| # | Title | Journal | Year | Citations |
|---|
| 1 | Modeling the epidemic of nonalcoholic fatty liver disease demonstrates an exponential increase in burden of disease | Hepatology | 2018 | 1,474 |
| 2 | Formation of nitric oxide-derived inflammatory oxidants by myeloperoxidase in neutrophils | Nature | 1998 | 1,452 |
| 3 | Fibrosis Progression in Nonalcoholic Fatty Liver vs Nonalcoholic Steatohepatitis: A Systematic Review and Meta-analysis of Paired-Biopsy Studies | Clinical Gastroenterology and Hepatology | 2015 | 1,199 |
| 4 | Incidence of Venous Thromboembolism and Its Effect on Survival Among Patients With Common Cancers | Archives of Internal Medicine | 2006 | 1,012 |
| 5 | Idiopathic pulmonary fibrosis | Nature Reviews Disease Primers | 2017 | 786 |
| 6 | Formation of Reactive Nitrogen Species during Peroxidase-catalyzed Oxidation of Nitrite | Journal of Biological Chemistry | 1997 | 735 |
| 7 | Evaluation, Diagnosis, and Treatment of Gastrointestinal Disorders in Individuals With ASDs: A Consensus Report | Pediatrics | 2010 | 690 |
| 8 | Myeloperoxidase, a Leukocyte-Derived Vascular NO Oxidase | Science | 2002 | 631 |
| 9 | Hypoxic Preconditioning Results in Increased Motility and Improved Therapeutic Potential of Human Mesenchymal Stem Cells | Stem Cells | 2008 | 609 |
| 10 | Intravenous N-Acetylcysteine Improves Transplant-Free Survival in Early Stage Non-Acetaminophen Acute Liver Failure | Gastroenterology | 2009 | 573 |
| 11 | Effectiveness of Remote Patient Monitoring After Discharge of Hospitalized Patients With Heart Failure | JAMA Internal Medicine | 2016 | 528 |
| 12 | Lipopolysaccharide Causes an Increase in Intestinal Tight Junction Permeability in Vitro and in Vivo by Inducing Enterocyte Membrane Expression and Localization of TLR-4 and CD14 | American Journal of Pathology | 2013 | 498 |
| 13 | Wilson disease | Nature Reviews Disease Primers | 2018 | 466 |
| 14 | Mesenchymal stem cells for the treatment of neurodegenerative disease | Regenerative Medicine | 2010 | 452 |
| 15 | Induction of Inflammation in Vascular Endothelial Cells by Metal Oxide Nanoparticles: Effect of Particle Composition | Environmental Health Perspectives | 2007 | 435 |
| 16 | Control of cortical GABA circuitry development by Nrg1 and ErbB4 signalling | Nature | 2010 | 423 |
| 17 | Drug-Induced Liver Injury Network (DILIN) Prospective Study | Drug Safety | 2009 | 416 |
| 18 | Enzymatic and nonenzymatic cross‐linking of collagen and elastin | FASEB Journal | 1992 | 408 |
| 19 | Formation of Nitrating and Chlorinating Species by Reaction of Nitrite with Hypochlorous Acid | Journal of Biological Chemistry | 1996 | 408 |
| 20 | Amyloid-related imaging abnormalities in patients with Alzheimer's disease treated with bapineuzumab: a retrospective analysis | Lancet Neurology, The | 2012 | 390 |
| 21 | Protocol Weaning of Mechanical Ventilation in Medical and Surgical Patients by RespiratoryCare Practitioners and Nurses | Chest | 2000 | 383 |
| 22 | Tyrosine Modification by Reactive Nitrogen Species: A Closer Look | Archives of Biochemistry and Biophysics | 1995 | 380 |
| 23 | Mental disorders and subsequent educational attainment in a US national sample | Journal of Psychiatric Research | 2008 | 376 |
| 24 | Glycans in the immune system and The Altered Glycan Theory of Autoimmunity: A critical review | Journal of Autoimmunity | 2015 | 370 |
| 25 | The Role of the Immune System in Autism Spectrum Disorder | Neuropsychopharmacology | 2017 | 346 |
| 26 | Walnut Polyphenolics Inhibit In Vitro Human Plasma and LDL Oxidation | Journal of Nutrition | 2001 | 344 |
| 27 | Emergence of Diverse Helicobacter Species in the Pathogenesis of Gastric and Enterohepatic Diseases | Clinical Microbiology Reviews | 2001 | 325 |
| 28 | Venous Thromboembolism in Patients With Colorectal Cancer: Incidence and Effect on Survival | Journal of Clinical Oncology | 2006 | 325 |
| 29 | Twenty years post‐NIH Revitalization Act: Enhancing minority participation in clinical trials (EMPaCT): Laying the groundwork for improving minority clinical trial accrual | Cancer | 2014 | 323 |
| 30 | Endoscopic injection sclerosis in bleeding gastric varices | Gastrointestinal Endoscopy | 1986 | 322 |
| 31 | Risk of Serious Bacterial Infection in Young Febrile Infants With Respiratory Syncytial Virus Infections | Pediatrics | 2004 | 301 |
| 32 | Reactive Nitrogen Species and Tyrosine Nitration in the Respiratory Tract | American Journal of Respiratory and Critical Care Medicine | 1999 | 292 |
| 33 | The autoepitope of the 74-kD mitochondrial autoantigen of primary biliary cirrhosis corresponds to the functional site of dihydrolipoamide acetyltransferase. | Journal of Experimental Medicine | 1988 | 284 |
| 34 | Heart disease risk factors predict erectile dysfunction 25 years later | Journal of the American College of Cardiology | 2004 | 275 |
| 35 | Corticosteroids and wound healing: clinical considerations in the perioperative period | American Journal of Surgery | 2013 | 274 |
| 36 | Endothelial progenitor cell transplantation improves long‐term stroke outcome in mice | Annals of Neurology | 2010 | 271 |
| 37 | Copper, Zinc, Manganese, and Magnesium Status and Complications of Diabetes Mellitus | Diabetes Care | 1991 | 269 |
| 38 | Left Ventricular Unloading Is Associated With Lower Mortality in Patients With Cardiogenic Shock Treated With Venoarterial Extracorporeal Membrane Oxygenation | Circulation | 2020 | 269 |
| 39 | Effectiveness of syringe exchange programs in reducing HIV risk behavior and HIV seroconversion among injecting drug users | Aids | 2001 | 268 |
| 40 | In Vivo High Resolution MRI of the Calcaneus: Differences in Trabecular Structure in Osteoporosis Patients | Journal of Bone and Mineral Research | 1998 | 261 |
| 41 | Reduced-dose radiotherapy for human papillomavirus-associated squamous-cell carcinoma of the oropharynx: a single-arm, phase 2 study | Lancet Oncology, The | 2017 | 261 |
| 42 | No Significant Effects of Ethyl-Eicosapentanoic Acid on Histologic Features of Nonalcoholic Steatohepatitis in a Phase 2 Trial | Gastroenterology | 2014 | 260 |
| 43 | Metabolic Interactions of Alcohol and Folate | Journal of Nutrition | 2002 | 258 |
| 44 | Epoxy metabolites of docosahexaenoic acid (DHA) inhibit angiogenesis, tumor growth, and metastasis | Proceedings of the National Academy of Sciences of the United States of America | 2013 | 251 |
| 45 | The incidence of venous thromboembolism among patients with primary lung cancer | Journal of Thrombosis and Haemostasis | 2008 | 247 |
| 46 | Prolonged lymphocytosis during ibrutinib therapy is associated with distinct molecular characteristics and does not indicate a suboptimal response to therapy | Blood | 2014 | 246 |
| 47 | Hepatic stellate cells: a target for the treatment of liver fibrosis | Journal of Gastroenterology | 2000 | 244 |
| 48 | Molecular Identification and Functional Roles of a Ca2+-activated K+ Channel in Human and Mouse Hearts | Journal of Biological Chemistry | 2003 | 242 |
| 49 | Grade-Dependent Metabolic Reprogramming in Kidney Cancer Revealed by Combined Proteomics and Metabolomics Analysis | Cancer Research | 2015 | 236 |
| 50 | The Impact of Early Behavior Disturbances on Academic Achievement in High School | Pediatrics | 2009 | 230 |
