# | Title | Journal | Year | Citations |
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1 | Toxic Potential of Materials at the Nanolevel | Science | 2006 | 7,944 |
2 | Metascape provides a biologist-oriented resource for the analysis of systems-level datasets | Nature Communications | 2019 | 7,886 |
3 | The Cancer Genome Atlas Pan-Cancer analysis project | Nature Genetics | 2013 | 6,265 |
4 | The Acute Respiratory Distress Syndrome | New England Journal of Medicine | 2000 | 5,867 |
5 | Acute renal failure - definition, outcome measures, animal models, fluid therapy and information technology needs: the Second International Consensus Conference of the Acute Dialysis Quality Initiative (ADQI) Group | Critical Care | 2004 | 5,531 |
6 | Atherosclerosis | Nature | 2000 | 4,551 |
7 | Cancer immunotherapy using checkpoint blockade | Science | 2018 | 4,274 |
8 | Cytoscape 2.8: new features for data integration and network visualization | Bioinformatics | 2011 | 4,228 |
9 | Hepcidin Regulates Cellular Iron Efflux by Binding to Ferroportin and Inducing Its Internalization | Science | 2004 | 4,042 |
10 | Derivation and Prospective Validation of a Simple Index for Prediction of Cardiac Risk of Major Noncardiac Surgery | Circulation | 1999 | 3,784 |
11 | The Immune Landscape of Cancer | Immunity | 2018 | 3,706 |
12 | The Patient-Reported Outcomes Measurement Information System (PROMIS) developed and tested its first wave of adult self-reported health outcome item banks: 2005–2008 | Journal of Clinical Epidemiology | 2010 | 3,521 |
13 | The peroxisome proliferator-activated receptor-γ is a negative regulator of macrophage activation | Nature | 1998 | 3,419 |
14 | The TNF and TNF Receptor Superfamilies | Cell | 2001 | 3,271 |
15 | Targets of T Cell Responses to SARS-CoV-2 Coronavirus in Humans with COVID-19 Disease and Unexposed Individuals | Cell | 2020 | 3,220 |
16 | Guidelines for the use and interpretation of assays for monitoring autophagy | Autophagy | 2012 | 3,122 |
17 | Average Risks of Breast and Ovarian Cancer Associated with BRCA1 or BRCA2 Mutations Detected in Case Series Unselected for Family History: A Combined Analysis of 22 Studies | American Journal of Human Genetics | 2003 | 3,105 |
18 | Epidemiology and outcomes of osteoporotic fractures | Lancet, The | 2002 | 3,086 |
19 | Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation | Cell | 1991 | 3,020 |
20 | Clinical Resistance to STI-571 Cancer Therapy Caused by BCR-ABL Gene Mutation or Amplification | Science | 2001 | 2,936 |
21 | AASLD guidelines for the treatment of hepatocellular carcinoma | Hepatology | 2018 | 2,932 |
22 | Mechanisms Underlying Inflammation in Neurodegeneration | Cell | 2010 | 2,860 |
23 | RDP4: Detection and analysis of recombination patterns in virus genomes | Virus Evolution | 2015 | 2,621 |
24 | Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis | Nature Cell Biology | 2000 | 2,487 |
25 | Role of oxidized low density lipoprotein in atherogenesis. | Journal of Clinical Investigation | 1991 | 2,453 |
26 | Genomic and Transcriptomic Features of Response to Anti-PD-1 Therapy in Metastatic Melanoma | Cell | 2016 | 2,437 |
27 | The cardiovascular health study: Design and rationale | Annals of Epidemiology | 1991 | 2,407 |
28 | CRISPR-Cas12a target binding unleashes indiscriminate single-stranded DNase activity | Science | 2018 | 2,355 |
29 | Nivolumab versus chemotherapy in patients with advanced melanoma who progressed after anti-CTLA-4 treatment (CheckMate 037): a randomised, controlled, open-label, phase 3 trial | Lancet Oncology, The | 2015 | 2,353 |
30 | Reference-based analysis of lung single-cell sequencing reveals a transitional profibrotic macrophage | Nature Immunology | 2019 | 2,330 |
31 | Human insulin receptor and its relationship to the tyrosine kinase family of oncogenes | Nature | 1985 | 2,312 |
32 | CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells | Journal of Experimental Medicine | 2006 | 2,292 |
33 | Macrophages, Inflammation, and Insulin Resistance | Annual Review of Physiology | 2010 | 2,279 |
34 | IKKβ Links Inflammation and Tumorigenesis in a Mouse Model of Colitis-Associated Cancer | Cell | 2004 | 2,277 |
35 | Immunological memory to SARS-CoV-2 assessed for up to 8 months after infection | Science | 2021 | 2,268 |
36 | The Many Roles of Chemokines and Chemokine Receptors in Inflammation | New England Journal of Medicine | 2006 | 2,207 |
37 | ACMG recommendations for reporting of incidental findings in clinical exome and genome sequencing | Genetics in Medicine | 2013 | 2,186 |
38 | Comparison of the Mechanism of Toxicity of Zinc Oxide and Cerium Oxide Nanoparticles Based on Dissolution and Oxidative Stress Properties | ACS Nano | 2008 | 2,145 |
39 | Signal transduction by lymphocyte antigen receptors | Cell | 1994 | 2,108 |
40 | Natriuretic Peptides | New England Journal of Medicine | 1998 | 2,083 |
41 | Recovery of Replication-Competent HIV Despite Prolonged Suppression of Plasma Viremia | Science | 1997 | 2,071 |
42 | Waves of resistance: Staphylococcus aureus in the antibiotic era | Nature Reviews Microbiology | 2009 | 2,049 |
43 | GPR120 Is an Omega-3 Fatty Acid Receptor Mediating Potent Anti-inflammatory and Insulin-Sensitizing Effects | Cell | 2010 | 2,013 |
44 | The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor | Science | 1992 | 1,974 |
45 | Liver transplantation for hepatocellular carcinoma: Expansion of the tumor size limits does not adversely impact survival | Hepatology | 2001 | 1,931 |
46 | Best Practices for Developing and Validating Scales for Health, Social, and Behavioral Research: A Primer | Frontiers in Public Health | 2018 | 1,869 |
47 | A Mechanism for Regulating Pulmonary Inflammation and Fibrosis: The Integrin αvβ6 Binds and Activates Latent TGF β1 | Cell | 1999 | 1,867 |
48 | HIF-1α Is Essential for Myeloid Cell-Mediated Inflammation | Cell | 2003 | 1,862 |
49 | IL-6 and Stat3 Are Required for Survival of Intestinal Epithelial Cells and Development of Colitis-Associated Cancer | Cancer Cell | 2009 | 1,851 |
50 | Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-γ | Nature | 1998 | 1,818 |