| # | Title | Journal | Year | Citations |
|---|
| 1 | Resveratrol Reduces the Proinflammatory Effects and Lipopolysaccharide- Induced Expression of HMGB1 and TLR4 in RAW264.7 Cells | Cellular Physiology and Biochemistry | 2014 | 2,415 |
| 2 | 5-Fluorouracil: Mechanisms of Resistance and Reversal Strategies | Molecules | 2008 | 515 |
| 3 | The role of STAT3 in autophagy | Autophagy | 2015 | 354 |
| 4 | Obesity: Epidemiology, Pathophysiology, and Therapeutics | Frontiers in Endocrinology | 2021 | 339 |
| 5 | MicroRNAs as Potential Biomarkers in Cancer: Opportunities and Challenges | BioMed Research International | 2015 | 251 |
| 6 | Lactose Intolerance in Adults: Biological Mechanism and Dietary Management | Nutrients | 2015 | 245 |
| 7 | Multifidus muscle changes and clinical effects of one-level posterior lumbar interbody fusion: minimally invasive procedure versus conventional open approach | European Spine Journal | 2010 | 242 |
| 8 | Interplay between epigenetics and metabolism in oncogenesis: mechanisms and therapeutic approaches | Oncogene | 2017 | 219 |
| 9 | Oxidative stress in the pathogenesis of psoriasis | Free Radical Biology and Medicine | 2009 | 218 |
| 10 | EGFR Tyrosine Kinase Inhibitors Activate Autophagy as a Cytoprotective Response in Human Lung Cancer Cells | PLoS ONE | 2011 | 217 |
| 11 | Tau-Targeted Multifunctional Nanocomposite for Combinational Therapy of Alzheimer’s Disease | ACS Nano | 2018 | 205 |
| 12 | Ligament regeneration using a knitted silk scaffold combined with collagen matrix | Biomaterials | 2008 | 190 |
| 13 | The 14 bp deletion polymorphisms in HLA‐G gene play an important role in the expression of soluble HLA‐G in plasma | Tissue Antigens | 2008 | 178 |
| 14 | Ultrathin Molybdenum Carbide MXene with Fast Biodegradability for Highly Efficient Theory‐Oriented Photonic Tumor Hyperthermia | Advanced Functional Materials | 2019 | 150 |
| 15 | A comparison of intrauterine balloon, intrauterine contraceptive device and hyaluronic acid gel in the prevention of adhesion reformation following hysteroscopic surgery for Asherman syndrome: a cohort study | European Journal of Obstetrics, Gynecology and Reproductive Biology | 2013 | 149 |
| 16 | Astaxanthin as a Potential Neuroprotective Agent for Neurological Diseases | Marine Drugs | 2015 | 144 |
| 17 | The potential mechanism of postoperative cognitive dysfunction in older people | Experimental Gerontology | 2020 | 142 |
| 18 | Relationship between exposure to PM2.5 and lung cancer incidence and mortality: A meta-analysis | Oncotarget | 2017 | 139 |
| 19 | Dynamically Reversible Iron Oxide Nanoparticle Assemblies for Targeted Amplification of T1-Weighted Magnetic Resonance Imaging of Tumors | Nano Letters | 2019 | 137 |
| 20 | Electrospun scaffolds for multiple tissues regeneration in vivo through topography dependent induction of lineage specific differentiation | Biomaterials | 2015 | 129 |
| 21 | B7-H4(B7x)–Mediated Cross-talk between Glioma-Initiating Cells and Macrophages via the IL6/JAK/STAT3 Pathway Lead to Poor Prognosis in Glioma Patients | Clinical Cancer Research | 2016 | 128 |
| 22 | Casticin induces leukemic cell death through apoptosis and mitotic catastrophe | Annals of Hematology | 2009 | 127 |
| 23 | Fusobacterium nucleatum promotes colorectal cancer metastasis by modulating KRT7-AS/KRT7 | Gut Microbes | 2020 | 127 |
| 24 | The effect of decellularized matrices on human tendon stem/progenitor cell differentiation and tendon repair | Acta Biomaterialia | 2013 | 126 |
| 25 | Mer regulates microglial/macrophage M1/M2 polarization and alleviates neuroinflammation following traumatic brain injury | Journal of Neuroinflammation | 2021 | 126 |
| 26 | Relationship between hyperuricemia and metabolic syndrome | Journal of Zhejiang University: Science B | 2007 | 124 |
| 27 | The impact of Helicobacter pylori infection, eradication therapy and probiotic supplementation on gut microenvironment homeostasis: An open-label, randomized clinical trial | EBioMedicine | 2018 | 122 |
| 28 | Prevalence and Presentation of Lactose Intolerance and Effects on Dairy Product Intake in Healthy Subjects and Patients With Irritable Bowel Syndrome | Clinical Gastroenterology and Hepatology | 2013 | 118 |
| 29 | Remimazolam tosilate in upper gastrointestinal endoscopy: A multicenter, randomized, non‐inferiority, phase III trial | Journal of Gastroenterology and Hepatology (Australia) | 2021 | 113 |
| 30 | Binding pancreaticojejunostomy is a new technique to minimize leakage | American Journal of Surgery | 2002 | 108 |
| 31 | Quercetin attenuates doxorubicin cardiotoxicity by modulating Bmi‐1 expression | British Journal of Pharmacology | 2014 | 107 |
| 32 | Honokiol alleviates the degeneration of intervertebral disc via suppressing the activation of TXNIP-NLRP3 inflammasome signal pathway | Free Radical Biology and Medicine | 2018 | 106 |
| 33 | Deep Learning for Accurate Diagnosis of Liver Tumor Based on Magnetic Resonance Imaging and Clinical Data | Frontiers in Oncology | 2020 | 106 |
| 34 | B. adolescentis ameliorates chronic colitis by regulating Treg/Th2 response and gut microbiota remodeling | Gut Microbes | 2021 | 106 |
| 35 | Prevalence and Persistent Shedding of Fecal SARS-CoV-2 RNA in Patients With COVID-19 Infection: A Systematic Review and Meta-analysis | Clinical and Translational Gastroenterology | 2021 | 106 |
| 36 | Ferroptosis mediated DSS-induced ulcerative colitis associated with Nrf2/HO-1 signaling pathway | Immunology Letters | 2020 | 104 |
| 37 | Intra-articular delivery of sinomenium encapsulated by chitosan microspheres and photo-crosslinked GelMA hydrogel ameliorates osteoarthritis by effectively regulating autophagy | Biomaterials | 2016 | 103 |
| 38 | Bloating and Distention in Irritable Bowel Syndrome: The Role of Gas Production and Visceral Sensation After Lactose Ingestion in a Population With Lactase Deficiency | American Journal of Gastroenterology | 2013 | 102 |
| 39 | Neural Stem Cells Transfected with Reactive Oxygen Species–Responsive Polyplexes for Effective Treatment of Ischemic Stroke | Advanced Materials | 2019 | 102 |
| 40 | Renal-Clearable Hollow Bismuth Subcarbonate Nanotubes for Tumor Targeted Computed Tomography Imaging and Chemoradiotherapy | Nano Letters | 2018 | 101 |
| 41 | Randomized, controlled trial comparing the efficacy of intrauterine balloon and intrauterine contraceptive device in the prevention of adhesion reformation after hysteroscopic adhesiolysis | Fertility and Sterility | 2015 | 99 |
| 42 | Traditional Chinese medicine for pulmonary fibrosis therapy: Progress and future prospects | Journal of Ethnopharmacology | 2017 | 98 |
| 43 | Percutaneous vertebroplasty versus balloon kyphoplasty for treatment of osteoporotic vertebral compression fracture: a meta-analysis of randomised and non-randomised controlled trials | International Orthopaedics | 2011 | 96 |
| 44 | Akkermansia muciniphila Alleviates Dextran Sulfate Sodium (DSS)-Induced Acute Colitis by NLRP3 Activation | Microbiology Spectrum | 2021 | 96 |
| 45 | An Assessment of the Intra- and Inter-reliability of the Lumbar Paraspinal Muscle Parameters Using CT Scan and Magnetic Resonance Imaging | Spine | 2011 | 93 |
| 46 | High-resolution computed tomography manifestations of COVID-19 infections in patients of different ages | European Journal of Radiology | 2020 | 92 |
| 47 | Soluble uric acid increases PDZK1 and ABCG2 expression in human intestinal cell lines via the TLR4-NLRP3 inflammasome and PI3K/Akt signaling pathway | Arthritis Research and Therapy | 2018 | 91 |
| 48 | Orientation in multi-layer chitosan hydrogel: morphology, mechanism and design principle | Scientific Reports | 2015 | 90 |
| 49 | Fusobacterium nucleatum promotes colorectal cancer metastasis through miR-1322/CCL20 axis and M2 polarization | Gut Microbes | 2021 | 90 |
| 50 | The Polarization States of Microglia in TBI: A New Paradigm for Pharmacological Intervention | Neural Plasticity | 2017 | 88 |
