Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion | Nature | 2012 | 1.3K |
Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma | Nature Genetics | 2012 | 887 |
Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity | Nature Genetics | 2012 | 681 |
Melanoma whole-exome sequencing identifies (V600E)B-RAF amplification-mediated acquired B-RAF inhibitor resistance | Nature Communications | 2012 | 500 |
The helicase DDX41 recognizes the bacterial secondary messengers cyclic di-GMP and cyclic di-AMP to activate a type I interferon immune response | Nature Immunology | 2012 | 286 |
Ultraviolet radiation damages self noncoding RNA and is detected by TLR3 | Nature Medicine | 2012 | 286 |
Antimicrobial peptides: old molecules with new ideas | Journal of Investigative Dermatology | 2012 | 244 |
Etiology and management of pyoderma gangrenosum: a comprehensive review | American Journal of Clinical Dermatology | 2012 | 239 |
Rare and common variants in CARD14, encoding an epidermal regulator of NF-kappaB, in psoriasis | American Journal of Human Genetics | 2012 | 239 |
Donor B-cell alloantibody deposition and germinal center formation are required for the development of murine chronic GVHD and bronchiolitis obliterans | Blood | 2012 | 178 |
The antimicrobial protein REG3A regulates keratinocyte proliferation and differentiation after skin injury | Immunity | 2012 | 162 |
Hypersensitivity reactions to metallic implants - diagnostic algorithm and suggested patch test series for clinical use | Contact Dermatitis | 2012 | 143 |
Antimicrobial peptides in the pathogenesis of psoriasis | Journal of Dermatology | 2012 | 136 |
Cathelicidin antimicrobial peptide LL-37 in psoriasis enables keratinocyte reactivity against TLR9 ligands | Journal of Investigative Dermatology | 2012 | 134 |
Glucose deprivation activates a metabolic and signaling amplification loop leading to cell death | Molecular Systems Biology | 2012 | 132 |
Patient attitudes toward the use of fecal microbiota transplantation in the treatment of recurrent Clostridium difficile infection | Clinical Infectious Diseases | 2012 | 127 |
Pemphigus autoimmunity: hypotheses and realities | Autoimmunity | 2012 | 124 |
The double-edged sword of Notch signaling in cancer | Seminars in Cell and Developmental Biology | 2012 | 120 |
Early growth of infantile hemangiomas: what parents' photographs tell us | Pediatrics | 2012 | 120 |
Treating human autoimmunity: current practice and future prospects | Science Translational Medicine | 2012 | 119 |
A pilot study of an oral phosphodiesterase inhibitor (apremilast) for atopic dermatitis in adults | Archives of Dermatology | 2012 | 110 |
The antimicrobial and osteoinductive properties of silver nanoparticle/poly (DL-lactic-co-glycolic acid)-coated stainless steel | Biomaterials | 2012 | 104 |
A subset of methylated CpG sites differentiate psoriatic from normal skin | Journal of Investigative Dermatology | 2012 | 104 |
Mutated regions of nucleophosmin 1 elicit both CD4(+) and CD8(+) T-cell responses in patients with acute myeloid leukemia | Blood | 2012 | 100 |
Host immune defense peptide LL-37 activates caspase-independent apoptosis and suppresses colon cancer | Cancer Research | 2012 | 88 |