| # | Title | Journal | Year | Citations |
|---|
| 1 | Inflammation and cancer | Nature | 2002 | 12,666 |
| 2 | Neurotrophins: Roles in Neuronal Development and Function | Annual Review of Neuroscience | 2001 | 3,712 |
| 3 | Understanding the tumor immune microenvironment (TIME) for effective therapy | Nature Medicine | 2018 | 3,421 |
| 4 | Guidelines for the use and interpretation of assays for monitoring autophagy | Autophagy | 2012 | 3,122 |
| 5 | Chronic inflammation in the etiology of disease across the life span | Nature Medicine | 2019 | 2,195 |
| 6 | Paradoxical roles of the immune system during cancer development | Nature Reviews Cancer | 2006 | 1,979 |
| 7 | National Institute on Aging–Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease | Alzheimer's and Dementia | 2012 | 1,968 |
| 8 | Comprehensive Molecular Characterization of Muscle-Invasive Bladder Cancer | Cell | 2017 | 1,742 |
| 9 | Tumor Angiogenesis: A New Significant and Independent Prognostic Indicator in Early-Stage Breast Carcinoma | Journal of the National Cancer Institute | 1992 | 1,688 |
| 10 | Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase | Nature Genetics | 1995 | 1,609 |
| 11 | Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein | Nature | 1992 | 1,582 |
| 12 | The Aryl Hydrocarbon Receptor Complex | Annual Review of Pharmacology and Toxicology | 1995 | 1,506 |
| 13 | Leukocyte Complexity Predicts Breast Cancer Survival and Functionally Regulates Response to Chemotherapy | Cancer Discovery | 2011 | 1,486 |
| 14 | VEGF in Signaling and Disease: Beyond Discovery and Development | Cell | 2019 | 1,468 |
| 15 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
| 16 | Aquaporin-4 deletion in mice reduces brain edema after acute water intoxication and ischemic stroke | Nature Medicine | 2000 | 1,415 |
| 17 | Dendritic cells in cancer immunology and immunotherapy | Nature Reviews Immunology | 2020 | 1,401 |
| 18 | Prevalence of Fatty Liver in Children and Adolescents | Pediatrics | 2006 | 1,264 |
| 19 | Natural versus adaptive regulatory T cells | Nature Reviews Immunology | 2003 | 1,218 |
| 20 | Tumor angiogenesis correlates with metastasis in invasive prostate carcinoma | American Journal of Pathology | 1993 | 1,162 |
| 21 | Datamonkey 2010: a suite of phylogenetic analysis tools for evolutionary biology | Bioinformatics | 2010 | 1,158 |
| 22 | Mutational Analysis Reveals the Origin and Therapy-Driven Evolution of Recurrent Glioma | Science | 2014 | 1,147 |
| 23 | CD4+ T Cells Regulate Pulmonary Metastasis of Mammary Carcinomas by Enhancing Protumor Properties of Macrophages | Cancer Cell | 2009 | 1,135 |
| 24 | The translational landscape of mTOR signalling steers cancer initiation and metastasis | Nature | 2012 | 1,114 |
| 25 | Regulation of Intestinal -Defensin Activation by the Metalloproteinase Matrilysin in Innate Host Defense | Science | 1999 | 1,041 |
| 26 | Lytic growth of Kaposi's sarcoma–associated herpesvirus (human herpesvirus 8) in culture | Nature Medicine | 1996 | 1,024 |
| 27 | Protective effect of high density lipoprotein associated paraoxonase. Inhibition of the biological activity of minimally oxidized low density lipoprotein. | Journal of Clinical Investigation | 1995 | 1,012 |
| 28 | Family income, parental education and brain structure in children and adolescents | Nature Neuroscience | 2015 | 979 |
| 29 | The perivascular niche regulates breast tumour dormancy | Nature Cell Biology | 2013 | 945 |
| 30 | Secretion of microbicidal α-defensins by intestinal Paneth cells in response to bacteria | Nature Immunology | 2000 | 939 |
| 31 | Neoadjuvant anti-PD-1 immunotherapy promotes a survival benefit with intratumoral and systemic immune responses in recurrent glioblastoma | Nature Medicine | 2019 | 932 |
| 32 | High-throughput oncogene mutation profiling in human cancer | Nature Genetics | 2007 | 927 |
| 33 | Cloning of a factor required for activity of the Ah (dioxin) receptor | Science | 1991 | 910 |
| 34 | Nitric oxide synthase complexed with dystrophin and absent from skeletal muscle sarcolemma in Duchenne muscular dystrophy | Cell | 1995 | 907 |
| 35 | Suppression of the neoplastic phenotype by replacement of the RB gene in human cancer cells | Science | 1988 | 884 |
| 36 | Primary brain tumours in adults | Lancet, The | 2018 | 882 |
| 37 | Transgenetic studies implicate interactions between homologous PrP isoforms in scrapie prion replication | Cell | 1990 | 877 |
| 38 | Minimally modified low density lipoprotein stimulates monocyte endothelial interactions. | Journal of Clinical Investigation | 1990 | 862 |
| 39 | Prion Protein Biology | Cell | 1998 | 856 |
| 40 | The Retardation of Aging in Mice by Dietary Restriction: Longevity, Cancer, Immunity and Lifetime Energy Intake | Journal of Nutrition | 1986 | 855 |
| 41 | Phenotype and kinetics of SARS-CoV-2–specific T cells in COVID-19 patients with acute respiratory distress syndrome | Science Immunology | 2020 | 851 |
| 42 | Specificity in Toll-like receptor signalling through distinct effector functions of TRAF3 and TRAF6 | Nature | 2006 | 836 |
| 43 | The lung is a site of platelet biogenesis and a reservoir for haematopoietic progenitors | Nature | 2017 | 805 |
| 44 | Prion propagation in mice expressing human and chimeric PrP transgenes implicates the interaction of cellular PrP with another protein | Cell | 1995 | 800 |
| 45 | Hyaluronic acid: a natural biopolymer with a broad range of biomedical and industrial applications | Biotechnology Letters | 2006 | 795 |
| 46 | Development and Use of Personalized Bacteriophage-Based Therapeutic Cocktails To Treat a Patient with a Disseminated Resistant Acinetobacter baumannii Infection | Antimicrobial Agents and Chemotherapy | 2017 | 795 |
| 47 | Differential effects of apolipoproteins E3 and E4 on neuronal growth in vitro | Science | 1994 | 793 |
| 48 | Acetylation of Tau Inhibits Its Degradation and Contributes to Tauopathy | Neuron | 2010 | 772 |
| 49 | GARD: a genetic algorithm for recombination detection | Bioinformatics | 2006 | 750 |
| 50 | Identification of the Ah Receptor Nuclear Translocator Protein (Arnt) as a Component of the DNA Binding Form of the Ah Receptor | Science | 1992 | 743 |
