| # | Title | Journal | Year | Citations |
|---|
| 1 | Mutations in NOTCH1 cause aortic valve disease | Nature | 2005 | 1,274 |
| 2 | Polycystic ovary syndrome | Nature Reviews Disease Primers | 2016 | 1,004 |
| 3 | Non-lethal Inhibition of Gut Microbial Trimethylamine Production for the Treatment of Atherosclerosis | Cell | 2015 | 974 |
| 4 | Multislice Computed Tomographic Characteristics of Coronary Lesions in Acute Coronary Syndromes | Journal of the American College of Cardiology | 2007 | 936 |
| 5 | Bone morphogenetic protein expression in human atherosclerotic lesions. | Journal of Clinical Investigation | 1993 | 918 |
| 6 | Cardiovascular Effects of Secondhand Smoke | Circulation | 2005 | 815 |
| 7 | IRF3 Mediates a TLR3/TLR4-Specific Antiviral Gene Program | Immunity | 2002 | 781 |
| 8 | Magnesium: Nature's physiologic calcium blocker | American Heart Journal | 1984 | 746 |
| 9 | Utility of B-Natriuretic Peptide in Detecting Diastolic Dysfunction | Circulation | 2002 | 734 |
| 10 | Epigenomic Analysis of Multilineage Differentiation of Human Embryonic Stem Cells | Cell | 2013 | 689 |
| 11 | A laser-engraved wearable sensor for sensitive detection of uric acid and tyrosine in sweat | Nature Biotechnology | 2020 | 683 |
| 12 | Heart Failure With Preserved, Borderline, and Reduced Ejection Fraction | Journal of the American College of Cardiology | 2017 | 671 |
| 13 | Randomized Comparison of Percutaneous Repair and Surgery for Mitral Regurgitation | Journal of the American College of Cardiology | 2015 | 658 |
| 14 | Importance of heart failure with preserved systolic function in patients ≥65 years of age | American Journal of Cardiology | 2001 | 588 |
| 15 | Primary Prevention of Cardiovascular Diseases in People With Diabetes Mellitus: A scientific statement from the American Heart Association and the American Diabetes Association | Diabetes Care | 2007 | 577 |
| 16 | Progression of Atherosclerosis as Assessed by Carotid Intima-Media Thickness in Patients With HIV Infection | Circulation | 2004 | 552 |
| 17 | Multi-ethnic genome-wide association study for atrial fibrillation | Nature Genetics | 2018 | 552 |
| 18 | Differential effects of prostaglandin derived from -6 and -3 polyunsaturated fatty acids on COX-2 expression and IL-6 secretion | Proceedings of the National Academy of Sciences of the United States of America | 2003 | 546 |
| 19 | Utility of a rapid B-natriuretic peptide assay in differentiating congestive heart failure from lung disease in patients presenting with dyspnea | Journal of the American College of Cardiology | 2002 | 530 |
| 20 | A simple method for noninvasive estimation of pulmonary vascular resistance | Journal of the American College of Cardiology | 2003 | 525 |
| 21 | The knockout of miR-143 and -145 alters smooth muscle cell maintenance and vascular homeostasis in mice: correlates with human disease | Cell Death and Differentiation | 2009 | 504 |
| 22 | Predictive value of systolic and diastolic function for incident congestive heart failure in the elderly: The Cardiovascular Health Study | Journal of the American College of Cardiology | 2001 | 477 |
| 23 | Door-to-Needle Times for Tissue Plasminogen Activator Administration and Clinical Outcomes in Acute Ischemic Stroke Before and After a Quality Improvement Initiative | JAMA - Journal of the American Medical Association | 2014 | 469 |
| 24 | Reduced incidence of admissions for myocardial infarction associated with public smoking ban: before and after study | BMJ: British Medical Journal | 2004 | 437 |
| 25 | Diagnostic value of transesophageal compared with transthoracic echocardiography in infective endocarditis | Journal of the American College of Cardiology | 1991 | 431 |
| 26 | Normal high density lipoprotein inhibits three steps in the formation of mildly oxidized low density lipoprotein: step 1 | Journal of Lipid Research | 2000 | 423 |
| 27 | γ-Butyrobetaine Is a Proatherogenic Intermediate in Gut Microbial Metabolism of L-Carnitine to TMAO | Cell Metabolism | 2014 | 416 |
| 28 | A Mouse Model of Mitochondrial Disease Reveals Germline Selection Against Severe mtDNA Mutations | Science | 2008 | 408 |
| 29 | Coronary artery calcium evaluation by electron beam computed tomography and its relation to new cardiovascular events | American Journal of Cardiology | 2000 | 404 |
| 30 | Calcification in atherosclerosis: Bone biology and chronic inflammation at the arterial crossroads | Proceedings of the National Academy of Sciences of the United States of America | 2003 | 393 |
| 31 | Real-Time Ultrasound Guidance Facilitates Femoral Arterial Access and Reduces Vascular Complications | JACC: Cardiovascular Interventions | 2010 | 386 |
| 32 | Estimating lifetime benefits of comprehensive disease-modifying pharmacological therapies in patients with heart failure with reduced ejection fraction: a comparative analysis of three randomised controlled trials | Lancet, The | 2020 | 376 |
| 33 | M-Mode echocardiographic predictors of six- to seven-year incidence of coronary heart disease, stroke, congestive heart failure, and mortality in an elderly cohort (the cardiovascular health study) | American Journal of Cardiology | 2001 | 367 |
| 34 | Epidemiology of Diabetes Mellitus and Cardiovascular Disease | Current Cardiology Reports | 2019 | 363 |
| 35 | Passive Detection of Atrial Fibrillation Using a Commercially Available Smartwatch | JAMA Cardiology | 2018 | 357 |
| 36 | Normal high density lipoprotein inhibits three steps in the formation of mildly oxidized low density lipoprotein: steps 2 and 3 | Journal of Lipid Research | 2000 | 353 |
| 37 | Diabetes mellitus is a strong, independent risk for atrial fibrillation and flutter in addition to other cardiovascular disease | International Journal of Cardiology | 2005 | 341 |
| 38 | Utility of B-natriuretic peptide as a rapid, point-of-care test for screening patients undergoing echocardiography to determine left ventricular dysfunction | American Heart Journal | 2001 | 336 |
| 39 | Evaluation of pulmonary artery pressure and resistance by pulsed Doppler echocardiography | American Journal of Cardiology | 1987 | 331 |
| 40 | Particulate matter and atherosclerosis: role of particle size, composition and oxidative stress | Particle and Fibre Toxicology | 2009 | 328 |
| 41 | Oral D-4F Causes Formation of Pre-β High-Density Lipoprotein and Improves High-Density Lipoprotein–Mediated Cholesterol Efflux and Reverse Cholesterol Transport From Macrophages in Apolipoprotein E–Null Mice | Circulation | 2004 | 325 |
| 42 | Morphological effects of coronary balloon angioplasty in vivo assessed by intravascular ultrasound imaging. | Circulation | 1992 | 324 |
| 43 | Normal high density lipoprotein inhibits three steps in the formation of mildly oxidized low density lipoprotein: steps 2 and 3 | Journal of Lipid Research | 2000 | 324 |
| 44 | Limiting Cholesterol Biosynthetic Flux Spontaneously Engages Type I IFN Signaling | Cell | 2015 | 322 |
| 45 | Human Paraoxonase-3 Is an HDL-Associated Enzyme With Biological Activity Similar to Paraoxonase-1 Protein but Is Not Regulated by Oxidized Lipids | Arteriosclerosis, Thrombosis, and Vascular Biology | 2001 | 319 |
| 46 | Ventricular contraction abnormalities in dilated cardiomyopathy: effect of biventricular pacing to correct interventricular dyssynchrony | Journal of the American College of Cardiology | 2000 | 315 |
| 47 | Dynamic changes in left ventricular wall thickness and their use in analyzing cardiac function in the conscious dog | American Journal of Cardiology | 1976 | 311 |
| 48 | Position paper Statin intolerance – an attempt at a unified definition. Position paper from an International Lipid Expert Panel | Archives of Medical Science | 2015 | 311 |
| 49 | Apoptotic Cells with Oxidation-specific Epitopes Are Immunogenic and Proinflammatory | Journal of Experimental Medicine | 2004 | 310 |
| 50 | Interactions between Roseburia intestinalis and diet modulate atherogenesis in a murine model | Nature Microbiology | 2018 | 310 |
