| # | Title | Journal | Year | Citations |
|---|
| 1 | Guidelines for the use of flow cytometry and cell sorting in immunological studies* | European Journal of Immunology | 2017 | 505 |
| 2 | M2 Macrophage-Derived Exosomes Promote Cell Migration and Invasion in Colon Cancer | Cancer Research | 2019 | 446 |
| 3 | Clinical characteristics and risk factors associated with COVID-19 disease severity in patients with cancer in Wuhan, China: a multicentre, retrospective, cohort study | Lancet Oncology, The | 2020 | 421 |
| 4 | Delivery of chemotherapeutic drugs in tumour cell-derived microparticles | Nature Communications | 2012 | 387 |
| 5 | IL-17-Producing Alveolar Macrophages Mediate Allergic Lung Inflammation Related to Asthma | Journal of Immunology | 2008 | 265 |
| 6 | miR‐142‐3p restricts cAMP production in CD4+CD25− T cells and CD4+CD25+ TREG cells by targeting AC9 mRNA | EMBO Reports | 2009 | 243 |
| 7 | A comparison study of SARS‐CoV‐2 IgG antibody between male and female COVID‐19 patients: A possible reason underlying different outcome between sex | Journal of Medical Virology | 2020 | 230 |
| 8 | Interleukin-33 Ameliorates Experimental Colitis through Promoting Th2/Foxp3+ Regulatory T-Cell Responses in Mice | Molecular Medicine | 2012 | 162 |
| 9 | Matrix softness regulates plasticity of tumour-repopulating cells via H3K9 demethylation and Sox2 expression | Nature Communications | 2014 | 162 |
| 10 | MicroRNA-21 is involved in osteosarcoma cell invasion and migration | Medical Oncology | 2011 | 161 |
| 11 | Selenium–GPX4 axis protects follicular helper T cells from ferroptosis | Nature Immunology | 2021 | 158 |
| 12 | Transmembrane TNF-α Promotes Suppressive Activities of Myeloid-Derived Suppressor Cells via TNFR2 | Journal of Immunology | 2014 | 148 |
| 13 | Mast Cells Mobilize Myeloid-Derived Suppressor Cells and Treg Cells in Tumor Microenvironment via IL-17 Pathway in Murine Hepatocarcinoma Model | PLoS ONE | 2010 | 145 |
| 14 | CD14: Biology and role in the pathogenesis of disease | Cytokine and Growth Factor Reviews | 2019 | 141 |
| 15 | Lactate inhibits ATP6V0d2 expression in tumor-associated macrophages to promote HIF-2α–mediated tumor progression | Journal of Clinical Investigation | 2019 | 138 |
| 16 | Extracellular Hmgb1 Functions as an Innate Immune-Mediator Implicated in Murine Cardiac Allograft Acute Rejection | American Journal of Transplantation | 2007 | 137 |
| 17 | Liposomes-coated gold nanocages with antigens and adjuvants targeted delivery to dendritic cells for enhancing antitumor immune response | Biomaterials | 2017 | 133 |
| 18 | Lactate in the tumour microenvironment: From immune modulation to therapy | EBioMedicine | 2021 | 132 |
| 19 | EZH2 is crucial for both differentiation of regulatory T cells and T effector cell expansion | Scientific Reports | 2015 | 129 |
| 20 | Erythropoietin prevents PC12 cells from 1-methyl-4-phenylpyridinium ion-induced apoptosis via the Akt/GSK-3β/caspase-3 mediated signaling pathway | Apoptosis: an International Journal on Programmed Cell Death | 2007 | 118 |
| 21 | Gene Silencing of NALP3 Protects Against Liver Ischemia–Reperfusion Injury in Mice | Human Gene Therapy | 2011 | 117 |
| 22 | Glycogen metabolism regulates macrophage-mediated acute inflammatory responses | Nature Communications | 2020 | 114 |
| 23 | Interferon-γ induces tumor resistance to anti-PD-1 immunotherapy by promoting YAP phase separation | Molecular Cell | 2021 | 114 |
| 24 | Late-stage tumors induce anemia and immunosuppressive extramedullary erythroid progenitor cells | Nature Medicine | 2018 | 112 |
| 25 | Ketogenesis-generated β-hydroxybutyrate is an epigenetic regulator of CD8+ T-cell memory development | Nature Cell Biology | 2020 | 104 |
| 26 | Extracellular High-Mobility Group Box 1 Acts as an Innate Immune Mediator to Enhance Autoimmune Progression and Diabetes Onset in NOD Mice | Diabetes | 2008 | 101 |
| 27 | The macrophage-specific V-ATPase subunit ATP6V0D2 restricts inflammasome activation and bacterial infection by facilitating autophagosome-lysosome fusion | Autophagy | 2019 | 101 |
| 28 | 14, 15-EET induces breast cancer cell EMT and cisplatin resistance by up-regulating integrin αvβ3 and activating FAK/PI3K/AKT signaling | Journal of Experimental and Clinical Cancer Research | 2018 | 99 |
| 29 | Fabrication of Stable and RNase-Resistant RNA Nanoparticles Active in Gearing the Nanomotors for Viral DNA Packaging | ACS Nano | 2011 | 95 |
| 30 | Neutralization of the extracellular HMGB1 released by ischaemic-damaged renal cells protects against renal ischaemia-reperfusion injury | Nephrology Dialysis Transplantation | 2011 | 95 |
| 31 | Interleukin-33 ameliorates ischemic brain injury in experimental stroke through promoting Th2 response and suppressing Th17 response | Brain Research | 2015 | 95 |
| 32 | Recent advances in targeted nanoparticles drug delivery to melanoma | Nanomedicine: Nanotechnology, Biology, and Medicine | 2015 | 94 |
| 33 | Immune modulation of liver sinusoidal endothelial cells by melittin nanoparticles suppresses liver metastasis | Nature Communications | 2019 | 93 |
| 34 | IL-33 accelerates cutaneous wound healing involved in upregulation of alternatively activated macrophages | Molecular Immunology | 2013 | 88 |
| 35 | miR-7 reverses the resistance to BRAFi in melanoma by targeting EGFR/IGF-1R/CRAF and inhibiting the MAPK and PI3K/AKT signaling pathways | Oncotarget | 2016 | 86 |
| 36 | Cytotoxicity of BSA-Stabilized Gold Nanoclusters: In Vitro and In Vivo Study | Small | 2015 | 85 |
| 37 | Tumor cell-derived microparticles polarize M2 tumor-associated macrophages for tumor progression | OncoImmunology | 2016 | 85 |
| 38 | Targeting Transmembrane TNF-α Suppresses Breast Cancer Growth | Cancer Research | 2013 | 82 |
| 39 | Curcumin induces apoptosis and protective autophagy in castration-resistant prostate cancer cells through iron chelation | Drug Design, Development and Therapy | 2017 | 82 |
| 40 | Polyethylenimine-based micro/nanoparticles as vaccine adjuvants | International Journal of Nanomedicine | 2017 | 78 |
| 41 | Resistance to chemotherapy-induced apoptosis via decreased caspase-3 activity and overexpression of antiapoptotic proteins in ovarian cancer | Journal of Cancer Research and Clinical Oncology | 2004 | 76 |
| 42 | Blockade of Tumor Necrosis Factor (TNF) Receptor Type 1-Mediated TNF-α Signaling Protected Wistar Rats from Diet-Induced Obesity and Insulin Resistance | Endocrinology | 2008 | 74 |
| 43 | Interleukin-7 Biology and Its Effects on Immune Cells: Mediator of Generation, Differentiation, Survival, and Homeostasis | Frontiers in Immunology | 2021 | 73 |
| 44 | Vα24-Invariant NKT Cells from Patients with Allergic Asthma Express CCR9 at High Frequency and Induce Th2 Bias of CD3+T Cells upon CD226 Engagement | Journal of Immunology | 2005 | 72 |
| 45 | Use of bacteriophage in the treatment of experimental animal bacteremia from imipenem-resistant Pseudomonas aeruginosa | International Journal of Molecular Medicine | 2006 | 72 |
| 46 | Acid-Sensing Ion Channels Contribute to the Effect of Acidosis on the Function of Dendritic Cells | Journal of Immunology | 2011 | 70 |
| 47 | Genome-Wide Analysis of DNA Methylation and Acute Coronary Syndrome | Circulation Research | 2017 | 70 |
| 48 | High-mobility group box 1 promotes early acute allograft rejection by enhancing IL-6-dependent Th17 alloreactive response | Laboratory Investigation | 2011 | 69 |
| 49 | The Transcription Factor TCF1 Preserves the Effector Function of Exhausted CD8 T Cells During Chronic Viral Infection | Frontiers in Immunology | 2019 | 66 |
| 50 | Heme oxygenase-1 upregulation significantly inhibits TNF-α and Hmgb1 releasing and attenuates lipopolysaccharide-induced acute lung injury in mice | International Immunopharmacology | 2008 | 64 |
