| The acute respiratory distress syndrome | New England Journal of Medicine | 2000 | 5.2K |
| Atherosclerosis | Nature | 2000 | 4K |
| Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis | Nature Cell Biology | 2000 | 2.2K |
| The coregulator exchange in transcriptional functions of nuclear receptors | Genes and Development | 2000 | 1.6K |
| The neural mechanisms of top-down attentional control | Nature Neuroscience | 2000 | 1.4K |
| Aquaporin-4 deletion in mice reduces brain edema after acute water intoxication and ischemic stroke | Nature Medicine | 2000 | 1.2K |
| The way things move: looking under the hood of molecular motor proteins | Science | 2000 | 1.2K |
| Self-reported adherence to antiretroviral medications among participants in HIV clinical trials: the AACTG adherence instruments. Patient Care Committee & Adherence Working Group of the Outcomes Committee of the Adult AIDS Clinical Trials Group (AACTG) | AIDS Care - Psychological and Socio-Medical Aspects of AIDS/HIV | 2000 | 1.2K |
| TIMI risk score for ST-elevation myocardial infarction: A convenient, bedside, clinical score for risk assessment at presentation: An intravenous nPA for treatment of infarcting myocardium early II trial substudy | Circulation | 2000 | 1.1K |
| T2Rs function as bitter taste receptors | Cell | 2000 | 1.1K |
| The expanding superfamily of phospholipase A(2) enzymes: classification and characterization | Biochimica Et Biophysica Acta - Molecular and Cell Biology of Lipids | 2000 | 1K |
| Validity of a set of clinical criteria to rule out injury to the cervical spine in patients with blunt trauma. National Emergency X-Radiography Utilization Study Group | New England Journal of Medicine | 2000 | 993 |
| High mobility of proteins in the mammalian cell nucleus | Nature | 2000 | 984 |
| Astrocyte glutamate transport: Review of properties, regulation, and physiological functions | Glia | 2000 | 927 |
| Matrix metalloproteinases: effectors of development and normal physiology | Genes and Development | 2000 | 891 |
| The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription | Proceedings of the National Academy of Sciences of the United States of America | 2000 | 870 |
| Structure of a glycerol-conducting channel and the basis for its selectivity | Science | 2000 | 868 |
| Secretion of microbicidal alpha-defensins by intestinal Paneth cells in response to bacteria | Nature Immunology | 2000 | 826 |
| Fatigue in breast cancer survivors: occurrence, correlates, and impact on quality of life | Journal of Clinical Oncology | 2000 | 814 |
| Agonists of proteinase-activated receptor 2 induce inflammation by a neurogenic mechanism | Nature Medicine | 2000 | 788 |
| Adverse cardiovascular and central nervous system events associated with dietary supplements containing ephedra alkaloids | New England Journal of Medicine | 2000 | 770 |
| Functional and clinical significance of skeletal muscle architecture | Muscle and Nerve | 2000 | 740 |
| Biochemistry, mutagenesis, and oligomerization of DsRed, a red fluorescent protein from coral | Proceedings of the National Academy of Sciences of the United States of America | 2000 | 735 |
| Gender differences in the utilization of health care services | Journal of Family Practice | 2000 | 716 |
| Structure and function of a human TAFII250 double bromodomain module | Science | 2000 | 704 |
