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Top Articles

#TitleJournalYearCitations
1The role and mechanisms of action of microRNAs in cancer drug resistanceClinical Epigenetics2019468
2N6-methyladenosine links RNA metabolism to cancer progressionCell Death and Disease2018381
3EGFR Tyrosine Kinase Inhibitors Activate Autophagy as a Cytoprotective Response in Human Lung Cancer CellsPLoS ONE2011217
4Roles of PFKFB3 in cancerSignal Transduction and Targeted Therapy2017189
5Long non-coding RNA NEAT1 confers oncogenic role in triple-negative breast cancer through modulating chemoresistance and cancer stemnessCell Death and Disease2019174
6Impaired autophagic degradation of lncRNA ARHGAP5-AS1 promotes chemoresistance in gastric cancerCell Death and Disease2019128
7Enolase 1 stimulates glycolysis to promote chemoresistance in gastric cancerOncotarget2017101
8Autophagy Inhibition Enhances Daunorubicin-Induced Apoptosis in K562 CellsPLoS ONE201196
9Nuclear factor of activated T cells in cancer development and treatmentCancer Letters201586
10Interaction of autophagy with microRNAs and their potential therapeutic implications in human cancersCancer Letters201581
11SOCE and cancer: Recent progress and new perspectivesInternational Journal of Cancer201677
12Exosomes from heat‐stressed tumour cells inhibit tumour growth by converting regulatory T cells to Th17 cells via IL‐6Immunology201876
13MicroRNAs in Hepatocellular Carcinoma: Regulation, Function, and Clinical ImplicationsScientific World Journal, The201373
14Inhibition of the angiogenesis and growth of Aloin in human colorectal cancer in vitro and in vivoCancer Cell International201370
15CD69 enhances immunosuppressive function of regulatory T-cells and attenuates colitis by prompting IL-10 productionCell Death and Disease201869
16CD3+CD4-CD8- (Double-Negative) T Cells in Inflammation, Immune Disorders and CancerFrontiers in Immunology202265
17SKF-96365 activates cytoprotective autophagy to delay apoptosis in colorectal cancer cells through inhibition of the calcium/CaMKIIγ/AKT-mediated pathwayCancer Letters201663
18Heat Shock Factor 1 Epigenetically Stimulates Glutaminase-1-Dependent mTOR Activation to Promote Colorectal CarcinogenesisMolecular Therapy201861
19Inflammatory microenvironment in the initiation and progression of bladder cancerOncotarget201761
20Adipocyte-derived exosomes promote lung cancer metastasis by increasing MMP9 activity via transferring MMP3 to lung cancer cellsOncotarget201760
21CircUBAP2-mediated competing endogenous RNA network modulates tumorigenesis in pancreatic adenocarcinomaAging201959
22Salvianolic acid B, a novel autophagy inducer, exerts antitumor activity as a single agent in colorectal cancer cellsOncotarget201659
23Multiple Primary Malignant Tumors - A Clinical Analysis of 15,321 Patients with Malignancies at a Single Center in ChinaJournal of Cancer201858
24Autophagy inhibition sensitizes hepatocellular carcinoma to the multikinase inhibitor linifanibScientific Reports201456
25COPS5 amplification and overexpression confers tamoxifen-resistance in ERα-positive breast cancer by degradation of NCoRNature Communications201656
26Learning efficient, explainable and discriminative representations for pulmonary nodules classificationPattern Recognition202156
27miR-26a enhances autophagy to protect against ethanol-induced acute liver injuryJournal of Molecular Medicine201552
28The role of autophagy in colitis-associated colorectal cancerSignal Transduction and Targeted Therapy201852
29Cyclosporine A sensitizes human non-small cell lung cancer cells to gefitinib through inhibition of STAT3Cancer Letters201651
30YTHDF1-enhanced iron metabolism depends on TFRC m6A methylationTheranostics202050
31Optogenetic engineering to probe the molecular choreography of STIM1-mediated cell signalingNature Communications202050
32SIRT1 deacetylated and stabilized XRCC1 to promote chemoresistance in lung cancerCell Death and Disease201944
33High‐risk Stage III colon cancer patients identified by a novel five‐gene mutational signature are characterized by upregulation of IL‐23A and gut bacterial translocation of the tumor microenvironmentInternational Journal of Cancer202043
34Prognosis of prostate cancer and bone metastasis pattern of patients: a SEER-based study and a local hospital based study from ChinaScientific Reports202043
35Analysis of potential genes and pathways associated with the colorectal normal mucosa–adenoma–carcinoma sequenceCancer Medicine201842
36Epigenetic regulation of alternative splicingAmerican Journal of Cancer Research201842
37The Efficacy and Safety of Apatinib Treatment for Patients with Unresectable or Relapsed Liver Cancer: a retrospective studyJournal of Cancer201841
38Estrogen Receptor Downregulates Expression of PD-1/PD-L1 and Infiltration of CD8+ T Cells by Inhibiting IL-17 Signaling Transduction in Breast CancerFrontiers in Oncology202041
39Linking the YTH domain to cancer: the importance of YTH family proteins in epigeneticsCell Death and Disease202140
40Prognosis and nomogram for predicting postoperative survival of duodenal adenocarcinoma: A retrospective study in China and the SEER databaseScientific Reports201838
41Growth differentiation factor–15 predicts the prognoses of patients with acute coronary syndrome: a meta-analysisBMC Cardiovascular Disorders201636
42The roles of subcellularly located EGFR in autophagyCellular Signalling201736
43Metabolic enzyme PDK3 forms a positive feedback loop with transcription factor HSF1 to drive chemoresistanceTheranostics201935
44Targeting ATF4-dependent pro-survival autophagy to synergize glutaminolysis inhibitionTheranostics202135
45Association between Dietary Vitamin A Intake and the Risk of Glioma: Evidence from a Meta-analysisNutrients201534
46Histone deacetylase 3 inhibits expression of PUMA in gastric cancer cellsJournal of Molecular Medicine201333
47Overexpressed pseudogenes, DUXAP8 and DUXAP9, promote growth of renal cell carcinoma and serve as unfavorable prognostic biomarkersAging201933
48Efficacy and safety of weekly paclitaxel with or without ramucirumab as second-line therapy for the treatment of advanced gastric or gastroesophageal junction adenocarcinoma (RAINBOW-Asia): a randomised, multicentre, double-blind, phase 3 trialThe Lancet Gastroenterology and Hepatology202132
49Tamoxifen activates Nrf2-dependent SQSTM1 transcription to promote endometrial hyperplasiaTheranostics201731
50Cell Transfer Therapy for Cancer: Past, Present, and FutureJournal of Immunology Research201430