| # | Title | Journal | Year | Citations |
|---|
| 1 | Tumor Angiogenesis | New England Journal of Medicine | 2008 | 1,996 |
| 2 | The Genome of the Sea Urchin Strongylocentrotus purpuratus | Science | 2006 | 1,018 |
| 3 | The ctenophore genome and the evolutionary origins of neural systems | Nature | 2014 | 606 |
| 4 | The immune gene repertoire encoded in the purple sea urchin genome | Developmental Biology | 2006 | 513 |
| 5 | Improving immunotherapy outcomes with anti-angiogenic treatments and vice versa | Nature Reviews Clinical Oncology | 2018 | 412 |
| 6 | Genomic Insights into the Immune System of the Sea Urchin | Science | 2006 | 384 |
| 7 | Drug rechallenge and treatment beyond progression—implications for drug resistance | Nature Reviews Clinical Oncology | 2013 | 219 |
| 8 | Guidelines and Good Clinical Practice Recommendations for Contrast-Enhanced Ultrasound (CEUS) in the Liver–Update 2020 WFUMB in Cooperation with EFSUMB, AFSUMB, AIUM, and FLAUS | Ultrasound in Medicine and Biology | 2020 | 210 |
| 9 | Glypican-3 binds to frizzled and plays a direct role in the stimulation of canonical Wnt signaling | Journal of Cell Science | 2014 | 146 |
| 10 | Glypican-5 stimulates rhabdomyosarcoma cell proliferation by activating Hedgehog signaling | Journal of Cell Biology | 2011 | 130 |
| 11 | The synthetic Tie2 agonist peptide vasculotide protects against vascular leakage and reduces mortality in murine abdominal sepsis | Critical Care | 2011 | 114 |
| 12 | Brainstem blood brain barrier disruption using focused ultrasound: A demonstration of feasibility and enhanced doxorubicin delivery | Journal of Controlled Release | 2018 | 99 |
| 13 | Insights into the key roles of proteoglycans in breast cancer biology and translational medicine | Biochimica Et Biophysica Acta: Reviews on Cancer | 2015 | 96 |
| 14 | Effects of a synthetic PEG-ylated Tie-2 agonist peptide on endotoxemic lung injury and mortality | American Journal of Physiology - Lung Cellular and Molecular Physiology | 2011 | 88 |
| 15 | White matter microstructure in athletes with a history of concussion: Comparing diffusion tensor imaging (DTI) and neurite orientation dispersion and density imaging (NODDI) | Human Brain Mapping | 2017 | 82 |
| 16 | Perturbation of gut bacteria induces a coordinated cellular immune response in the purple sea urchin larva | Immunology and Cell Biology | 2016 | 78 |
| 17 | PPARα and fatty acid oxidation mediate glucocorticoid resistance in chronic lymphocytic leukemia | Blood | 2013 | 77 |
| 18 | PLEKHA5 as a Biomarker and Potential Mediator of Melanoma Brain Metastasis | Clinical Cancer Research | 2015 | 71 |
| 19 | Ultrasound enhanced drug delivery to the brain and central nervous system | International Journal of Hyperthermia | 2012 | 69 |
| 20 | An ancient role for Gata-1/2/3 and Scl transcription factor homologs in the development of immunocytes | Developmental Biology | 2013 | 69 |
| 21 | Early‐stage attenuation of phase‐amplitude coupling in the hippocampus and medial prefrontal cortex in a transgenic rat model of Alzheimer's disease | Journal of Neurochemistry | 2018 | 69 |
| 22 | Blood‐Brain Barrier Closure Time After Controlled Ultrasound‐Induced Opening Is Independent of Opening Volume | Journal of Ultrasound in Medicine | 2017 | 65 |
| 23 | The relevance of skull density ratio in selecting candidates for transcranial MR-guided focused ultrasound | Journal of Neurosurgery | 2020 | 62 |
| 24 | Roles for Endothelin Receptor B and BCL2A1 in Spontaneous CNS Metastasis of Melanoma | Cancer Research | 2012 | 61 |
| 25 | The potential clinical promise of ‘multimodality’ metronomic chemotherapy revealed by preclinical studies of metastatic disease | Cancer Letters | 2017 | 59 |
| 26 | High-Intensity Focused Ultrasound Sonothrombolysis: The Use of Perfluorocarbon Droplets to Achieve Clot Lysis at Reduced Acoustic Power | Ultrasound in Medicine and Biology | 2014 | 58 |
| 27 | Time course of focused ultrasound effects on β-amyloid plaque pathology in the TgCRND8 mouse model of Alzheimer’s disease | Scientific Reports | 2018 | 58 |
| 28 | A Decade of Experience in Developing Preclinical Models of Advanced- or Early-Stage Spontaneous Metastasis to Study Antiangiogenic Drugs, Metronomic Chemotherapy, and the Tumor Microenvironment | Cancer Journal (Sudbury, Mass ) | 2015 | 56 |
| 29 | Intracranial Applications of Magnetic Resonance-guided Focused Ultrasound | Neurotherapeutics | 2014 | 55 |
| 30 | Alternative mechanisms of immune receptor diversity | Current Opinion in Immunology | 2007 | 52 |
| 31 | Mechanisms of microbubble–vessel interactions and induced stresses: A numerical study | Journal of the Acoustical Society of America | 2013 | 52 |
| 32 | Implications of disturbances in circadian rhythms for cardiovascular health: A new frontier in free radical biology | Free Radical Biology and Medicine | 2018 | 50 |
| 33 | Noninvasive delivery of an α‐synuclein gene silencing vector with magnetic resonance–guided focused ultrasound | Movement Disorders | 2018 | 49 |
| 34 | MR-guided Focused Ultrasound Facilitates Sonodynamic Therapy with 5-Aminolevulinic Acid in a Rat Glioma Model | Scientific Reports | 2019 | 48 |
| 35 | Microbubbles and Blood–Brain Barrier Opening: A Numerical Study on Acoustic Emissions and Wall Stress Predictions | IEEE Transactions on Biomedical Engineering | 2015 | 44 |
| 36 | Comparison of analytical and numerical approaches for CT-based aberration correction in transcranial passive acoustic imaging | Physics in Medicine and Biology | 2016 | 41 |
| 37 | The Synthetic Tie2 Agonist Peptide Vasculotide Protects Renal Vascular Barrier Function In Experimental Acute Kidney Injury | Scientific Reports | 2016 | 39 |
| 38 | Low-Dose Metronomic Oral Dosing of a Prodrug of Gemcitabine (LY2334737) Causes Antitumor Effects in the Absence of Inhibition of Systemic Vasculogenesis | Molecular Cancer Therapeutics | 2012 | 38 |
| 39 | Strategies for Improving the Clinical Benefit of Antiangiogenic Drug Based Therapies for Breast Cancer | Journal of Mammary Gland Biology and Neoplasia | 2012 | 34 |
| 40 | Subharmonic, Non-linear Fundamental and Ultraharmonic Imaging of Microbubble Contrast at High Frequencies | Ultrasound in Medicine and Biology | 2015 | 29 |
| 41 | Ultrasound-sensitive nanodroplets achieve targeted neuromodulation | Journal of Controlled Release | 2021 | 29 |
| 42 | Incorporating endorectal MR elastography into multi‐parametric MRI for prostate cancer imaging: Initial feasibility in volunteers | Journal of Magnetic Resonance Imaging | 2013 | 28 |
| 43 | Processing by Convertases Is Required for Glypican-3-induced Inhibition of Hedgehog Signaling | Journal of Biological Chemistry | 2015 | 28 |
| 44 | Controlled bone formation using ultrasound-triggered release of BMP-2 from liposomes | Journal of Controlled Release | 2016 | 28 |
| 45 | Preliminary Investigation of Focused Ultrasound-Facilitated Drug Delivery for the Treatment of Leptomeningeal Metastases | Scientific Reports | 2018 | 27 |
| 46 | Tumors resurrect an embryonic vascular program to escape immunity | Science Immunology | 2022 | 27 |
| 47 | Construction of 3D MR image-based computer models of pathologic hearts, augmented with histology and optical fluorescence imaging to characterize action potential propagation | Medical Image Analysis | 2012 | 26 |
| 48 | Cavitation-based third ventriculostomy using MRI-guided focused ultrasound | Journal of Neurosurgery | 2013 | 26 |
| 49 | MR thermometry in the human prostate gland at 3.0T for transurethral ultrasound therapy | Journal of Magnetic Resonance Imaging | 2013 | 26 |
| 50 | Contrast-Enhanced Ultrasound of Focal Liver Masses: A Success Story | Ultrasound in Medicine and Biology | 2020 | 26 |
