| # | Title | Journal | Year | Citations |
|---|
| 1 | Long-term follow-up of the Medical Research Council CLASICC trial of conventional versus laparoscopically assisted resection in colorectal cancer | British Journal of Surgery | 2012 | 586 |
| 2 | Mutations in 15-hydroxyprostaglandin dehydrogenase cause primary hypertrophic osteoarthropathy | Nature Genetics | 2008 | 267 |
| 3 | Reporting colorectal cancer | Histopathology | 2007 | 186 |
| 4 | What primary microcephaly can tell us about brain growth | Trends in Molecular Medicine | 2006 | 160 |
| 5 | Differentiating drusen: Drusen and drusen-like appearances associated with ageing, age-related macular degeneration, inherited eye disease and other pathological processes | Progress in Retinal and Eye Research | 2016 | 159 |
| 6 | The proportion of tumour cells is an independent predictor for survival in colorectal cancer patients | British Journal of Cancer | 2010 | 151 |
| 7 | The role of PU.1 and GATA-1 transcription factors during normal and leukemogenic hematopoiesis | Leukemia | 2010 | 151 |
| 8 | The future of the TNM staging system in colorectal cancer: time for a debate? | Lancet Oncology, The | 2007 | 148 |
| 9 | Dichloroacetate induces apoptosis and cell-cycle arrest in colorectal cancer cells | British Journal of Cancer | 2010 | 148 |
| 10 | Ketohexokinase: Expression and Localization of the Principal Fructose-metabolizing Enzyme | Journal of Histochemistry and Cytochemistry | 2009 | 141 |
| 11 | Objective assessment of blood and lymphatic vessel invasion and association with macrophage infiltration in cutaneous melanoma | Modern Pathology | 2012 | 105 |
| 12 | MiR-26b is down-regulated in carcinoma-associated fibroblasts from ER-positive breast cancers leading to enhanced cell migration and invasion | Journal of Pathology | 2013 | 103 |
| 13 | Genetic and functional analyses demonstrate a role for abnormal glycinergic signaling in autism | Molecular Psychiatry | 2016 | 85 |
| 14 | Interleukin-7 in rheumatoid arthritis | Rheumatology | 2008 | 77 |
| 15 | Non‐invasive molecular imaging for preclinical cancer therapeutic development | British Journal of Pharmacology | 2013 | 77 |
| 16 | Post-mortem histopathology underlying β-amyloid PET imaging following flutemetamol F 18 injection | Acta Neuropathologica Communications | 2016 | 76 |
| 17 | A family with Papillon-Lefèvre syndrome reveals a requirement for cathepsin C in granzyme B activation and NK cell cytolytic activity | Blood | 2006 | 71 |
| 18 | PCRPi: Presaging Critical Residues in Protein interfaces, a new computational tool to chart hot spots in protein interfaces | Nucleic Acids Research | 2010 | 70 |
| 19 | Mechanisms of FGFR3 actions in endocrine resistant breast cancer | International Journal of Cancer | 2012 | 69 |
| 20 | Prostaglandin E2-EP4 receptor signalling promotes tumorigenic behaviour of HT-29 human colorectal cancer cells | Oncogene | 2007 | 63 |
| 21 | Uses of the in vitro endothelial–fibroblast organotypic co-culture assay in angiogenesis research | Biochemical Society Transactions | 2011 | 61 |
| 22 | Interfering with RAS–effector protein interactions prevent RAS-dependent tumour initiation and causes stop–start control of cancer growth | Oncogene | 2010 | 59 |
| 23 | Stem cell–specific epigenetic priming and B cell–specific transcriptional activation at the mouse Cd19 locus | Blood | 2008 | 58 |
| 24 | Guidelines and considerations for conducting experiments using tissue microarrays | Histopathology | 2013 | 57 |
| 25 | Extensive gene conversion at thePMS2DNA mismatch repair locus | Human Mutation | 2007 | 56 |
| 26 | Dissection of the FCGR3A association with RA: increased association in men and with autoantibody positive disease | Annals of the Rheumatic Diseases | 2010 | 55 |
| 27 | Dietary, lifestyle and clinicopathological factors associated with APC mutations and promoter methylation in colorectal cancers from the EPIC‐Norfolk study | Journal of Pathology | 2012 | 51 |
| 28 | Diagnosis of copy number variation by Illumina next generation sequencing is comparable in performance to oligonucleotide array comparative genomic hybridisation | Genomics | 2013 | 48 |
| 29 | Common and recurrent HPGD mutations in Caucasian individuals with primary hypertrophic osteoarthropathy | Rheumatology | 2010 | 47 |
| 30 | Flow cytometric characterization of freshly isolated and culture expanded human synovial cell populations in patients with chronic arthritis | Arthritis Research and Therapy | 2010 | 46 |
| 31 | Both isoforms of ketohexokinase are dispensable for normal growth and development | Physiological Genomics | 2010 | 45 |
| 32 | Polymorphisms in xenobiotic metabolizing enzymes and diet influence colorectal adenoma risk | Pharmacogenetics and Genomics | 2010 | 42 |
| 33 | Population-based study of laparoscopic colorectal cancer surgery 2006–2008 | British Journal of Surgery | 2013 | 37 |
| 34 | Tumour‐promoting activity of altered WWP1 expression in breast cancer and its utility as a prognostic indicator | Journal of Pathology | 2008 | 35 |
| 35 | Runx1 binds as a dimeric complex to overlapping Runx1 sites within a palindromic element in the human GM-CSF enhancer | Nucleic Acids Research | 2010 | 35 |
| 36 | Virtual reality microscope versus conventional microscope regarding time to diagnosis: an experimental study | Histopathology | 2013 | 34 |
| 37 | Post-transcriptional regulation of gene expression by alternative 5′-untranslated regions in carcinogenesis | Biochemical Society Transactions | 2008 | 32 |
| 38 | Decreased Levels of the RNA Splicing Factor Prpf3 in Mice and Zebrafish Do Not Cause Photoreceptor Degeneration | | 2008 | 31 |
| 39 | CCAAT/enhancer binding protein α, β and δ gene variants: associations with obesity related phenotypes in the Leeds Family Study | Diabetes and Vascular Disease Research | 2010 | 28 |
| 40 | The Human IL-3/Granulocyte-Macrophage Colony-Stimulating Factor Locus Is Epigenetically Silent in Immature Thymocytes and Is Progressively Activated during T Cell Development | Journal of Immunology | 2010 | 28 |
| 41 | Transcription-dependent silencing of inducible convergent transgenes in transgenic mice | Epigenetics and Chromatin | 2010 | 27 |
| 42 | RUNX1 regulates theCD34gene in haematopoietic stem cells by mediating interactions with a distal regulatory element | EMBO Journal | 2011 | 26 |
| 43 | Comparison of treatment and outcome information between a clinical trial and the National Cancer Data Repository | British Journal of Surgery | 2010 | 25 |
| 44 | ABT-263 Enhances Sensitivity to Metformin and 2-Deoxyglucose in Pediatric Glioma by Promoting Apoptotic Cell Death | PLoS ONE | 2013 | 24 |
| 45 | The potential role of ERβ isoforms in the clinical management of breast cancer | Histopathology | 2008 | 22 |
| 46 | Chromatin regulation by RUNX1 | Blood Cells, Molecules, and Diseases | 2010 | 22 |
| 47 | Adenovirus-mediated hypoxia-targeted gene therapy using HSV thymidine kinase and bacterial nitroreductase prodrug-activating genes in vitro and in vivo | Cancer Gene Therapy | 2011 | 20 |
| 48 | Revised Staging: Is It Really Better, or Do We Not Know? | Journal of Clinical Oncology | 2010 | 18 |
| 49 | Genomic evidence of pre‐invasive clonal expansion, dispersal and progression in bronchial dysplasia | Journal of Pathology | 2011 | 18 |
| 50 | Evaluation of splicing efficiency in lymphoblastoid cell lines from patients with splicing-factor retinitis pigmentosa | Molecular Vision | 2008 | 18 |
