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Top Articles

#TitleJournalYearCitations
1Toxic Potential of Materials at the NanolevelScience20067,944
2Metascape provides a biologist-oriented resource for the analysis of systems-level datasetsNature Communications20197,886
3The Cancer Genome Atlas Pan-Cancer analysis projectNature Genetics20136,265
4The Acute Respiratory Distress SyndromeNew England Journal of Medicine20005,867
5Acute renal failure - definition, outcome measures, animal models, fluid therapy and information technology needs: the Second International Consensus Conference of the Acute Dialysis Quality Initiative (ADQI) GroupCritical Care20045,531
6AtherosclerosisNature20004,551
7Cancer immunotherapy using checkpoint blockadeScience20184,274
8Cytoscape 2.8: new features for data integration and network visualizationBioinformatics20114,228
9Hepcidin Regulates Cellular Iron Efflux by Binding to Ferroportin and Inducing Its InternalizationScience20044,042
10Derivation and Prospective Validation of a Simple Index for Prediction of Cardiac Risk of Major Noncardiac SurgeryCirculation19993,784
11The Immune Landscape of CancerImmunity20183,706
12The Patient-Reported Outcomes Measurement Information System (PROMIS) developed and tested its first wave of adult self-reported health outcome item banks: 2005–2008Journal of Clinical Epidemiology20103,521
13The peroxisome proliferator-activated receptor-γ is a negative regulator of macrophage activationNature19983,419
14The TNF and TNF Receptor SuperfamiliesCell20013,271
15Targets of T Cell Responses to SARS-CoV-2 Coronavirus in Humans with COVID-19 Disease and Unexposed IndividualsCell20203,220
16Guidelines for the use and interpretation of assays for monitoring autophagyAutophagy20123,122
17Average Risks of Breast and Ovarian Cancer Associated with BRCA1 or BRCA2 Mutations Detected in Case Series Unselected for Family History: A Combined Analysis of 22 StudiesAmerican Journal of Human Genetics20033,105
18Epidemiology and outcomes of osteoporotic fracturesLancet, The20023,086
19Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activationCell19913,020
20Clinical Resistance to STI-571 Cancer Therapy Caused by BCR-ABL Gene Mutation or AmplificationScience20012,936
21AASLD guidelines for the treatment of hepatocellular carcinomaHepatology20182,932
22Mechanisms Underlying Inflammation in NeurodegenerationCell20102,860
23RDP4: Detection and analysis of recombination patterns in virus genomesVirus Evolution20152,621
24Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesisNature Cell Biology20002,487
25Role of oxidized low density lipoprotein in atherogenesis.Journal of Clinical Investigation19912,453
26Genomic and Transcriptomic Features of Response to Anti-PD-1 Therapy in Metastatic MelanomaCell20162,437
27The cardiovascular health study: Design and rationaleAnnals of Epidemiology19912,407
28CRISPR-Cas12a target binding unleashes indiscriminate single-stranded DNase activityScience20182,355
29Nivolumab versus chemotherapy in patients with advanced melanoma who progressed after anti-CTLA-4 treatment (CheckMate 037): a randomised, controlled, open-label, phase 3 trialLancet Oncology, The20152,353
30Reference-based analysis of lung single-cell sequencing reveals a transitional profibrotic macrophageNature Immunology20192,330
31Human insulin receptor and its relationship to the tyrosine kinase family of oncogenesNature19852,312
32CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cellsJournal of Experimental Medicine20062,292
33Macrophages, Inflammation, and Insulin ResistanceAnnual Review of Physiology20102,279
34IKKβ Links Inflammation and Tumorigenesis in a Mouse Model of Colitis-Associated CancerCell20042,277
35Immunological memory to SARS-CoV-2 assessed for up to 8 months after infectionScience20212,268
36The Many Roles of Chemokines and Chemokine Receptors in InflammationNew England Journal of Medicine20062,207
37ACMG recommendations for reporting of incidental findings in clinical exome and genome sequencingGenetics in Medicine20132,186
38Comparison of the Mechanism of Toxicity of Zinc Oxide and Cerium Oxide Nanoparticles Based on Dissolution and Oxidative Stress PropertiesACS Nano20082,145
39Signal transduction by lymphocyte antigen receptorsCell19942,108
40Natriuretic PeptidesNew England Journal of Medicine19982,083
41Recovery of Replication-Competent HIV Despite Prolonged Suppression of Plasma ViremiaScience19972,071
42Waves of resistance: Staphylococcus aureus in the antibiotic eraNature Reviews Microbiology20092,049
43GPR120 Is an Omega-3 Fatty Acid Receptor Mediating Potent Anti-inflammatory and Insulin-Sensitizing EffectsCell20102,013
44The fms-like tyrosine kinase, a receptor for vascular endothelial growth factorScience19921,974
45Liver transplantation for hepatocellular carcinoma: Expansion of the tumor size limits does not adversely impact survivalHepatology20011,931
46Best Practices for Developing and Validating Scales for Health, Social, and Behavioral Research: A PrimerFrontiers in Public Health20181,869
47A Mechanism for Regulating Pulmonary Inflammation and Fibrosis: The Integrin αvβ6 Binds and Activates Latent TGF β1Cell19991,867
48HIF-1α Is Essential for Myeloid Cell-Mediated InflammationCell20031,862
49IL-6 and Stat3 Are Required for Survival of Intestinal Epithelial Cells and Development of Colitis-Associated CancerCancer Cell20091,851
50Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-γNature19981,818