exposure of human pancreatic islets to high glucose concentrations in vitro impairs the beta-cell function.Journal of Clinical Investigation1992286
17Modulation of Shigella virulence in response to available oxygen in vivoNature2010286
18Reactive oxygen species cause diabetes-induced decrease in renal oxygen tensionDiabetologia2003284
19Cytokines Induce Deoxyribonucleic Acid Strand Breaks and Apoptosis in Human Pancreatic Islet Cells*Endocrinology1997282
20Cytokines suppress human islet function irrespective of their effects on nitric oxide generation.Journal of Clinical Investigation1994278
21Inflammation and Structural Changes in the Airways of Patients with Atopic and Nonatopic AsthmaAmerican Journal of Respiratory and Critical Care Medicine2000275
22VEGF-A recruits a proangiogenic MMP-9–delivering neutrophil subset that induces angiogenesis in transplanted hypoxic tissueBlood2012275
23β-Cell Loss and β-Cell Apoptosis in Human Type 2 Diabetes Are Related to Islet Amyloid DepositionAmerican Journal of Pathology2011271
24Roles of dietary inorganic nitrate in cardiovascular health and diseaseCardiovascular Research2011268
25Angiotensin II and the endocrine pancreas: effects on islet blood flow and insulin secretion in ratsDiabetologia1998266
26Major species differences between humans and rodents in the susceptibility to pancreatic beta-cell injury.Proceedings of the National Academy of Sciences of the United States of America1994249
27Protection by free oxygen radical scavenging enzymes against glucose-induced embryonic malformations in vitroDiabetologia1991248
28SARS-CoV-2 exposure, symptoms and seroprevalence in healthcare workers in SwedenNature Communications2020243
29Graft vascular function after transplantation of pancreatic isletsDiabetologia2002239
30Oscillations of cyclic AMP in hormone-stimulated insulin-secreting β-cellsNature2006236
31In Vivo Seeding and Cross-Seeding of Localized AmyloidosisAmerican Journal of Pathology2015235
32Preserved β-Cell Function in Type 1 Diabetes by Mesenchymal Stromal CellsDiabetes2015235
33Synchronous oscillations of cytoplasmic Ca2+ and insulin release in glucose-stimulated pancreatic islets.Journal of Biological Chemistry1994232
34The Physiology of Leukocyte Recruitment: An In Vivo PerspectiveJournal of Immunology2008230
35The Adaptor Protein Shb Binds to Tyrosine 1175 in Vascular Endothelial Growth Factor (VEGF) Receptor-2 and Regulates VEGF-dependent Cellular MigrationJournal of Biological Chemistry2004225
36Dietary nitrate attenuates oxidative stress, prevents cardiac and renal injuries, and reduces blood pressure in salt-induced hypertensionCardiovascular Research2011216
37Determinants of kidney oxygen consumption and their relationship to tissue oxygen tension in diabetes and hypertensionClinical and Experimental Pharmacology and Physiology2013216
38Sodium Palmitate Induces Partial Mitochondrial Uncoupling and Reactive Oxygen Species in Rat Pancreatic Isletsin Vitro1Endocrinology1999214
39Stimulation by glucose of the blood flow to the pancreatic islets of the ratDiabetologia1983211
40Diabetes and Embryonic Malformations: Role of Substrate-Induced Free-Oxygen Radical Production for Dysmorphogenesis in Cultured Rat EmbryosDiabetes1993210
41AA Amyloidosis: Pathogenesis and Targeted TherapyAnnual Review of Pathology: Mechanisms of Disease2015201
42Gastroprotective and blood pressure lowering effects of dietary nitrate are abolished by an antiseptic mouthwashFree Radical Biology and Medicine2009200
43Decreased Vascular Density in Mouse Pancreatic Islets After TransplantationDiabetes2002196
44Human Astrocytes Transfer Aggregated Alpha-Synuclein via Tunneling NanotubesJournal of Neuroscience2017196
45Hyperthermia induced pathophysiology of the central nervous systemInternational Journal of Hyperthermia2003194
46VEGFR2 induces c-Src signaling and vascular permeability in vivo via the adaptor protein TSAdJournal of Experimental Medicine2012194
47Increased Melatonin Signaling Is a Risk Factor for Type 2 DiabetesCell Metabolism2016194
48The Healing Power of NeutrophilsTrends in Immunology2019193
49Glucose inhibits glucagon secretion by a direct effect on mouse pancreatic alpha cellsDiabetologia2007182
50A chemotactic gradient sequestered on endothelial heparan sulfate induces directional intraluminal crawling of neutrophilsBlood2010180