| Staphylococcus aureus sortase, an enzyme that anchors surface proteins to the cell wall | Science | 1999 | 795 |
| PTEN modulates cell cycle progression and cell survival by regulating phosphatidylinositol 3,4,5,-trisphosphate and Akt/protein kinase B signaling pathway | Proceedings of the National Academy of Sciences of the United States of America | 1999 | 662 |
| The CD1 system: antigen-presenting molecules for T cell recognition of lipids and glycolipids | Annual Review of Immunology | 1999 | 592 |
| Cytotoxic T-cell immunity to virus-infected non-haematopoietic cells requires presentation of exogenous antigen | Nature | 1999 | 488 |
| Chronic Lymphocytic Leukemia B Cells Express Functional CXCR4 Chemokine Receptors That Mediate Spontaneous Migration Beneath Bone Marrow Stromal Cells | Blood | 1999 | 391 |
| Identification of an MHC class I-restricted autoantigen in type 1 diabetes by screening an organ-specific cDNA library | Nature Medicine | 1999 | 375 |
| Telomerase extends the lifespan of virus-transformed human cells without net telomere lengthening | Proceedings of the National Academy of Sciences of the United States of America | 1999 | 328 |
| The 193-kD vault protein, VPARP, is a novel poly(ADP-ribose) polymerase | Journal of Cell Biology | 1999 | 327 |
| Identification of a mating type-like locus in the asexual pathogenic yeast Candida albicans | Science | 1999 | 322 |
| EGF receptor signaling stimulates SRC kinase phosphorylation of clathrin, influencing clathrin redistribution and EGF uptake | Cell | 1999 | 299 |
| Integrin cytoplasmic tyrosine motif is required for outside-in alphaIIbbeta3 signalling and platelet function | Nature | 1999 | 289 |
| Coordinate regulation of B cell differentiation by the transcription factors EBF and E2A | Immunity | 1999 | 275 |
| Nasal challenge with diesel exhaust particles can induce sensitization to a neoallergen in the human mucosa | Journal of Allergy and Clinical Immunology | 1999 | 267 |
| Sulfotransferases of two specificities function in the reconstitution of high endothelial cell ligands for L-selectin | Journal of Cell Biology | 1999 | 248 |
| Chemokine receptor expression by human intestinal epithelial cells | Gastroenterology | 1999 | 212 |
| Structurally similar oxidized phospholipids differentially regulate endothelial binding of monocytes and neutrophils | Proceedings of the National Academy of Sciences of the United States of America | 1999 | 207 |
| An immunophenotypic study of canine leukemias and preliminary assessment of clonality by polymerase chain reaction | Veterinary Immunology and Immunopathology | 1999 | 191 |
| A role for perforin in downregulating T-cell responses during chronic viral infection | Journal of Virology | 1999 | 183 |
| Increased anxiety and altered responses to anxiolytics in mice deficient in the 65-kDa isoform of glutamic acid decarboxylase | Proceedings of the National Academy of Sciences of the United States of America | 1999 | 180 |
| Signal transduction and transcription factors in rheumatic disease | Arthritis and Rheumatism | 1999 | 173 |
| The role of the synthetic enzyme GAD65 in the control of neuronal gamma-aminobutyric acid release | Proceedings of the National Academy of Sciences of the United States of America | 1999 | 156 |
| Endothelial ligands for L-selectin: from lymphocyte recirculation to allograft rejection | American Journal of Pathology | 1999 | 151 |
| Deregulated signal transduction by the K1 gene product of Kaposi's sarcoma-associated herpesvirus | Proceedings of the National Academy of Sciences of the United States of America | 1999 | 141 |
| Cutting edge: adenovirus E19 has two mechanisms for affecting class I MHC expression | Journal of Immunology | 1999 | 139 |
| Yersinia enterocolitica type III secretion: an mRNA signal that couples translation and secretion of YopQ | Molecular Microbiology | 1999 | 133 |
